Related books on 'X-ray-Crystallography'

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by: Jan Drenth
publisher: Springer, published: 2006-11-09
ASIN: 0387333347
EAN: 9780387333342
sales rank: 451712

X-ray crystallography is an established method for studying the structure of proteins and other macromolecules. As the importance of proteins grows, researchers in many fields have found that a working knowledge of X-ray diffraction is an indispensable tool. In this new edition of his essential work, the internationally recognized researcher Dr. Jan Drenth offers an up-to-date and technically rigorous introduction to the subject, providing the theoretical background necessary to understand how the structure of proteins is determined at atomic resolution. New material in the 3rd edition includes a section on twinning, an additional chapter on crystal growth and a discussion of single-wavelength anomalous dispersion.


by: Christopher Hammond
publisher: Oxford University Press, USA, published: 2009-06-15
ASIN: 0199546452
EAN: 9780199546459
sales rank: 527430
This book provides a clear introduction to topics which are essential to students in a wide range of scientific disciplines but which are otherwise only covered in specialised and mathematically detailed texts. It shows how crystal structures may be built up from simple ideas of atomic packing and co-ordination, it develops the concepts of crystal symmetry, point and space groups by way of two dimensional examples of patterns and tilings, it explains the concept of the reciprocal lattice in simple terms and shows its importance in an understanding of light, X-ray and electron diffraction. Practical examples of the applications of these techniques are described and also the importance of diffraction in the performance of optical instruments.

The book is also of value to the general reader since it shows, by biographical and historical references, how the subject has developed and thereby indicates some of the excitement of scientific discovery.

by: Gale Rhodes
publisher: Academic Press, published: 2006-03-02
ASIN: 0125870736
EAN: 9780125870733
sales rank: 240503
Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs.

* Helps readers to understand where models come from, so they don't use them blindly and
inappropriately
* Provides many visual and geometric models for understanding a largely mathematical method
* Allows readers to judge whether recently published models are of sufficiently high quality and detail to be useful in their own work
* Allows readers to study macromolecular structure independently and in an open-ended fashion on their own computers, without being limited to textbook or journals illustrations
* Provides access to web tools in a format that will not go out of date. Links will be updated and added as existing resources change location or are added

by: Christopher Hammond
publisher: Oxford University Press, USA, published: 2001-06-21
ASIN: 0198505523
EAN: 9780198505525
sales rank: 597589
This is a clear and comprehensive introduction to the topics of crystallography and diffraction for undergraduate and beginning graduate students and lecturers in physics, chemistry, materials, and earth sciences. It shows how crystal structures may be built up from simple ideas of atomic packing and co-ordination, and develops the concepts of crystal symmetry, point and space groups by way of two-dimensional examples of patterns and tilings. The concept of the reciprocal lattice is explained in simple terms and its importance in an understanding o light, x-ray and electron diffraction. Finally, the book covers practical examples of the applications of these techniques and describes the importance of diffraction in the performance of optical instruments.

by: Emilio Segre
publisher: Dover Publications, published: 2007-06-05
ASIN: 0486457834
EAN: 9780486457833
sales rank: 547453
A Nobel Laureate offers impressions and recollections of the development of modern physics. Rather than a chronological approach, Segrè emphasizes interesting, complex personalities who often appear only in footnotes. Readers will find that this book adds considerably to their understanding of science and includes compelling topics of current interest. 1980 edition.

by: Dennis Sherwood
publisher: Oxford University Press, USA, published: 2010-12-30
ASIN: 019955904X
EAN: 9780199559046
sales rank: 453226
A complete account of the theory of the diffraction of x-rays by crystals with particular reference to the processes of determining the structures of protein molecules, this book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus.

The book covers a host of important topics in the area, including:
- The practical aspects of sample preparation and x-ray data collection, using both laboratory and synchrotron sources
- Data analysis at both theoretical and practical levels
- The important role played by the Patterson function in structure analysis by both molecular replacement and experimental phasing approaches
- Methods for improving the resulting electron density map
- The theoretical basis of methods used in refinement of protein crystal structures
- In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules
- The complementary roles of other diffraction methods which reveal further detail of great functional importance in a crystal structure.

by: William Clegg
publisher: Oxford University Press, USA, published: 1998-07-16
ASIN: 0198559011
EAN: 9780198559016
sales rank: 330009
This informative book explains the principles and practice of one of the most important methods of determining the structures of molecules, a subject of central interest in modern chemistry. It includes a set of case studies to illustrate how the method works. Mathematical treatment is kept at a relatively low level and is complemented by extensive graphical illustrations.

by: George H. Stout
publisher: Wiley-Interscience, published: 1989-04-24
ASIN: 0471607118
EAN: 9780471607113
sales rank: 901629
Closely follows an actual structural determination. After some introductory material on the nature of x-rays, the diffraction process, and the internal geometry of crystals, the selection and preparation of a crystal are considered. Techniques of measuring raw x-ray data are covered, plus their reduction into a useable form. The second part discusses both traditional and novel methods of solving the ``phase'' problem, the principal difficulty in x-ray structure determination. The third part considers how to extract the most information from the data and how to evaluate its reliability. Finally, there is a discussion of sources of error in practice and interpretation.

by: Li-ling Ooi
publisher: Oxford University Press, USA, published: 2010-05-02
ASIN: 0199569045
EAN: 9780199569045
sales rank: 1082761
X-ray crystallography has long been a powerful tool in the elucidation of the three-dimensional structures of small molecules and macromolecules. However, despite its power, it is a technically challenging subject that those new to the technique often find daunting.

An ideal primer for students encountering the technique for the first time, Principles of X-ray Crystallography provides a clear, succinct guide to the three-dimensional world of molecules. Featuring a lucid and direct writing style, real-life examples, diagrams, exercises, and activities, this unique text engages students in visualizing three-dimensional structures, rather than overwhelming them with excessive detail.

Author Li-ling Ooi explores both the theoretical principles on which the technique is based and the practice of gathering and analyzing crystallographic data, offering a balanced, well-rounded account of the field. Drawing on valuable teaching experience, Ooi employs a tutorial approach--including self-test exercises and hands-on activities--that leads students through key concepts in a carefully structured and evenly paced manner.

The text encompasses aspects of both small molecule and macromolecular crystallography, highlighting the similarities and differences between the two. A companion website features resources for students--a library of annotated web links and data sets related to topics discussed in the book--and instructors--downloadable figures from the book in electronic format and PowerPoint slide sets for each chapter.

by: Werner Massa
publisher: Springer, published: 2011-11-30
ASIN: 3540206442
EAN: 9783540206446
sales rank: 394026
This textbook gives a concise introduction to modern crystal structure determination, emphasising both its theoretical background and the way it is actually carried out. The theoretical sections are supported by many illustrations, and lay emphasis on a good understanding rather than rigorous mathematics. The most important data collection techniques, and the methods of data reduction, structure solution and refinement are discussed from a practical point of view. Many tips and insights help readers to recognise and avoid possible errors and traps, and to judge the quality of results. The second edition has been considerably updated, especially the chapter on experimental methods, which is now mainly concerned with modern data collection using area-detectors.
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