Life science and biomedical books

Related books on 'animal-model'

	Biodefense Research Methodology and Animal Models, Second Edition publisher: CRC Press, published: 2012-02-07 ASIN: 1439836329 EAN: 9781439836323 sales rank: 395333 Significant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA’s Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Research Methodology and Animal Models, Second Edition spans the spectrum of coverage from basic research to advanced development of medical countermeasures. Topics discussed in this volume include: A history of biological agents as weapons, from the use of corpses to contaminate water supplies to modern day anthrax attacks Concepts and strategies involved in biowarfare and bioterrorism The development, validation, and importance of animal models in biodefense research Infectious disease aerobiology Studies involving anthrax, glanders, plague, tularemia, Q fever, alphaviruses, orthopoxviruses, and a new chapter on brucellosis Animal models for viral hemorrhagic fevers Botulinum and Ricin toxins Staphylococcal and streptococcal superantigens As the scientific community works diligently to protect the world’s population from the misuse of infectious organisms and toxins, it is imperative that researchers stay abreast of the latest techniques for biodefense research. Exploring in vivo and in vitro assays, this volume brings researchers up to date on the latest information on bacterial and viral infectious agents and biological toxins considered to pose the greatest threats to public safety. In addition, the contributors take a step toward minimizing the use of animals in further experiments by presenting documented findings that can be built upon.
	Early Intervention Games: Fun, Joyful Ways to Develop Social and Motor Skills in Children with Autism Spectrum or Sensory Processing Disorders by: Barbara Sher publisher: Jossey-Bass, published: 2009-10-26 ASIN: 047039126X EAN: 9780470391266 sales rank: 5756 A resource of fun games for parents or teachers to help young children learn social and motor skills Barbara Sher, an expert occupational therapist and teacher, has written a handy resource filled with games to play with young children who have Autistic Spectrum Disorder (ASD) or other sensory processing disorders (SPD). The games are designed to help children feel comfortable in social situations and teach other basic lessons including beginning and end, spatial relationships, hand-eye coordination, and more. Games can also be used in regular classrooms to encourage inclusion. A collection of fun, simple games that can improve the lives of children with ASD or other SPDs. Games can be played by parents or teachers and with individual children or groups. Games are designed to make children more comfortable in social situations and to develop motor and language skills Also included are a variety of interactive games to play in water, whether in a backyard kiddie pool, community swimming pool, or lake All the games are easy-to-do, utilizing common, inexpensive materials, and include several variations and modifications
	Modeling Infectious Diseases in Humans and Animals by: Matt J. Keeling publisher: Princeton University Press, published: 2007-10-08 ASIN: 0691116172 EAN: 9780691116174 sales rank: 263765 For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. Comprehensive, practical introduction to infectious disease modeling Builds from simple to complex predictive models Models and methodology fully supported by examples drawn from research literature Practical models aid students' understanding of fundamental epidemiological processes For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB In-depth treatment of role of modeling in understanding disease control
	Of Mice, Models, and Men: A Critical Evaluation of Animal Research by: Andrew N. Rowan publisher: State University of New York Press, published: 1984-06-30 ASIN: 0873957776 EAN: 9780873957779 sales rank: 799727
	Animal Origami for the Enthusiast: Step-by-Step Instructions in Over 900 Diagrams/25 Original Models (Dover Origami Papercraft) by: John Montroll publisher: Dover Publications, published: 1985-03-01 ASIN: 0486247929 EAN: 9780486247922 sales rank: 125890 Challenging new collection of paper sculptures designed by renowned origami expert presents 25 intricately detailed paperfolding projects featuring strikingly life-like animals — angelfish, walrus, eagle, turtle, frog, antelope, lobster, tyrannosaurus, more. Fully illustrated step-by-step instructions and hundreds of diagrams guide origamists. Introduction. Instructions. Over 900 diagrams.
	Sourcebook of Models for Biomedical Research publisher: Humana Press, published: 2007-12-11 ASIN: 1588299333 EAN: 9781588299338 sales rank: 1187906 The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.
	Germfree and Gnotobiotic Animal Models Background and Applications by: Bernard S. Wostmann publisher: CRC-Press, published: 1996-08-19 ASIN: 084934008X EAN: 9780849340086 sales rank: 559901 The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. The need for such an animal model for use in biomedical studies was first expressed by Pasteur in the late 1800s. Subsequent development of germfree and gnotobiotic animals led to an explosion of studies on the effects of microflora and its components on the physiology and metabolism of the host. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.
	Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments, Volume 2 (Springer Protocols Handbooks) publisher: Humana Press, published: 2012-04-30 ASIN: 1617797812 EAN: 9781617797811 The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries.  Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system.  Volume 2 examines global cerebral ischemia, focal cerebral ischemia, and neonatal hypoxia-ischemia, as well as intensive sections covering traumatic brain injury and spinal cord injury.  Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used.   Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.
	In vivo Imaging of Animal Models: Stroke publisher: Springer, published: 2012-03-28 ASIN: 9400715471 EAN: 9789400715479 sales rank: 11174304 Animal models play an important role for the understanding of disease mechanisms and treatment approaches but also for the validation of new methods in disease diagnosis. Molecular and other non-invasive imaging tools provide the means for monitoring the temporally resolved development of the disease and correlate major aspects like pathophysiology, behaviour, structural, metabolic and functional findings. This book provides a comprehensive summary of major molecular imaging modalities and their application to stroke animal models. Basic aspects of working with animal models and the translation into clinical research are provided. The book comprises aspects of various stroke animal models, disease progression and treatment approaches (from conventional approaches to the assessment of cell-based therapy) and on the other hand an introduction in modern imaging methodology such as MRI, PET and optical imaging. It is the aim of this book to provide an introduction into pathophysiological aspects of stroke animal models to scientists and into molecular imaging methods to clinicians and scientists in basic and clinical research. The chapters link imaging, pathology and clinical research.
	Experimental Surgical Models in the Laboratory Rat publisher: CRC Press, published: 2009-05-19 ASIN: 1420093266 EAN: 9781420093261 sales rank: 1769763 An All-Inclusive Guide to Surgical Techniques on Rats The design of an adequate surgical model, like the choice of the animal model itself, is extremely important for obtaining reliable valuable data. Experimental Surgical Models in the Laboratory Rat summarizes a series of techniques that were applied in the Bone Biology Laboratories, School of Medicine, Rosario National University, Argentina. Stopping just short of an exhaustive analysis of the techniques, this manual describes the basics of each surgical technique, the necessary materials, precautions to consider, the methodology to apply, and the possible results to be obtained in similar experiments. CD-ROM: 250 Illustrations of Surgery Techniques with Step-by-Step Instruction With succinct descriptions, color photographs, and easy-to-follow steps, the attached CD-ROM is a practical, full-color roadmap for performing various surgery techniques, such as catheterization, tracheostomy, intramuscular injection, subcutaneous injection, intraperitoneal injection, and oral intubation. This definitive work provides technical and practical data including volumes and concentrations of solutions, catheters used, equipment, and biological variables on the rat. Experimental Surgical Models in the Laboratory Rat is a complete reference for today’s biomedical sciences investigator.

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