Related books on 'bioinformatics'

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by: Jean-Michel Claverie Ph. D.
publisher: For Dummies, published: 2006-12-18
ASIN: 0470089857
EAN: 9780470089859
sales rank: 120578
Were you always curious about biology but were afraid to sit through long hours of dense reading? Did you like the subject when you were in high school but had other plans after you graduated? Now you can explore the human genome and analyze DNA without ever leaving your desktop!

Bioinformatics For Dummies is packed with valuable information that introduces you to this exciting new discipline. This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You’ll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to:

  • Analyze all types of sequences
  • Use all types of databases
  • Work with DNA and protein sequences
  • Conduct similarity searches
  • Build a multiple sequence alignment
  • Edit and publish alignments
  • Visualize protein 3-D structures
  • Construct phylogenetic trees

This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what’s going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you’ll be searching databases and analyzing sequences like a pro!


by: Jonathan Pevsner
publisher: Wiley-Blackwell, published: 2009-05-04
ASIN: 0470085851
EAN: 9780470085851
sales rank: 70965
The bestselling introduction to bioinformatics and functional genomics—now in an updated edition

Widely received in its previous edition, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded Second Edition, it continues to be the go-to source for students and professionals involved in biomedical research.

This edition provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include:

  • Several fundamentally important proteins, such as globins, histones, insulin, and albumins, are included to better show how to apply bioinformatics tools to basic biological questions.
  • A completely updated companion web site, which will be updated as new information becomes available - visit www.wiley.com/go/pevsnerbioinformatics
  • Descriptions of genome sequencing projects spanning the tree of life.
  • A stronger focus on how bioinformatics tools are used to understand human disease.

The book is complemented by lavish illustrations and more than 500 figures and tables—fifty of which are entirely new to this edition. Each chapter includes a Problem Set, Pitfalls, Boxes explaining key techniques and mathematics/statistics principles, Summary, Recommended Reading, and a list of freely available software. Readers may visit a related Web page for supplemental information at www.wiley.com/go/pevsnerbioinformatics.

Bioinformatics and Functional Genomics, Second Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.

Praise for the first edition:

"...ideal both for biologists who want to master the application of bioinformatics to real-world problems and for computer scientists who need to understand the biological questions that motivate algorithms." Quarterly Review of Biology

"… an excellent textbook for graduate students and upper level undergraduate students." Annals of Biomedical Engineering

"…highly recommended for academic and medical libraries, and for researchers as an introduction and reference…" E-Streams


by: James Tisdall
publisher: O'Reilly Media, published: 2001-10-15
ASIN: 0596000804
EAN: 9780596000806
sales rank: 75185

With its highly developed capacity to detect patterns in data, Perl has become one of the most popular languages for biological data analysis. But if you're a biologist with little or no programming experience, starting out in Perl can be a challenge. Many biologists have a difficult time learning how to apply the language to bioinformatics. The most popular Perl programming books are often too theoretical and too focused on computer science for a non-programming biologist who needs to solve very specific problems.

Beginning Perl for Bioinformatics is designed to get you quickly over the Perl language barrier by approaching programming as an important new laboratory skill, revealing Perl programs and techniques that are immediately useful in the lab. Each chapter focuses on solving a particular bioinformatics problem or class of problems, starting with the simplest and increasing in complexity as the book progresses. Each chapter includes programming exercises and teaches bioinformatics by showing and modifying programs that deal with various kinds of practical biological problems. By the end of the book you'll have a solid understanding of Perl basics, a collection of programs for such tasks as parsing BLAST and GenBank, and the skills to take on more advanced bioinformatics programming. Some of the later chapters focus in greater detail on specific bioinformatics topics. This book is suitable for use as a classroom textbook, for self-study, and as a reference.

The book covers:

  • Programming basics and working with DNA sequences and strings
  • Debugging your code
  • Simulating gene mutations using random number generators
  • Regular expressions and finding motifs in data
  • Arrays, hashes, and relational databases
  • Regular expressions and restriction maps
  • Using Perl to parse PDB records, annotations in GenBank, and BLAST output

by: Mitchell L. Model
publisher: O'Reilly Media, published: 2009-12-22
ASIN: 059615450X
EAN: 9780596154509
sales rank: 245282

Powerful, flexible, and easy to use, Python is an ideal language for building software tools and applications for life science research and development. This unique book shows you how to program with Python, using code examples taken directly from bioinformatics. In a short time, you'll be using sophisticated techniques and Python modules that are particularly effective for bioinformatics programming.

Bioinformatics Programming Using Python is perfect for anyone involved with bioinformatics -- researchers, support staff, students, and software developers interested in writing bioinformatics applications. You'll find it useful whether you already use Python, write code in another language, or have no programming experience at all. It's an excellent self-instruction tool, as well as a handy reference when facing the challenges of real-life programming tasks.

  • Become familiar with Python's fundamentals, including ways to develop simple applications
  • Learn how to use Python modules for pattern matching, structured text processing, online data retrieval, and database access
  • Discover generalized patterns that cover a large proportion of how Python code is used in bioinformatics
  • Learn how to apply the principles and techniques of object-oriented programming
  • Benefit from the "tips and traps" section in each chapter

by: Conrad Bessant
publisher: Oxford University Press, USA, published: 2009-02-28
ASIN: 0199230234
EAN: 9780199230235
sales rank: 183936
Modern bioinformatics encompasses a broad and ever-changing range of activities involved with the management and analysis of data from molecular biology experiments. Despite the diversity of activities and applications, the basic methodology and core tools needed to tackle bioinformatics problems is common to many projects. Building Bioinformatics Solutions provides a comprehensive introduction to this methodology, explaining how to acquire and use the most popular development tools, how to apply them to build processing pipelines, and how to make the results available through visualizations and web-based services for deployment either locally or via the Internet. The main development tools covered in this book are the MySQL database management system, the Perl programming language, and the R language for statistical computing. These industry standard open source tools form the core of many bioinformatics projects, both in academia and industry. The methodologies introduced are platform independent, and all the examples that feature have been tested on Windows, Linux and Mac OS.

This advanced textbook is suitable for graduate students and researchers in the life sciences who wish to automate analyses or create their own databases and web-based tools. No prior knowledge of software development is assumed. Having worked through the book, the reader should have the necessary core skills to develop computational solutions for their specific research programmes. The book will also help the reader overcome the inertia associated with penetrating this field, and provide them with the confidence and understanding required to go on to develop more advanced bioinformatics skills.

by: Neil C. Jones
publisher: The MIT Press, published: 2004-08-06
ASIN: 0262101068
EAN: 9780262101066
sales rank: 116819

This introductory text offers a clear exposition of the algorithmic principles driving advances in bioinformatics. Accessible to students in both biology and computer science, it strikes a unique balance between rigorous mathematics and practical techniques, emphasizing the ideas underlying algorithms rather than offering a collection of apparently unrelated problems.The book introduces biological and algorithmic ideas together, linking issues in computer science to biology and thus capturing the interest of students in both subjects. It demonstrates that relatively few design techniques can be used to solve a large number of practical problems in biology, and presents this material intuitively.An Introduction to Bioinformatics Algorithms is one of the first books on bioinformatics that can be used by students at an undergraduate level. It includes a dual table of contents, organized by algorithmic idea and biological idea; discussions of biologically relevant problems, including a detailed problem formulation and one or more solutions for each; and brief biographical sketches of leading figures in the field. These interesting vignettes offer students a glimpse of the inspirations and motivations for real work in bioinformatics, making the concepts presented in the text more concrete and the techniques more approachable.PowerPoint presentations, practical bioinformatics problems, sample code, diagrams, demonstrations, and other materials can be found at the Author's website.


by: James D. Tisdall
publisher: O'Reilly Media, published: 2003-06
ASIN: 0596003072
EAN: 9780596003074
sales rank: 332466

Historically, programming hasn't been considered a critical skill for biologists. But now, with access to vast amounts of biological data contained in public databases, programming skills are increasingly in strong demand in biology research and development. Perl, with its highly developed capacities in string handling, text processing, networking, and rapid prototyping, has emerged as the programming language of choice for biological data analysis.

Mastering Perl for Bioinformatics covers the core Perl language and many of its module extensions, presenting them in the context of biological data and problems of pressing interest to the biological community. This book, along with Beginning Perl for Bioinformatics, forms a basic course in Perl programming. This second volume finishes the basic Perl tutorial material (references, complex data structures, object-oriented programming, use of modules--all presented in a biological context) and presents some advanced topics of considerable interest in bioinformatics.

The range of topics covered in Mastering Perl for Bioinformatics prepares the reader for enduring and emerging developments in critical areas of bioinformatics programming such as:

  • Gene finding
  • String alignment
  • Methods of data storage and retrieval (SML and databases)
  • Modeling of networks (graphs and Petri nets)
  • Graphics (Tk)
  • Parallelization
  • Interfacing with other programming languages
  • Statistics (PDL)
  • Protein structure determination
  • Biological models of computation (DNA Computers)
Biologists and computer scientists who have conquered the basics of Perl and are ready to move even further in their mastery of this versatile language will appreciate the author's well-balanced approach to applying Perl's analytical abilities to the field of bioinformatics. Full of practical examples and real-world biological problem solving, this book is a must for any reader wanting to move beyond beginner level Perl in bioinformatics.

by: Arthur Lesk
publisher: Oxford University Press, USA, published: 2008-06-02
ASIN: 0199208042
EAN: 9780199208043
sales rank: 156956
An Introduction to Bioinformatics introduces students to the immense power of bioinformatics as a set of scientific tools. The book explains how to access the data archives of genomes and proteins, and the kinds of questions these data and tools can answer, such as how to make inferences from data archives and how to make connections among them to derive useful and interesting predictions.

Blending factual content with many opportunities for active learning, An Introduction to Bioinformatics offers a truly reader-friendly way to get to grips with this subject, making it the ideal resource for anyone new to the field.

Features
- Strikes a careful balance between biology and computer science, introducing those aspects of computer science which underpin the subject without demanding detailed prior knowledge.
- Contains numerous learning features, including exercises, problems, and WebLems.
- Retains the eloquent style and clarity of explanation for which the author is renowned.
- An Online Resource Centre includes figures from the book available to download to facilitate lecture preparation, as well as a variety of interactive resources, including web links, 3D structures, and data sets.
ew to this Edition
- New chapter on biological organization in space and reflects recent advances in genomics, transcriptomics, proteomics, and metabolomics.
- New chapter on scientific publications and archives provides a state of the art inventory on sourcing scientific literature.
- Expanded coverage of structural bioinformatics.
- Enhanced Online Resource Centre, with new guided tours of key websites, and lab assignments to support the in-depth exploration of concepts and themes covered in the book.

by: Wing-Kin Sung
publisher: Chapman and Hall/CRC, published: 2009-11-24
ASIN: 1420070339
EAN: 9781420070330
sales rank: 431000

Thoroughly Describes Biological Applications, Computational Problems, and Various Algorithmic Solutions

Developed from the author’s own teaching material, Algorithms in Bioinformatics: A Practical Introduction provides an in-depth introduction to the algorithmic techniques applied in bioinformatics. For each topic, the author clearly details the biological motivation and precisely defines the corresponding computational problems. He also includes detailed examples to illustrate each algorithm and end-of-chapter exercises for students to familiarize themselves with the topics. Supplementary material is available at http://www.comp.nus.edu.sg/~ksung/algo_in_bioinfo/

This classroom-tested textbook begins with basic molecular biology concepts. It then describes ways to measure sequence similarity, presents simple applications of the suffix tree, and discusses the problem of searching sequence databases. After introducing methods for aligning multiple biological sequences and genomes, the text explores applications of the phylogenetic tree, methods for comparing phylogenetic trees, the problem of genome rearrangement, and the problem of motif finding. It also covers methods for predicting the secondary structure of RNA and for reconstructing the peptide sequence using mass spectrometry. The final chapter examines the computational problem related to population genetics.


publisher: Wiley-Blackwell, published: 2009-03-16
ASIN: 0470181052
EAN: 9780470181058
sales rank: 111946
Structural Bioinformatics was the first major effort to show the application of the principles and basic knowledge of the larger field of bioinformatics to questions focusing on macromolecular structure, such as the prediction of protein structure and how proteins carry out cellular functions, and how the application of bioinformatics to these life science issues can improve healthcare by accelerating drug discovery and development. Designed primarily as a reference, the first edition nevertheless saw widespread use as a textbook in graduate and undergraduate university courses dealing with the theories and associated algorithms, resources, and tools used in the analysis, prediction, and theoretical underpinnings of DNA, RNA, and proteins.

This new edition contains not only thorough updates of the advances in structural bioinformatics since publication of the first edition, but also features eleven new chapters dealing with frontier areas of high scientific impact, including: sampling and search techniques; use of mass spectrometry; genome functional annotation; and much more.

Offering detailed coverage for practitioners while remaining accessible to the novice, Structural Bioinformatics, Second Edition is a valuable resource and an excellent textbook for a range of readers in the bioinformatics and advanced biology fields.

Praise for the previous edition:

"This book is a gold mine of fundamental and practical information in an area not previously well represented in book form."
—Biochemistry and Molecular Education

"... destined to become a classic reference work for workers at all levels in structural bioinformatics...recommended with great enthusiasm for educators, researchers, and graduate students."
—BAMBED

"...a useful and timely summary of a rapidly expanding field."
—Nature Structural Biology

"...a terrific job in this timely creation of a compilation of articles that appropriately addresses this issue."
—Briefings in Bioinformatics

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