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by: Lloyd R. Snyder
publisher: Wiley, published: 2009-12-09
ASIN: 0470167548
EAN: 9780470167540
sales rank: 385230
The latest edition of the authoritative reference to HPLCHigh-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: - The basis of HPLC separation and the general effects of different experimental conditions
- Equipment and detection
- The column—the "heart" of the HPLC system
- Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques
- Computer simulation, qualitative and quantitative analysis, and method validation and quality control
- The separation of large molecules, including both biological and synthetic polymers
- Chiral separations, preparative separations, and sample preparation
- Systematic development of HPLC separations—new to this edition
- Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms
Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.
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by: Veronika R. Meyer
publisher: Wiley, published: 2010-05-25
ASIN: 0470682175
EAN: 9780470682173
sales rank: 225397
Jump into the HPLC adventure!Three decades on from publication of the 1st German edition of Veronika Meyer's book on HPLC, this classic text remains one of the few titles available on general HPLC aimed at practitioners. New sections on the following topics have been included in this fifth edition: - Comparison of HPLC with capillary electrophoresis
- How to obtain peak capacity
- van Deemter curves and other coherences
- Hydrophilic interaction chromatography
- Method transfer
- Comprehensive two-dimensional HPLC
- Fast separations at 1000 bar
- HPLC with superheated water
In addition, two chapters on the instrument test and troubleshooting in the appendix have been updated and expanded by Bruno E. Lendi, and many details have been improved and numerous references added. A completely new chapter is presented on quality assurance covering: - Is it worth the effort?
- Verification with a second method
- Method validation
- Standard operating procedures
- Measurement uncertainty
- Qualifications, instrument test, and system suitability test
- The quest for quality
Reviews of earlier editions "That this text is written by an expert in both the practice and teaching of HPLC is evident from the first paragraph....not only an enjoyable, fascinating and easy read, but a truly excellent text that has and will serve many teachers, students and practitioners very well." —The Analyst “…provides essential information on HPLC for LC practitioners in academia, industry, government, and research laboratories…a valuable introduction." - American Journal of Therapeutics
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by: Raymond P.W. Scott
publisher: Reese-Scott Partnership, published: 2012-01-23
ASIN: B0071BI332
sales rank: 375696
Chromatography is probably the most powerful and versatile technique available to the chemical analyst. In this concise but comprehensive introduction, by a renowned author, both the physico-chemical principles and their practical application are explained and illustrated with many useful examples. This book will be of great value not only to the beginner, but also to the more experienced analytical practitioner, enabling a deep understanding of the molecular science behind chromatography and facilitating the wise choise of operating conditions to effect a particular separation. The book's wide coverage, clear illustrations and easily readable text will make it an accessible and indispensable asset to the laboratory scientist and technician.
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by: Harold M. McNair
publisher: Wiley-Interscience, published: 2009-07-07
ASIN: 0470439548
EAN: 9780470439548
sales rank: 386580
The New Edition of the Well-Regarded Handbook on Gas ChromatographySince the publication of the highly successful first edition of Basic Gas Chromatography, the practice of chromatography has undergone several notable developments. Basic Gas Chromatography, Second Edition covers the latest in the field, giving readers the most up-to-date guide available, while maintaining the first edition's practical, applied approach to the subject and its accessibility to a wide range of readers. The text provides comprehensive coverage of basic topics in the field, such as stationary phases, packed columns and inlets, capillary columns and inlets, detectors, and qualitative and quantitative analysis. At the same time, the coverage also features key additions and updated topics including: Gas chromatography-mass spectrometry (GC-MS) Sampling methods Multidimensional gas chromatography Fast gas chromatography Gas chromatography analysis of nonvolatile compounds Inverse gas chromatography and pyrolysis gas chromatography
Along with these new and updated topics, the references, resources, and Web sites in Basic Gas Chromatography have been revised to reflect the state of the field. Concise and fundamental in its coverage, Basic Gas Chromatography, Second Edition remains the standard handbook for everyone from undergraduates studying analytical chemistry to working industrial chemists.
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by: James S. Fritz
publisher: Wiley-VCH, published: 2009-04-14
ASIN: 3527320520
EAN: 9783527320523
sales rank: 672198
This completely revised and updated fourth edition of the best-selling classic is a thorough treatment of the subject while remaining concise and readable. New additions include capillary electrophoresis, monolithic columns, zwitterion colums, DNA/RNA analysis, fundamentals of the science of IC, and micro methods. The whole is rounded off by handy tables with details on detection or elution conditions, among others.
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by: James M. Miller
publisher: Wiley-Interscience, published: 2009-08-17
ASIN: 0470530251
EAN: 9780470530252
sales rank: 951348
The first edition of Chromatography: Concepts and Contrasts, published in 1988, was one of the first books to discuss all the different types of chromatography under one cover. The second edition continues with these principles but has been updated to include new chapters on sampling and sample preparation, capillary electrophoresis and capillary electrochromatography (CEC), chromatography with mass spec detection, and industrial and governmental practices in regulated industries.- Covers extraction, solid phase extraction (SPE), and solid phase microextraction (SPME), and introduces mass spectrometry
- Updated with the latest techniques in chromatography
- Discusses both liquid chromatography (LC)and gas chromatography(GC)
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by: O David Sparkman
publisher: Academic Press, published: 2011-04-13
ASIN: 0123736285
EAN: 9780123736284
sales rank: 293736
The second edition of Gas Chromatography and Mass Spectrometry: A Practical Guide follows the highly successful first edition by F.G. Kitson, B.S. Larsen, and C.N. McEwen (1996), which was designed as an indispensible resource for GC/MS practitioners regardless of whether they are a novice or well experienced. The Fundamentals section has been extensively reworked from the original edition to give more depth of an understanding of the techniques and science involved with GC/MS. Even with this expansion, the original brevity and simple didactic style has been retained. Information on chromatographic peak deconvolution has been added along with a more in-depth understanding of the use of mass spectral databases in the identification of unknowns. Since the last edition, a number of advances in GC inlet systems and sample introduction techniques have occurred, and they are included in the new edition. Other updates include a discussion on fast GC and options for combining GC detectors with mass spectrometry. The section regarding GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types has the same number of compound types as the original edition, but the information in each section has been expanded to not only explain some of the spectra but to also explain why certain fragmentations take place. The number of Appendices has been increased from 12 to 17. The Appendix on Atomic Masses and Isotope Abundances has been expanded to provide tools to aid in determination of elemental composition from isotope peak intensity ratios. An appendix with examples on "Steps to follow in the determination of elemental compositions based on isotope peak intensities" has been added. Appendices on whether to use GC/MS or LC/MS, third-party software for use in data analysis, list of information required in reporting GC/MS data, X+1 and X+2 peak relative intensities based on the number of atoms of carbon in an ion, and list of available EI mass spectral databases have been added. Others such as the ones on derivatization, isotope peak patterns for ions with Cl and/or Br, terms used in GC and in mass spectrometry, and tips on setting up, maintaining and troubleshooting a GC/MS system have all been expanded and updated.
- Covers the practical instruction necessary for successful operation of GC/MS equipment
- Reviews the latest advances in instrumentation, ionization methods, and quantitation
- Includes troubleshooting techniques and a variety of additional information useful for the GC/MS practitioner
- A true benchtop reference
- A guide to a basic understanding of the components of a Gas Chromatograph-Mass Spectrometer (GC-MS)
- Quick References to data interpretation
- Ready source for information on new analyses
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publisher: CRC Press, published: 2006-10-25
ASIN: 1574447351
EAN: 9781574447354
sales rank: 2918085
For more than four decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. Volume 45 of this authoritative series once again compiles the work of expert contributors in order to present timely and cutting-edge reviews on a variety of related topics.
This volume focuses on applying various chromatographic techniques to combinatorial methods and high-throughput analyses. The authors address various limitations to traditional techniques and present developments that enable scientists to analyze a higher volume of smaller molecules under high-throughput conditions more efficiently. Other practical topics include discussions of selection criteria for using alternative solvents and reagents, minimum requirements for utilizing readily available instrumentation and methods for new applications, the use of high-throughput purification for obtaining higher quality leads, and new chromatographic data on organic endocrine disrupters.
Advances in Chromatography: Volume 45 provides a good starting point to gain quick and up-to-date knowledge of the field and its most recent developments. Each author's clear presentation of topics and vivid illustrations make the material accessible and engaging to a variety of chemists with different levels of technical skill.
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by: Wilfried M.A. Niessen
publisher: CRC Press, published: 2006-08-09
ASIN: 0824740823
EAN: 9780824740825
sales rank: 1640607
A constructive evaluation of the most significant developments in liquid chromatography–mass spectrometry (LC–MS) and its uses for quantitative bioanalysis and characterization for a diverse range of disciplines, Liquid Chromatography–Mass Spectrometry, Third Edition offers a well-rounded coverage of the latest technological developments and applications. As the technology itself has matured into a reliable analytical method over the last 15 years, the most exciting developments occur in LC–MS augments research into new applications. This edition places a stronger emphasis than previous editions on the impact of LC–MS methods, dedicating two-thirds of the text to small-molecule and biomolecular applications such as proteomics, pharmaceutical drug discovery and development, biochemistry, clinical analysis, environmental studies, and natural products research. Supported by the most relevant literature available, each chapter examines how the strategies, technologies, and recent advances—from sample pretreatment to data processing—in LC–MS helped to shape these disciplines. Featuring new chapters and extensive revisions throughout the book, Liquid Chromatography–Mass Spectrometry, Third Edition continues to provide scientists with a definitive guide and reference to the most important principles, strategies, and experimental precedents for applying LC–MS to their research.
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by: Robert P.
publisher: Allured Pub Corp, published: 2007-02-28
ASIN: 1932633219
EAN: 9781932633214
sales rank: 1253481
Now includes an additional 600 compounds, 2,205 compounds analyzed from their original sources, larger and easier to read mass spectra, occurrence nature information and 37% more content that the 2001 edition! This is the fourth edition on mass spectra and retention times of common components in plant essential oils. It differs from the previous editions in several important areas: 600 compounds have been added, the sources of origination for each compound are listed, the mass spectra are larger and easier to read, occurrence nature information is now included and all 2,205 compounds have been analyzed from their original sources on an HP5971 MSD mass spectrometer using HP Chemstation software. In addition, the library (including retention times) is now available for the most common mass spectrometer/computer systems.
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