Life science and biomedical books

Related books on 'dna-sequencing'

	From Genes to Genomes: Concepts and Applications of DNA Technology by: Jeremy W. Dale publisher: Wiley, published: 2012-02-14 ASIN: 0470683856 EAN: 9780470683859 sales rank: 105869 The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation. The new edition features: Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics. Clear, two-colour diagrams throughout. A dedicated website including all figures. Noted for its outstanding balance between clarity of coverage and level of detail, this book provides an excellent introduction to the fast moving world of molecular genetics.
	The $1,000 Genome: The Revolution in DNA Sequencing and the New Era of Personalized Medicine by: Kevin Davies publisher: Free Press, published: 2010-09-07 ASIN: B004KAB370 sales rank: 336546 In 2000, President Bill Clinton signaled the completion of the Human Genome Project at a cost in excess of $2 billion. A decade later, the price for any of us to order our own personal genome sequence—a comprehensive map of the 3 billion letters in our DNA—is rapidly and inevitably dropping to just $1,000. Dozens of men and women—scientists, entrepreneurs, celebrities, and patients—have already been sequenced, pioneers in a bold new era of personalized genomic medicine. The $1,000 genome has long been considered the tipping point that would open the floodgates to this revolution. Do you have gene variants associated with Alzheimer’s or diabetes, heart disease or cancer? Which drugs should you consider taking for various diseases, and at what dosage? In the years to come, doctors will likely be able to tackle all of these questions—and many more—by using a computer in their offices to call up your unique genome sequence, which will become as much a part of your medical record as your blood pressure. Indeed, many experts are advocating that all newborns have a complete genome analysis done so that preventive measures and preemptive medicine can begin early in life. How has this astonishing achievement been accomplished? And what will it mean for our lives? To research the story of this unfolding revolution, critically acclaimed science writer Kevin Davies has spent the past few years traveling to the leading centers and interviewing the entrepreneurs and pioneers in the race to achieve the $1,000 genome. He vividly brings to life the extraordinary drama of this grand scientific achievement, revealing the masterful ingenuity that has transformed the process of decoding DNA and delivering the information it possesses to the public at large. Davies also profiles the future of genomic medicine and thoughtfully explores the many pressing issues raised by the tidal wave of personal genetic information. Will your privacy be protected? Will you be pressured, by insurance companies or by your employer, to get your genome sequenced? What psychological toll might there be to discovering you are at risk for certain diseases like Alzheimer’s? And will the government or the medical establishment come between you and your genome? One thing that is not in question is that we are moving swiftly into the personalized medicine era, and The $1,000 Genome is an essential guide to this brave new future.
	Intelligent Intervention by: Robert Steven Thomas publisher: Dog Ear Publishing, LLC, published: 2011-12-23 ASIN: 1457507781 EAN: 9781457507786 sales rank: 590499 Erich von Daniken pioneered and Zecharia Sitchen introduced the world to the concept of Ancient Aliens in the early 1970s. Bauval, Hancock, Dunn, Collins, von Ward and others fleshed in the evidence during the 80's & 90's. In the 21st century it will be David Wilcock and Robert Steven Thomas who convince a critical mass of educated, open-minded people in the world the reality of mankind's true evolution in conjunction with advanced-alien assistance. "Intelligent Intervention" is a contemporary masterpiece. It pulls together all of the most compelling evidence that has been gathering (but ignored by the main-stream Establishment) into a single, comprehensive, accurate description of human history. It reads like science fiction but is science fact. After you complete this book your understanding of history will never be the same. Moreover, you'll come to understand how each one of us can personally contribute to create a kinder world and better future for all humanity. 544 pages; Illustrated; Non-fiction.
	Molecular Biology Techniques, Third Edition: A Classroom Laboratory Manual by: Sue Carson publisher: Academic Press, published: 2011-11-21 ASIN: 0123855446 EAN: 9780123855442 sales rank: 923088 This manual is an indispensable tool for introducing advanced undergraduates and beginning graduate students to the techniques of recombinant DNA technology, or gene cloning and expression. The techniques used in basic research and biotechnology laboratories are covered in detail. Students gain hands-on experience from start to finish in subcloning a gene into an expression vector, through purification of the recombinant protein. The second edition has been completely re-written, with new laboratory exercises and all new illustrations and text, designed for a typical 15-week semester, rather than a 4-week intensive course. The "project" approach to experiments was maintained: students still follow a cloning project through to completion, culminating in the purification of recombinant protein. It takes advantage of the enhanced green fluorescent protein-students can actually visualize positive clones following IPTG induction. *Cover basic concepts and techniques used in molecular biology research labs *Student-tested labs proven successful in a real classroom laboratories *Exercises simulate a cloning project that would be performed in a real research lab *"Project" approach to experiments gives students an overview of the entire process *Prep-list appendix contains necessary recipes and catalog numbers, providing staff with detailed instructions
	The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution by: Sean B. Carroll publisher: W. W. Norton & Company, published: 2007-09-17 ASIN: 0393330516 EAN: 9780393330519 sales rank: 54489 DNA evidence not only solves crimes—in Sean Carroll's hands it will now end the Evolution Wars. DNA is the genetic material that defines us as individuals. Over the last two decades, it has emerged as a powerful tool for solving crimes and determining guilt and innocence. But, very recently, an important new aspect of DNA has been revealed—it contains a detailed record of evolution. That is, DNA is a living chronicle of how the marvelous creatures that inhabit our planet have adapted to its many environments, from the freezing waters of the Antarctic to the lush canopy of the rain forest. In the pages of this highly readable narrative, Sean Carroll guides the general reader on a tour of the massive DNA record of three billion years of evolution to see how the fittest are made. And what a eye-opening tour it is—one featuring immortal genes, fossil genes, and genes that bear the scars of past battles with horrible diseases. This book clinches the case for evolution, beyond any reasonable doubt. 50 black-and-white illustrations and 8 pages of color
	Genome Organization And Function In The Cell Nucleus publisher: Wiley-VCH, published: 2012-02-01 ASIN: 3527326987 EAN: 9783527326983 sales rank: 1139445 By way of its clear and logical structure, as well as abundant high-resolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: replication, recombination, repair, and transcription. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.
	Fundamentals of Forensic DNA Typing by: John M. Butler publisher: Academic Press, published: 2009-09-03 ASIN: 0123749999 EAN: 9780123749994 sales rank: 132675 John Butler, bestselling author of Forensic DNA Typing, now applies his expertise on the subject of DNA analysis into an introductory textbook. Fundamentals of Forensic DNA Typing walks students step-by-step through the DNA analysis process beginning with collection of evidence at a crime scene to the statistical interpretation of the results. Also included are brief discussions of such news worthy topics as victim identification from the September 11, 2001 attacks, the identification of the remains of the Romanovs, the last Russian Royal family, and the O.J. Simpson case. New applications, such as genetic genealogy and tracing domestic pet hairs to perpetrators, are also detailed. With its clear and understandable style and extensive list of online ancillaries and study aids, this textbook will make the subject accessible to students in forensic science courses worldwide. Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key
	DNA Sequencing Protocols (Methods in Molecular Biology) publisher: Springer, published: 2012-03-31 ASIN: 1617371505 EAN: 9781617371509 sales rank: 11135111 Colin Graham and a team of leading investigators and expert clinical scientists update the acclaimed first edition with a collection of powerful, up-to-date PCR-based methods for DNA sequencing, many suitable for human genome sequencing and mutation detection in human disease. This second edition offers new material on automated DNA sequencers, capillary DNA sequencers, heterozygote mutation detection, web-based sequencing databases and genome sequencing sites, and the human genome project. State-of-the-art and highly practical, DNA Sequencing Protocols, 2nd Edn. constitutes an essential laboratory handbook for geneticists and molecular biologists, offering concise, easy-to-follow methods that will work and impact today's genome sequencing projects.
	Forensic DNA Typing, Second Edition: Biology, Technology, and Genetics of STR Markers by: John M. Butler Ph.D. (Analytical Chemistry) University of Virginia publisher: Academic Press, published: 2005-03-08 ASIN: 0121479528 EAN: 9780121479527 sales rank: 330883 Since the enormously successful first edition of Forensic DNA Typing was published, the Human Genome Project has published a draft sequence of the human genome and completed the "finished" reference sequence. The advent of modern DNA technology has resulted in the increased ability to perform human identity testing-desirable in a number of situations including the determination of perpetrators of violent crime such as murder and rape, resolving unestablished paternity, and identifying remains of missing persons or victims of mass disasters. The technology has been utilized in identifying remains from victims of the World Trade Center twin towers collapse following the terrorist attacks of September 11, 2001, the President Clinton-Monica Lewinsky scandal, and the identification of the remains in the Tomb of the Unknown Soldier. Indeed, our perceptions of history have been changed with DNA evidence that revealed Thomas Jefferson fathered a child by one of his slaves. This book examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century. *The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome *Chapters cover the topic from introductory level right up to "cutting edge" research *High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases *NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions
	Genetics For Dummies (For Dummies (Math & Science)) by: Tara Rodden Robinson publisher: For Dummies, published: 2010-05-03 ASIN: 0470551747 EAN: 9780470551745 sales rank: 19727 A plain-English guide to genetics Want to know more about genetics? This non-intimidating guide gets you up to speed on all the fundamentals and the most recent discoveries. Now with 25% new and revised material, Genetics For Dummies, 2nd Edition gives you clear and accessible coverage of this rapidly advancing field. From dominant and recessive inherited traits to the DNA double-helix, you get clear explanations in easy-to-understand terms. Plus, you'll see how people are applying genetic science to fight disease, develop new products, solve crimes . . . and even clone cats. Covers topics in a straightforward and effective manner Includes coverage of stem cell research, molecular genetics, behavioral genetics, genetic engineering, and more Explores ethical issues as they pertain to the study of genetics Whether you?re currently enrolled in a genetics course or are just looking for a refresher, Genetics For Dummies, 2nd Edition provides science lovers of all skill levels with easy-to-follow information on this fascinating subject.

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