Related books on 'immunohistochemistry'

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by: David J. Dabbs MD
publisher: Saunders, published: 2010-01-29
ASIN: 1416057668
EAN: 9781416057666
sales rank: 226302

Diagnostic Immunohistochemistry presents the latest information and most reliable guidance on immunohistological diagnoses in surgical pathology. David J. Dabbs, MD and other leading experts bring you state-of-the-art coverage on genomic and theranostic applications, molecular anatomic pathology, immunocytology, Non-Hodgkin's lymphoma, and more. Additional features such as tables discussing antibody specifications, differential diagnosis boxes, ancillary anatomic molecular diagnostics, and full-color histological images ensure user-friendly coverage that makes key information easy to find and apply. The fully searchable text is also available online at expertconsult.com, along with a downloadable image bank and access to Path Consult. This concise and complete resource is today's indispensable guide to the effective use of immunohistochemical diagnosis.

  • Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses.
  • Presents chapters arranged by organ system for comprehensive coverage of all relevant information in a convenient and intuitive organization.
  • Provides quick reference graphs for antibodies throughout the text that illustrate the frequency of immunostaining for a variety of antibodies in tumors.
  • Includes Key Diagnostic Points boxes in every chapter for a quick summary of text areas that are of particular importance.
  • Features an expert author for each chapter to ensure coverage of the current state of the art.
  • Includes access to the full text online at expertconsult.com, along with a downloadable image bank and Path Consult.
  • Provides guidance on the role of genomics in identifying genetic and molecular aspects of disease that may affect patient care and therapeutic approaches.
  • Covers theranostic applications to enable you to evaluate therapeutic choices based on immunohistochemical results.
  • Reflects the latest developments in the field through new chapters on molecular anatomic pathology and immunocytology, as well as updated chapters on immunohistology of the prostate, bladder, testis, and kidney and Non-Hodgkin's lymphoma.
  • Discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval.
  • Presents key differential diagnoses boxes that provide tabular summaries of DDx and algorithms.
  • Features discussions of ancillary anatomic molecular diagnostics as an adjunct to immunohistochemistry for a more well-rounded diagnostic approach.

Accurately interpret immunohistochemical results and provide the clinician with the best therapeutic approaches for the patient

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publisher: Springer, published: 2011-07-01
ASIN: 144198061X
EAN: 9781441980618
sales rank: 234574
In a conceptually current, quick-reference, Question & Answer format, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions provides standardization of the immunostaining process for each antibody and for each staining panel. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 5,000 tumors to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. Chapters are presented in a unique Question and Answer format. One table/IHC panel is provided to address each question. A concise explanatory note follows each table/panel to avoid diagnostic pitfalls. Website links are provided throughout to update the massive information in this field, providing the most current knowledge and the potential for live expert consultation. All chapters are written by nationally/internationally recognized experts in the related area ensuring authority and excellence. Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

by: Igor B. Buchwalow
publisher: Springer, published: 2010-02-05
ASIN: 3642046088
EAN: 9783642046087
sales rank: 578015
While many excellent texts and monographs exist which cover various aspects of immunohistochemistry, the lack of a concise comprehensive guide to using the field’s methods was a major motivation for the authors to write this book. The authors carefully selected the methods and easy-to-adopt protocols discussed. In addition to estabished techniques, special attention was paid to current developments in immunohistochemistry such as antigen retrieval, signal amplification, the use of epitope tags, multiple immunolabeling, and diagnostic immunohistochemistry. All procedures examined have been tested by the authors; many are routinely used in daily practice in their institute. Each chapter starts with a short introduction to the respective method’s underlying principles before presenting step-by-step protocols and instructions, including precise recipes for all materials needed. Thus, the book is suitable for a broad audience, ranging from students and technical assistants to experienced researchers.

by: David J. Dabbs MD
publisher: Churchill Livingstone, published: 2002-01-15
ASIN: 0443065667
EAN: 9780443065668
sales rank: 650317
17 world-renowned experts offer the most current information and reliable guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. Introductory chapters cover cost modeling for immunohistochemistry and immunohistochemical techniques. The following chapters utilize an organ systems and diseases approach to diagnostic tumor pathology.

by: Tsieh Sun MD
publisher: Lippincott Williams & Wilkins, published: 2011-11-17
ASIN: 1608316165
EAN: 9781608316168
sales rank: 670573
Immunophenotyping is the most powerful tool in the routine diagnosis of hematologic neoplasms. Immunohistochemical technique is used in histology labs for this purpose, while flow cytometry is used in clinical labs. While separately these 2 techniques are very useful in detecting lymphomas and leukemias, the combination of both creates a very powerful and definitive diagnostic tool. The addition of molecular genetics to the book will make it an all-encompassing reference text.

by: Peiguo Chu
publisher: Cambridge University Press, published: 2009-04-27
ASIN: 0521874300
EAN: 9780521874304
sales rank: 950412
Diagnostic pathology is an inherently flawed science due to the many possible interpretations of various tissues. However, the application of immunohistochemical stains as a diagnostic tool has been widely used since the 1990s as an extremely effective ancillary technique that removes much subjectivity from the practice. In fact, immunohistochemistry has supplanted simple morphologic evaluation as the definitive diagnostic method for a wide array of tumor types. This book offers a new and modern atlas-based resource for this science. Every anatomic region is covered in detail, and major diseases contain side-by-side examples of other ancillary staining techniques for comparison. The text is geared toward both the resident and practitioner of anatomic pathology and is supplemented with histograms, algorithms, and guides to the application and interpretation of uncommon antigens and immunostains. Not only is the book illustrated with more than 600 high-quality photomicrographs, but a companion CD-ROM of all images in downloadable format is included.

publisher: Scion Publishing Ltd., published: 2007-01-20
ASIN: 1904842038
EAN: 9781904842033
sales rank: 1275484
Immunohistochemistry has long been a cornerstone technique in biomedical research, but there have been major new developments in recent years, including a growing trend towards automation and high throughput technology. These new techniques, often coupled with some of the established methodology, have seen an expanding range of applications. Immunohistochemistry: Methods Express is a comprehensive research guide that describes both the key new techniques and more established methods. Every chapter discusses the merits and limitations of the various approaches and then provides selected tried-and-tested protocols, as well as a plethora of good practical advice, for immediate use at the bench. This book is an essential laboratory manual for all life science researchers who use immunochemistry. It is a book which both experienced researchers and those new to the field will find invaluable.

by: David Dabbs
publisher: Churchill Livingstone, published: 2006-02-10
ASIN: 0443066523
EAN: 9780443066528
sales rank: 1144775
The New Edition of this popular text features world-renowned experts who offer the most current information and reliable guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. The book is organized in a consistent format of organ systems, specifically designed to target diagnostic dilemmas in surgical pathology. Each chapter features an introduction and a systematic approach to the diagnostic entities of that organ system. Readers will also find easy-to-understand diagnostic algorithms and "immunohistograms" that depict immunostaining patterns of tumors, as well as charts, tables, and high-quality color histologic images that assist in making a definitive diagnosis.
  • Consistently organized chapters offer an introduction to the subject · a discussion of the biology of the relevant antigens and antibodies · a literature review · and numerous diagnostic algorithms and immunohistograms.
  • Provides all the information readers need on a specific topic and eliminates the need to reference multiple areas of the text.
  • Includes quick- reference boxes at the end of each section that summarize the most important diagnostic points.
  • Provides separate method sections for diagnostic surgical pathology and immunocytology supply reference materials for the performance of diagnostic immunohistochemical tests.
  • Features color photographs and illustrations that highlight key diagnostic points.
  • Features updated and expanded antibody tables as well as the newest data on existing antibodies.
  • Incorporates more hematopoietic markers.
  • Presents key diagnostic points in each section that highlight the most pertinent aspects of that section and serve as a quick reference.
  • Discusses potential diagnostic pitfalls and offers immunohistologic differential diagnosis where relevant.


With 32 additional contributors.

publisher: Humana Press, published: 2011-02-14
ASIN: 1617790230
EAN: 9781617790232
sales rank: 1889366
Unlike detecting constitutively expressed targets, immunohistochemical detection of labile, low abundance, and short-lived signal transduction molecules can be a very difficult task.  In Signal Transduction Immunohistochemistry: Methods and Protocols, IHC experts contribute detailed protocols addressing the numerous challenges of signal-transduction immunohistochemistry (ST-IHC).  Beginning with a set of introductory chapters, the volume moves on to cover techniques used for the preservation of antigens and their unmasking, protocols in digital imaging and image analysis of stained cells and tissues, high-throughput data collection and data analysis, and techniques used in neuroscience as well as cancer and stem cell research.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Signal Transduction Immunohistochemistry: Methods and Protocols serves as an ideal guide for novices and as a bastion of inspiring ideas to be exploited by experienced researchers on the lookout for new experimental tricks and hints.

by: M.A. Hayat
publisher: Springer, published: 2002-06-30
ASIN: 0306467704
EAN: 9780306467707
sales rank: 2266979
Histochemistry deals with the activities of chemical components in cells, and immunohistochemistry addresses the function of cell types in tissue or organs, such as those leading to acceptance or rejection of grafts or organs. This book is a methods volume focusing on antigen retrieval, particularly methods used in disease-related antigens. Because the book is a methods volume and a lab manual, it will have an audience of pathologists, biochemists, and lab technicians.
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