mass-spectrometry books

Related books on 'mass-spectrometry'

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Mass Spectrometry: Principles and Applications

by: Edmond de Hoffmann
publisher: Wiley-Interscience, published: 2007-11-20
ASIN: 0470033118
EAN: 9780470033111
sales rank: 175805
The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra.
This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications.
Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.

Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation

by: J. Throck Watson
publisher: Wiley, published: 2007-12-04
ASIN: 0470516348
EAN: 9780470516348
sales rank: 431346
Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references.
This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry

Fundamentals of Contemporary Mass Spectrometry (Wiley - Interscience Series on Mass Spectrometry)

by: Chhabil Dass
publisher: Wiley-Interscience, published: 2007-04-20
ASIN: 0471682292
EAN: 9780471682295
sales rank: 326499
Modern mass spectrometry - the instrumentation and applications in diverse fields
Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers:
Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques
Organic and inorganic mass spectrometry
Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials
Applications to quantitative analysis
Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included.
This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.

Electrospray and MALDI Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications

publisher: Wiley, published: 2010-04-26
ASIN: 0471741078
EAN: 9780471741077
sales rank: 668268
Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas
Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research.
Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts:
Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware
Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces
Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers
Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra
Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery
Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.

A Beginner's Guide to Mass Spectral Interpretation

by: Terrence A. Lee
publisher: Wiley, published: 1998-01-15
ASIN: 0471976296
EAN: 9780471976295
sales rank: 642484
This book is a logical, step-by-step guide to identification of organic compounds by mass spectrometry. The book is organized into chapters covering the major types of organic compounds, including alcohols, acids and esters, aldehydes and ketones, ethers, hydrocarbons, halogenated compounds, amines and amides, and sulfur-containing compounds. In each chapter, the mechanisms of the major fragmentation pathways are discussed, with reference to several simple sample compounds. By teaching the user to recognize typical fragmentations, the book removes the need to search databases, often limited, of electronic spectra. Key features of the book include:
* 200 representative spectra of common organic compounds
* Functional group approach to mass spectra interpretation
* Appendix of 'unknown' spectra with step-by-step guide to identification
This book is a must for anyone who needs to identify organic molecules by mass spectrometry but does not need to know the detailed workings of a mass spectrometer.

Quadrupole Mass Spectrometry and Its Applications (AVS Classics in Vacuum Science and Technology)

publisher: American Inst. of Physics, published: 1997-05-09
ASIN: 1563964554
EAN: 9781563964558
sales rank: 735827
Market: Those involved in laboratory chemical analysis, atmospheric chemistry, and atomic and molecular physics. Long regarded as the standard introduction to the field, Quadrupole Mass Spectrometry and Its Applications provides today's engineers and scientists with an authoritative, wide-ranging overview of the development and uses of quadrupoles. Beginning with the basic operating principles of quadrupole devices, the book moves from general explanations of the actions of radio-frequency fields to descriptions of their utilization in quadrupole mass filters, monopoles, three-dimensional quadrupole ion traps, and various time-of -flight spectrometers. A concluding series of chapters examines fundamental applications of quadrupoles in atomic and subatomic physics, gas chromatography, upper atmospheric research, medicine, and environmental studies.

Inductively Coupled Plasma-Mass Spectrometry: Practices and Techniques

by: Howard E. Taylor
publisher: Academic Press, published: 2000-10-31
ASIN: 0126838658
EAN: 9780126838657
sales rank: 566574
Inductively Coupled Plasma-Mass Spectrometry presents a concise A-Z description of inductively coupled plasma-mass spectrometry, written in layman's terms, for use in the solution of trace element analytical chemistry problems. Detailed discussion of sample introduction and data interpretation is provided.

Practicing analytical chemists will be able to use this text to familiarize themselves with the principles, approaches, options, pitfalls, and advantages of ICP-MS technology.

Key Features
* Concise and straightforward descriptions of ICP-MS principles and instrumentation, ensuring rapid understanding of the technique and its advantages and limitations
* Examples to clarify the operational characteristics of the technology
* Drawings and illustrations to clarify principles, techniques, and methodology
* Discussions of practical approaches to the solution of specific trace analysis problems with helpful tips on efficiently producing the most accurate and precise data
* Easy-to-understand terms, so that new users of the technology will immediately benefit from the information provided
* Comprehensive appendixes containing isotopic and interference data
* An exhaustive compilation of literature citations for supplemental information

Trace Quantitative Analysis by Mass Spectrometry

by: Robert K. Boyd
publisher: Wiley, published: 2008-06-11
ASIN: 0470057718
EAN: 9780470057711
sales rank: 862005
This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry:
Covers all aspects of the use of mass spectrometry for quantitation purposes
Written in textbook style to facilitate understanding of this topic
Presents fundamentals and real-world examples in a ‘learning-though-doing’ style

Mass Spectrometry: A Textbook

by: Jürgen H. Gross
publisher: Springer, published: 2011-04-06
ASIN: 3642107095
EAN: 9783642107092
sales rank: 337496
This book offers a balanced mixture of practice-oriented information and theoretical background as well as numerous references, clear illustrations, and useful data tables. Problems and solutions are accessible via a special website. This new edition has been completely revised and extended; it now includes three new chapters on tandem mass spectrometry, interfaces for sampling at atmospheric pressure, and inorganic mass spectrometry.

Liquid Chromatography-Mass Spectrometry, Third Edition (Chromatographic Science Series)

by: Wilfried M.A. Niessen
publisher: CRC Press, published: 2006-08-09
ASIN: 0824740823
EAN: 9780824740825
sales rank: 1642402
A constructive evaluation of the most significant developments in liquid chromatography–mass spectrometry (LC–MS) and its uses for quantitative bioanalysis and characterization for a diverse range of disciplines, Liquid Chromatography–Mass Spectrometry, Third Edition offers a well-rounded coverage of the latest technological developments and applications.
As the technology itself has matured into a reliable analytical method over the last 15 years, the most exciting developments occur in LC–MS augments research into new applications. This edition places a stronger emphasis than previous editions on the impact of LC–MS methods, dedicating two-thirds of the text to small-molecule and biomolecular applications such as proteomics, pharmaceutical drug discovery and development, biochemistry, clinical analysis, environmental studies, and natural products research. Supported by the most relevant literature available, each chapter examines how the strategies, technologies, and recent advances—from sample pretreatment to data processing—in LC–MS helped to shape these disciplines.
Featuring new chapters and extensive revisions throughout the book, Liquid Chromatography–Mass Spectrometry, Third Edition continues to provide scientists with a definitive guide and reference to the most important principles, strategies, and experimental precedents for applying LC–MS to their research.

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	Mass Spectrometry: Principles and Applications by: Edmond de Hoffmann publisher: Wiley-Interscience, published: 2007-11-20 ASIN: 0470033118 EAN: 9780470033111 sales rank: 175805 The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications. Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.
	Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation by: J. Throck Watson publisher: Wiley, published: 2007-12-04 ASIN: 0470516348 EAN: 9780470516348 sales rank: 431346 Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry
	Fundamentals of Contemporary Mass Spectrometry (Wiley - Interscience Series on Mass Spectrometry) by: Chhabil Dass publisher: Wiley-Interscience, published: 2007-04-20 ASIN: 0471682292 EAN: 9780471682295 sales rank: 326499 Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.
	Electrospray and MALDI Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications publisher: Wiley, published: 2010-04-26 ASIN: 0471741078 EAN: 9780471741077 sales rank: 668268 Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.
	A Beginner's Guide to Mass Spectral Interpretation by: Terrence A. Lee publisher: Wiley, published: 1998-01-15 ASIN: 0471976296 EAN: 9780471976295 sales rank: 642484 This book is a logical, step-by-step guide to identification of organic compounds by mass spectrometry. The book is organized into chapters covering the major types of organic compounds, including alcohols, acids and esters, aldehydes and ketones, ethers, hydrocarbons, halogenated compounds, amines and amides, and sulfur-containing compounds. In each chapter, the mechanisms of the major fragmentation pathways are discussed, with reference to several simple sample compounds. By teaching the user to recognize typical fragmentations, the book removes the need to search databases, often limited, of electronic spectra. Key features of the book include: * 200 representative spectra of common organic compounds * Functional group approach to mass spectra interpretation * Appendix of 'unknown' spectra with step-by-step guide to identification This book is a must for anyone who needs to identify organic molecules by mass spectrometry but does not need to know the detailed workings of a mass spectrometer.
	Quadrupole Mass Spectrometry and Its Applications (AVS Classics in Vacuum Science and Technology) publisher: American Inst. of Physics, published: 1997-05-09 ASIN: 1563964554 EAN: 9781563964558 sales rank: 735827 Market: Those involved in laboratory chemical analysis, atmospheric chemistry, and atomic and molecular physics. Long regarded as the standard introduction to the field, Quadrupole Mass Spectrometry and Its Applications provides today's engineers and scientists with an authoritative, wide-ranging overview of the development and uses of quadrupoles. Beginning with the basic operating principles of quadrupole devices, the book moves from general explanations of the actions of radio-frequency fields to descriptions of their utilization in quadrupole mass filters, monopoles, three-dimensional quadrupole ion traps, and various time-of -flight spectrometers. A concluding series of chapters examines fundamental applications of quadrupoles in atomic and subatomic physics, gas chromatography, upper atmospheric research, medicine, and environmental studies.
	Inductively Coupled Plasma-Mass Spectrometry: Practices and Techniques by: Howard E. Taylor publisher: Academic Press, published: 2000-10-31 ASIN: 0126838658 EAN: 9780126838657 sales rank: 566574 Inductively Coupled Plasma-Mass Spectrometry presents a concise A-Z description of inductively coupled plasma-mass spectrometry, written in layman's terms, for use in the solution of trace element analytical chemistry problems. Detailed discussion of sample introduction and data interpretation is provided. Practicing analytical chemists will be able to use this text to familiarize themselves with the principles, approaches, options, pitfalls, and advantages of ICP-MS technology. Key Features * Concise and straightforward descriptions of ICP-MS principles and instrumentation, ensuring rapid understanding of the technique and its advantages and limitations * Examples to clarify the operational characteristics of the technology * Drawings and illustrations to clarify principles, techniques, and methodology * Discussions of practical approaches to the solution of specific trace analysis problems with helpful tips on efficiently producing the most accurate and precise data * Easy-to-understand terms, so that new users of the technology will immediately benefit from the information provided * Comprehensive appendixes containing isotopic and interference data * An exhaustive compilation of literature citations for supplemental information
	Trace Quantitative Analysis by Mass Spectrometry by: Robert K. Boyd publisher: Wiley, published: 2008-06-11 ASIN: 0470057718 EAN: 9780470057711 sales rank: 862005 This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding of this topic Presents fundamentals and real-world examples in a ‘learning-though-doing’ style
	Mass Spectrometry: A Textbook by: Jürgen H. Gross publisher: Springer, published: 2011-04-06 ASIN: 3642107095 EAN: 9783642107092 sales rank: 337496 This book offers a balanced mixture of practice-oriented information and theoretical background as well as numerous references, clear illustrations, and useful data tables. Problems and solutions are accessible via a special website. This new edition has been completely revised and extended; it now includes three new chapters on tandem mass spectrometry, interfaces for sampling at atmospheric pressure, and inorganic mass spectrometry.
	Liquid Chromatography-Mass Spectrometry, Third Edition (Chromatographic Science Series) by: Wilfried M.A. Niessen publisher: CRC Press, published: 2006-08-09 ASIN: 0824740823 EAN: 9780824740825 sales rank: 1642402 A constructive evaluation of the most significant developments in liquid chromatography–mass spectrometry (LC–MS) and its uses for quantitative bioanalysis and characterization for a diverse range of disciplines, Liquid Chromatography–Mass Spectrometry, Third Edition offers a well-rounded coverage of the latest technological developments and applications. As the technology itself has matured into a reliable analytical method over the last 15 years, the most exciting developments occur in LC–MS augments research into new applications. This edition places a stronger emphasis than previous editions on the impact of LC–MS methods, dedicating two-thirds of the text to small-molecule and biomolecular applications such as proteomics, pharmaceutical drug discovery and development, biochemistry, clinical analysis, environmental studies, and natural products research. Supported by the most relevant literature available, each chapter examines how the strategies, technologies, and recent advances—from sample pretreatment to data processing—in LC–MS helped to shape these disciplines. Featuring new chapters and extensive revisions throughout the book, Liquid Chromatography–Mass Spectrometry, Third Edition continues to provide scientists with a definitive guide and reference to the most important principles, strategies, and experimental precedents for applying LC–MS to their research.