monoclonal-antibody books

Related books on 'monoclonal-antibody'

Return to life science book list
Number of products: 24894
Page 1 of 2490

Therapeutic Monoclonal Antibodies: From Bench to Clinic

publisher: Wiley, published: 2009-10-12
ASIN: 0470117915
EAN: 9780470117910
sales rank: 318261

70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies.
First book to address the discovery and development of antibody therapeutics in their entirety.
Most chapters contain experimental data to illustrate the principles described in them.
Authors provide detailed methodologies that readers can take away with them and use in their own laboratories

Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer

publisher: Wiley, published: 2010-08-09
ASIN: 0470243724
EAN: 9780470243725
sales rank: 408576
Oncology Book of 2011, British Medical Association's Medical Book Awards
Awarded first prize in the Oncology category at the 2011 BMA Medical Book Awards, Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer helps readers understand this hot pharmaceutical field with up-to-date developments. Expert discussion covers a range of diverse topics associated with this field, including the optimization of design of biomolecules and radiochemistry, cell and animal models for preclinical evaluation, discoveries from key clinical trials, radiation biology and dosimetry, and considerations in regulatory approval. With chapters authored by internationally renowned experts, this book delivers a wealth of information to push future discovery.

Process Scale Purification of Antibodies

publisher: Wiley-Interscience, published: 2009-02-09
ASIN: 0470209623
EAN: 9780470209622
sales rank: 538048
Traditional column chromatography dominates current purification technology, and many of the productivity gains that have been achieved have relied on upscaling such devices. However, this comes with a cost penalty and the pharmaceutical industry has reached the point at which further upscaling becomes economically unsupportable. This book offers a broad-based reassessment of old and new purification methods, incorporating an analysis of innovative new trends in purification. The book has wide coverage of different antibody purification strategies and brings together top-tier experts to address problems in process-scale antibody purification.

Current Trends in Monoclonal Antibody Development and Manufacturing (Biotechnology: Pharmaceutical Aspects)

publisher: Springer, published: 2009-11-12
ASIN: 0387766421
EAN: 9780387766423
sales rank: 1116505
Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups involved in the development of this important class of molecules, monoclonal antibodies products will become increasingly prevalent over the next decade. Recently the regulatory review of monoclonal antibodies has been moved from Center for Biologics and Research to the Center for Drug Evaluation and Research (CDER) division of the US Food and Drug Administration. It is anticipated that CDER will expect a certain minimal amount of data to be provided as more of these products move through the regulatory pipeline. Current Trends in Monoclonal Antibody Development and Manufacturing will provide readers with an understanding of what is currently being done in the industry to develop, manufacture, and release monoclonal antibody products and what will be required for a successful regulatory submission.

Applications And Engineering Of Monoclonal Antibodies

by: David J. King
publisher: CRC Press, published: 1998-12
ASIN: 0748404236
EAN: 9780748404230
sales rank: 4842916
A valuable resource for researchers and workers in the fields of both pharmaceuticals and biotechnology as well as undergraduates in biochemistry, applied biology, biomedical sciences and pharmacy, this book compares established techniques of antibody production with the new. Antibody structure and the implications of antibody engineering are fully discussed, and a case study approach illustrates how antibodies are finding increasing use in the diagnosis and treatment of disease. The volume ends with commercial expression, purification and large-scale manufacture of antibodies and their future potential, particularly as therapeutic agents.

Protein Purification: Principles and Practice

by: Robert K. Scopes
publisher: Springer, published: 1993-11-19
ASIN: 0387940723
EAN: 9780387940724
sales rank: 373383

The third edition of this classic guide to protein purification updates methods, principles and references. As in the widely-acclaimed earlier editions, Scopes guides both the novice and the experienced researcher from theory to application. Using the book, the reader is able to integrate methods effectively into optimum protocols for the task at hand.

Reviews of earlier editions:

"good practical advice that is presented in a pleasantly readable form" --Analytical Biochemistry

"well organized and written clearly" --American Scientist

"should be on every laboratory shelf where protein are being handled or purified...a feast and a genuine pleasure to read" --Nature

Monoclonal Antibodies, Third Edition: Principles and Practice

by: James W. Goding
publisher: Academic Press, published: 1996-03-19
ASIN: 0122870239
EAN: 9780122870231
sales rank: 1602000
Monoclonal Antibodies now have applications in virtually all areas of biology and medicine, and much of the world's biotechnology industry has its foundations in the exploitation of this technology.
The Third Edition of this well established book meets the needs of both newcomers to the area and experienced researchers, by providing an integrated treatment of both the production and application of monoclonal antibodies. As in previous editions, detailed and critical accounts of the theory, production, purification, fragmentation, storage and radiolabelling of monoclonal antibodies are given, along with descriptions of their use in antigen characterization, affinity chromatography and immunofluorescence. The present volume has been comprehensively updated to cover recent rapid advances, particularly with respect to the applications of molecular biology, the use of antibodies in closing and heterologous expression of genes, immunohistology and phage display libraries. Since the previous edition, there has been a growing trend towards the replacement of procedures using radioactive isotopes, and the current edition incorporates these newer technologies.
The text is oriented towards problems solving, and makes it easy to adapt each procedure to individual needs. Extensive cross-referencing, a glossary and a comprehensive index make this book an essential reference.
This book will be vital both for laboratories already producing or using monoclonal antibodies, and for workers in many disciplines who are contemplating their use.

*
* Provides an integrated treatment of both the production and application of monoclonals in cell biology, biochemistry, and immunology.
* Gives detailed and critical accounts of the theory, production, purification, storage, and relabelling of monoclonals, and their use in antigen characterization, affinity chromorography, and immunofluroscence.
* Comprehensively updated to cover the rapid advances that have occurred since the publication of the Second Edition.

Monoclonal Antibodies: Methods and Protocols (Methods in Molecular Biology)

publisher: Humana Press, published: 2010-11-19
ASIN: 1617376469
EAN: 9781617376467
sales rank: 3008614
This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins. This field will continue to expand and provide new and innovative techniques in the laboratory and as a basis that complements targeted therapy.

Purification Tools for Monoclonal Antibodies

by: Pete Gagnon
publisher: Validated Biosystems Inc, published: 1996-01-31
ASIN: 0965351599
EAN: 9780965351591
sales rank: 2460498

Monoclonal Antibodies in Biotechnology: Theoretical and Practical Aspects (Cambridge Studies in Biotechnology)

by: Kenneth C. McCullough
publisher: Cambridge University Press, published: 1990-04-27
ASIN: 0521258901
EAN: 9780521258906
sales rank: 4448671
This volume provides a complete description of the principles, methodologies and applications of monoclonal antibodies, one of the most exciting developments to occur in biotechnology in recent years, and a powerful technology for modern industry and science. The immune system and the role of the antibody are described and full details are given on how the hybridomas are formed, isolated, and maintained in culture such that the required antibody can be produced to a high degree of purity. The authors describe all the methodologies involved, all the reagents and solutions and all the assay conditions required for their production. The material is presented to enable research and development managers to make choices as to which are the most suitable techniques for their requirements. The book is comprehensively referenced, and will be a necessary resource for all those who are involved with this technology.

Page: 1 2 > 2490

Language for page:
Which server:
Operation:
Product category:
Search parameter:
Search Books:

	Therapeutic Monoclonal Antibodies: From Bench to Clinic publisher: Wiley, published: 2009-10-12 ASIN: 0470117915 EAN: 9780470117910 sales rank: 318261 70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies. First book to address the discovery and development of antibody therapeutics in their entirety. Most chapters contain experimental data to illustrate the principles described in them. Authors provide detailed methodologies that readers can take away with them and use in their own laboratories
	Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer publisher: Wiley, published: 2010-08-09 ASIN: 0470243724 EAN: 9780470243725 sales rank: 408576 Oncology Book of 2011, British Medical Association's Medical Book Awards Awarded first prize in the Oncology category at the 2011 BMA Medical Book Awards, Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer helps readers understand this hot pharmaceutical field with up-to-date developments. Expert discussion covers a range of diverse topics associated with this field, including the optimization of design of biomolecules and radiochemistry, cell and animal models for preclinical evaluation, discoveries from key clinical trials, radiation biology and dosimetry, and considerations in regulatory approval. With chapters authored by internationally renowned experts, this book delivers a wealth of information to push future discovery.
	Process Scale Purification of Antibodies publisher: Wiley-Interscience, published: 2009-02-09 ASIN: 0470209623 EAN: 9780470209622 sales rank: 538048 Traditional column chromatography dominates current purification technology, and many of the productivity gains that have been achieved have relied on upscaling such devices. However, this comes with a cost penalty and the pharmaceutical industry has reached the point at which further upscaling becomes economically unsupportable. This book offers a broad-based reassessment of old and new purification methods, incorporating an analysis of innovative new trends in purification. The book has wide coverage of different antibody purification strategies and brings together top-tier experts to address problems in process-scale antibody purification.
	Current Trends in Monoclonal Antibody Development and Manufacturing (Biotechnology: Pharmaceutical Aspects) publisher: Springer, published: 2009-11-12 ASIN: 0387766421 EAN: 9780387766423 sales rank: 1116505 Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups involved in the development of this important class of molecules, monoclonal antibodies products will become increasingly prevalent over the next decade. Recently the regulatory review of monoclonal antibodies has been moved from Center for Biologics and Research to the Center for Drug Evaluation and Research (CDER) division of the US Food and Drug Administration. It is anticipated that CDER will expect a certain minimal amount of data to be provided as more of these products move through the regulatory pipeline. Current Trends in Monoclonal Antibody Development and Manufacturing will provide readers with an understanding of what is currently being done in the industry to develop, manufacture, and release monoclonal antibody products and what will be required for a successful regulatory submission.
	Applications And Engineering Of Monoclonal Antibodies by: David J. King publisher: CRC Press, published: 1998-12 ASIN: 0748404236 EAN: 9780748404230 sales rank: 4842916 A valuable resource for researchers and workers in the fields of both pharmaceuticals and biotechnology as well as undergraduates in biochemistry, applied biology, biomedical sciences and pharmacy, this book compares established techniques of antibody production with the new. Antibody structure and the implications of antibody engineering are fully discussed, and a case study approach illustrates how antibodies are finding increasing use in the diagnosis and treatment of disease. The volume ends with commercial expression, purification and large-scale manufacture of antibodies and their future potential, particularly as therapeutic agents.
	Protein Purification: Principles and Practice by: Robert K. Scopes publisher: Springer, published: 1993-11-19 ASIN: 0387940723 EAN: 9780387940724 sales rank: 373383 The third edition of this classic guide to protein purification updates methods, principles and references. As in the widely-acclaimed earlier editions, Scopes guides both the novice and the experienced researcher from theory to application. Using the book, the reader is able to integrate methods effectively into optimum protocols for the task at hand. Reviews of earlier editions: "good practical advice that is presented in a pleasantly readable form" --Analytical Biochemistry "well organized and written clearly" --American Scientist "should be on every laboratory shelf where protein are being handled or purified...a feast and a genuine pleasure to read" --Nature
	Monoclonal Antibodies, Third Edition: Principles and Practice by: James W. Goding publisher: Academic Press, published: 1996-03-19 ASIN: 0122870239 EAN: 9780122870231 sales rank: 1602000 Monoclonal Antibodies now have applications in virtually all areas of biology and medicine, and much of the world's biotechnology industry has its foundations in the exploitation of this technology. The Third Edition of this well established book meets the needs of both newcomers to the area and experienced researchers, by providing an integrated treatment of both the production and application of monoclonal antibodies. As in previous editions, detailed and critical accounts of the theory, production, purification, fragmentation, storage and radiolabelling of monoclonal antibodies are given, along with descriptions of their use in antigen characterization, affinity chromatography and immunofluorescence. The present volume has been comprehensively updated to cover recent rapid advances, particularly with respect to the applications of molecular biology, the use of antibodies in closing and heterologous expression of genes, immunohistology and phage display libraries. Since the previous edition, there has been a growing trend towards the replacement of procedures using radioactive isotopes, and the current edition incorporates these newer technologies. The text is oriented towards problems solving, and makes it easy to adapt each procedure to individual needs. Extensive cross-referencing, a glossary and a comprehensive index make this book an essential reference. This book will be vital both for laboratories already producing or using monoclonal antibodies, and for workers in many disciplines who are contemplating their use. * * Provides an integrated treatment of both the production and application of monoclonals in cell biology, biochemistry, and immunology. * Gives detailed and critical accounts of the theory, production, purification, storage, and relabelling of monoclonals, and their use in antigen characterization, affinity chromorography, and immunofluroscence. * Comprehensively updated to cover the rapid advances that have occurred since the publication of the Second Edition.
	Monoclonal Antibodies: Methods and Protocols (Methods in Molecular Biology) publisher: Humana Press, published: 2010-11-19 ASIN: 1617376469 EAN: 9781617376467 sales rank: 3008614 This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins. This field will continue to expand and provide new and innovative techniques in the laboratory and as a basis that complements targeted therapy.
	Purification Tools for Monoclonal Antibodies by: Pete Gagnon publisher: Validated Biosystems Inc, published: 1996-01-31 ASIN: 0965351599 EAN: 9780965351591 sales rank: 2460498
	Monoclonal Antibodies in Biotechnology: Theoretical and Practical Aspects (Cambridge Studies in Biotechnology) by: Kenneth C. McCullough publisher: Cambridge University Press, published: 1990-04-27 ASIN: 0521258901 EAN: 9780521258906 sales rank: 4448671 This volume provides a complete description of the principles, methodologies and applications of monoclonal antibodies, one of the most exciting developments to occur in biotechnology in recent years, and a powerful technology for modern industry and science. The immune system and the role of the antibody are described and full details are given on how the hybridomas are formed, isolated, and maintained in culture such that the required antibody can be produced to a high degree of purity. The authors describe all the methodologies involved, all the reagents and solutions and all the assay conditions required for their production. The material is presented to enable research and development managers to make choices as to which are the most suitable techniques for their requirements. The book is comprehensively referenced, and will be a necessary resource for all those who are involved with this technology.