Life science and biomedical books

Related books on 'protein-structure'

	Introduction to Protein Structure by: Carl Branden publisher: Garland Science, published: 1999-01-03 ASIN: 0815323050 EAN: 9780815323051 sales rank: 156538 Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions.
	Proteins: Structure and Function by: David Whitford publisher: Wiley, published: 2005-05-23 ASIN: 0471498947 EAN: 9780471498940 sales rank: 362370 Proteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. Opening with a brief historical overview of the subject the book moves on to discuss the ‘building blocks’ of proteins and their respective chemical and physical properties. Later chapters explore experimental and computational methods of comparing proteins, methods of protein purification and protein folding and stability. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of Proteins.
	Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding by: Alan Fersht publisher: W. H. Freeman, published: 1998-09-15 ASIN: 0716732688 EAN: 9780716732686 sales rank: 312304 Fersht's Structure and Mechanism in Protein Science is a defining exploration of this new era, an expert depiction of the core principles of protein structure, activity, and mechanism as understood and applied today.  A thorough recasting of Fersht's previous text, the book takes a more general look at mechanisms in protein science, emphasizing the unity of concepts in folding and catalysis and the importance of the relationships between basic chemistry, kinetics, thermodynamics, and structure.
	Proteins: Structures and Molecular Properties by: Thomas E. Creighton publisher: W. H. Freeman, published: 1992-08-15 ASIN: 071677030X EAN: 9780716770305 sales rank: 198690 In one convenient resource, Creighton's landmark textbook offers an expert introduction to all aspects of proteins--biosynthesis, evolution, structures, dynamics, ligand binding, and catalysis.  It works equally well as a reference or as a classroom text.
	Introduction to Protein Science: Architecture, Function, and Genomics by: Arthur M. Lesk publisher: Oxford University Press, USA, published: 2010-05-20 ASIN: 0199541302 EAN: 9780199541300 sales rank: 149980 Designed for students in biology, biochemistry, and biomedicine, Introduction to Protein Science, Second Edition, provides a wide-ranging introduction to the contemporary study of proteins in health and disease. The text describes basic principles of protein structure and methods for studying them, illustrates the wide variety of functions that proteins have, and shows how their structures and functions are closely linked. Introduction to Protein Science, Second Edition, relates the study of proteins to the context of modern high-throughput data streams of genomics and proteomics. It also provides a balanced treatment of the relationship between computational and experimental methods. The text is enhanced by marginal notes, exercises, problems, and "weblems" that develop students' database and computational server skills. An updated and expanded Companion Website offers resources for students and instructors. New to this edition: * Coverage of new developments in the field, including high-throughput methods * A new chapter on enzyme kinetics * Extended treatments of such topics as protein evolution and the immune system * New pedagogical features including "key points" and "Proteins in Health and Disease" boxes * New end-of-chapter exercises, problems, and "weblems"
	Introduction to Proteins: Structure, Function, and Motion (Chapman & Hall/CRC Mathematical & Computational Biology) by: Amit Kessel publisher: CRC Press, published: 2010-12-17 ASIN: 1439810710 EAN: 9781439810712 sales rank: 163099 As the tools and techniques of structural biophysics assume greater roles in biological research and a range of application areas, learning how proteins behave becomes crucial to understanding their connection to the most basic and important aspects of life. With more than 350 color images throughout, Introduction to Proteins: Structure, Function, and Motion presents a unified, in-depth treatment of the relationship between the structure, dynamics, and function of proteins. Taking a structural–biophysical approach, the authors discuss the molecular interactions and thermodynamic changes that transpire in these highly complex molecules. The text incorporates various biochemical, physical, functional, and medical aspects. It covers different levels of protein structure, current methods for structure determination, energetics of protein structure, protein folding and folded state dynamics, and the functions of intrinsically unstructured proteins. The authors also clarify the structure–function relationship of proteins by presenting the principles of protein action in the form of guidelines. This comprehensive, color book uses numerous proteins as examples to illustrate the topics and principles and to show how proteins can be analyzed in multiple ways. It refers to many everyday applications of proteins and enzymes in medical disorders, drugs, toxins, chemical warfare, and animal behavior. Downloadable questions for each chapter are available at CRC Press Online.
	Fundamentals of Protein Structure and Function by: Engelbert Buxbaum publisher: Springer, published: 2007-09-18 ASIN: 0387263527 EAN: 9780387263526 sales rank: 922543 The textbook is clearly written, and is suitable for advanced students, e.g. during their master and PhD course time. It is very suited also for postdocs and young scientists as a textbook if they change fields in their research. The textbook represents a thorough and detailed description of the topics in each of the chapters. As the book selects very important topics of present fundamental research and relevant in medical biochemistry, it can supplement any of the text books in biochemistry and basic medicine already on the market. The textbook is clearly written, and is suitable for advanced students, e.g. during their master and PhD course time. It is very suited also for postdocs and young scientists as a textbook if they change fields in their research. The textbook represents a thorough and detailed description of the topics in each of the chapters. As the book selects very important topics of present fundamental research and relevant in medical biochemistry, it can supplement any of the text books in biochemistry and basic medicine already on the market.
	Proteases: Structure and Function publisher: Springer, published: 2012-07-29 ASIN: 3709108845 EAN: 9783709108840 Proteolysis is an irreversible posttranslational modification affecting each and every protein from its biosynthesis to its degradation. Limited proteolysis regulates targeting and activity throughout the lifetime of proteins. Balancing proteolysis is therefore crucial for physiological homeostasis. Control mechanisms include proteolytic maturation of zymogens resulting in active proteases and the shut down of proteolysis by counteracting endogenous protease inhibitors. Beyond the protein level, proteolytic enzymes are involved in key decisions during development that determine life and death – from single cells to adult individuals. In particular, we are becoming aware of the subtle role that proteases play in signaling events within proteolysis networks, in which the enzymes act synergistically and form alliances in a web-like fashion. Proteases come in different flavors. At least five families of mechanistically distinct enzymes and even more inhibitor families are known to date, many family members are still to be studied in detail. We have learned a lot about the diversity of the about 600 proteases in the human genome and begin to understand their physiological roles in the degradome. However, there are still many open questions regarding their actions in pathophysiology. It is in this area where the development of small molecule inhibitors as therapeutic agents is extremely promising. Approaching proteolysis as the most important, irreversible post-translational protein modification essentially requires an integrated effort of complementary research disciplines. In fact, proteolytic enzymes seem as diverse as the scientists working with these intriguing proteins. This book reflects the efforts of many in this exciting field of research where team and network formations are essential to move ahead.
	Fundamentals of Protein NMR Spectroscopy (Focus on Structural Biology) by: Gordon S. Rule publisher: Springer, published: 2005-12-19 ASIN: 1402034997 EAN: 9781402034992 sales rank: 618609 NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data processing. End of chapter exercises are included to emphasize important concepts. Fundamentals of Protein NMR Spectroscopy not only offer students a systematic, in-depth, understanding of modern NMR spectroscopy and its application to biomolecular systems, but will also be a useful reference for the experienced investigator.
	The Protein Power Lifeplan by: Michael R. Eades publisher: Grand Central Publishing, published: 2001-05 ASIN: 0446678678 EAN: 9780446678674 sales rank: 17686 The authors of Protein Power are back to advocate the "protein-rich, moderate-fat, carbohydrate-restricted diet" that opposes the high-carbohydrate, low-fat diet that every professional medical and dietetic organization (including those who have no diet books to sell) believes to be your best bet for avoiding heart disease, the number one killer. The authors insist, in the face of all this medical opposition, that "the whole idea that fat and cholesterol cause heart disease is just that: an idea." We're meant to be hunters, say the authors: bring on the meat. Let's go back to the Paleolithic diet (no mention of the brief life span of Paleolithic men and women).The Protein Power Lifeplan is not easy reading--most of the book is made up of scientific explanations, research summaries and interpretations, and nutritional warnings--but no recipes. Besides recommending eating protein and fat, the authors recommend sunbathing without sunblock (but "never, never let your skin burn!") and exercises such as "bringing home the buffalo" and "defending the camp." The authors admit that if you're trying to lose weight, you have to limit calories, but if you're not, you can "munch on nuts, seeds, nut butters, cheeses, jerky, guacamole, and olives all day long."Carbohydrates, say the authors, "are totally nonessential to your health and well-being"--words to make dieticians and cardiologists shudder.

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