Related books on 'protein-translation'
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by: Richard Durbin publisher: Cambridge University Press, published: 1998-05-13 ASIN: 0521629713 EAN: 9780521629713 sales rank: 167077 Probablistic models are becoming increasingly important in analyzing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analyzing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it is accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time presents the state of the art in this new and important field. |
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by: Arthur M. Lesk publisher: Oxford University Press, USA, published: 2010-05-20 ASIN: 0199541302 EAN: 9780199541300 sales rank: 173522 Designed for students in biology, biochemistry, and biomedicine, Introduction to Protein Science, Second Edition, provides a wide-ranging introduction to the contemporary study of proteins in health and disease. The text describes basic principles of protein structure and methods for studying them, illustrates the wide variety of functions that proteins have, and shows how their structures and functions are closely linked. Introduction to Protein Science, Second Edition, relates the study of proteins to the context of modern high-throughput data streams of genomics and proteomics. It also provides a balanced treatment of the relationship between computational and experimental methods. The text is enhanced by marginal notes, exercises, problems, and "weblems" that develop students' database and computational server skills. An updated and expanded Companion Website offers resources for students and instructors. New to this edition: * Coverage of new developments in the field, including high-throughput methods * A new chapter on enzyme kinetics * Extended treatments of such topics as protein evolution and the immune system * New pedagogical features including "key points" and "Proteins in Health and Disease" boxes * New end-of-chapter exercises, problems, and "weblems" |
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by: Amit Kessel publisher: CRC Press, published: 2010-12-17 ASIN: 1439810710 EAN: 9781439810712 sales rank: 185176 As the tools and techniques of structural biophysics assume greater roles in biological research and a range of application areas, learning how proteins behave becomes crucial to understanding their connection to the most basic and important aspects of life. With more than 350 color images throughout, Introduction to Proteins: Structure, Function, and Motion presents a unified, in-depth treatment of the relationship between the structure, dynamics, and function of proteins. Taking a structural–biophysical approach, the authors discuss the molecular interactions and thermodynamic changes that transpire in these highly complex molecules. The text incorporates various biochemical, physical, functional, and medical aspects. It covers different levels of protein structure, current methods for structure determination, energetics of protein structure, protein folding and folded state dynamics, and the functions of intrinsically unstructured proteins. The authors also clarify the structure–function relationship of proteins by presenting the principles of protein action in the form of guidelines. This comprehensive, color book uses numerous proteins as examples to illustrate the topics and principles and to show how proteins can be analyzed in multiple ways. It refers to many everyday applications of proteins and enzymes in medical disorders, drugs, toxins, chemical warfare, and animal behavior. Downloadable questions for each chapter are available at CRC Press Online. |
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by: Carl Branden publisher: Garland Science, published: 1999-01-03 ASIN: 0815323050 EAN: 9780815323051 sales rank: 178620 Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions. |
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publisher: Wiley-VCH, published: 2009-06-16 ASIN: 3527320741 EAN: 9783527320745 sales rank: 843413 From the leading author in the field, known around the world for his work and his authoritative publications, the contents of this book have been selected so as to reflect their relative importance for biopharmaceuticals. As a result, around half of the book is devoted to protein glycosylation, while the remainder is made up of other modifications, such as carboxylation, hydroxylation, sulfation, amidation and proteolytic processing. A final section addresses the latest trend of engineering the modification pattern to improve a given biopharmceutical, presenting several recent case studies of successful posttranslational engineering. This first authoritative overview of the topic is an indispensable guide for drug developers and drug manufacturers with an interest in protein pharmaceuticals. |
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publisher: Springer, published: 2010-10-29 ASIN: 1441924019 EAN: 9781441924018 The book that Sakamoto proposes along with Eric Ruben will be a comprehensive monograph on the role of protein modulation in cancer therapeutics; it will focus on targeting molecules that regulate protein stability in a variety of tumors. |
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by: John T. Moore publisher: Wiley Publishing, published: 2008-04-28 ASIN: 0470194286 EAN: 9780470194287 sales rank: 173315 Are you baffled by biochemistry? You’re not the first, and you won’t be the last. Here’s the good news — you don’t have to stay baffled! Biochemistry For Dummies shows you the fun and easy way to get a handle on biochemistry, apply the science, raise your grades, and prepare yourself to ace any standardized test. This friendly, unintimidating guide presents an overview of the material covered in a typical college-level biochemistry course and makes biochemistry basics easy to understand. It explains all the topics and practical applications in plain English. From cell ultrastructure and carbohydrates to amino acids, proteins, and supramolecular structure, you’ll identify biochemical structures and reactions, send your grades soaring, and start looking forward to your next class, instead of dreading it. Discover how to:
From water chemistry to protein synthesis Biochemistry For Dummies gives you the vital information, clear explanations, and important insights you need to increase your understanding and improve your performance on any biochemistry test. |
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by: Vinay Kumar MBBS MD FRCPath publisher: Saunders, published: 2009-05-28 ASIN: 1416031219 EAN: 9781416031215 sales rank: 5041 One of the best-selling medical textbooks of all time, Robbins and Cotran Pathologic Basis of Disease is the one book that nearly all medical students purchase, and is also widely used by physicians worldwide. A "who's who" of pathology experts delivers the most dependable, current, and complete coverage of today's essential pathology knowledge. At the same time, masterful editing and a practical organization make mastering every concept remarkably easy. Online access via Student Consult includes self-assessment and review questions, interactive case studies, downloadable images, videos, and a virtual microscope that lets you view slides at different magnifications. The result remains the ideal source for an optimal understanding of pathology.
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publisher: Wiley-Interscience, published: 2004-10-29 ASIN: 0471478784 EAN: 9780471478782 sales rank: 310865 Reviews of the Second Edition "In this book, Andy Baxevanis and Francis Ouellette . . . have undertaken the difficult task of organizing the knowledge in this field in a logical progression and presenting it in a digestible form. And they have done an excellent job. This fine text will make a major impact on biological research and, in turn, on progress in biomedicine. We are all in their debt." --Eric Lander, from the Foreword to the Second Edition "The editors and the chapter authors of this book are to be applauded for providing biologists with lucid and comprehensive descriptions of essential topics in bioinformatics. This book is easy to read, highly informative, and certainly timely. It is most highly recommended for students and for established investigators alike, for anyone who needs to know how to access and use the information derived in and from genomic sequencing projects." --Trends in Genetics "It is an excellent general bioinformatics text and reference, perhaps even the best currently available . . . Congratulations to the authors, editors, and publisher for producing a weighty, authoritative, readable, and attractive book." --Briefings in Bioinformatics "This book, written by the top scientists in the field of bioinformatics, is the perfect choice for every molecular biology laboratory." --The Quarterly Review of Biology This fully revised version of a world-renowned bestseller provides readers with a practical guide covering the full scope of key concepts in bioinformatics, from databases to predictive and comparative algorithms. Using relevant biological examples, the book provides background on and strategies for using many of the most powerful and commonly used computational approaches for biological discovery. This Third Edition reinforces key concepts that have stood the test of time while making the reader aware of new and important developments in this fast-moving field. With a new full-color and enlarged page design, Bioinformatics, Third Edition offers the most readable, up-to-date, and thorough introduction to the field for biologists. This new edition features: * New chapters on genomic databases, predictive methods using RNA sequences, sequence polymorphisms, protein structure prediction, intermolecular interactions, and proteomic approaches for protein identification * Detailed worked examples illustrating the strategic use of the concepts presented in each chapter, along with a collection of expanded,more rigorous problem sets suitable for classroom use * Special topic boxes and appendices highlighting experimental strategies and advanced concepts * Annotated reference lists, comprehensive lists of relevant Web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics Bioinformatics, Third Edition is essential reading for researchers, instructors, and students of all levels in molecular biology and bioinformatics, as well as for investigators involved in genomics, clinical research, proteomics, and computational biology. |
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by: Arthur Lesk publisher: Oxford University Press, USA, published: 2008-06-02 ASIN: 0199208042 EAN: 9780199208043 sales rank: 188517 An Introduction to Bioinformatics introduces students to the immense power of bioinformatics as a set of scientific tools. The book explains how to access the data archives of genomes and proteins, and the kinds of questions these data and tools can answer, such as how to make inferences from data archives and how to make connections among them to derive useful and interesting predictions. Blending factual content with many opportunities for active learning, An Introduction to Bioinformatics offers a truly reader-friendly way to get to grips with this subject, making it the ideal resource for anyone new to the field. Features - Strikes a careful balance between biology and computer science, introducing those aspects of computer science which underpin the subject without demanding detailed prior knowledge. - Contains numerous learning features, including exercises, problems, and WebLems. - Retains the eloquent style and clarity of explanation for which the author is renowned. - An Online Resource Centre includes figures from the book available to download to facilitate lecture preparation, as well as a variety of interactive resources, including web links, 3D structures, and data sets. ew to this Edition - New chapter on biological organization in space and reflects recent advances in genomics, transcriptomics, proteomics, and metabolomics. - New chapter on scientific publications and archives provides a state of the art inventory on sourcing scientific literature. - Expanded coverage of structural bioinformatics. - Enhanced Online Resource Centre, with new guided tours of key websites, and lab assignments to support the in-depth exploration of concepts and themes covered in the book. |