Related books on 'ribosome'
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publisher: Springer, published: 2011-09-28 ASIN: 3709102146 EAN: 9783709102145 sales rank: 2071525 The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come. |
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publisher: Springer, published: 2011-11-17 ASIN: 1617793787 EAN: 9781617793783 sales rank: 2130604 Display technologies have become a very powerful way of generating therapeutic lead molecules and specific reagents for increasing our understanding of biology; however, despite being first described shortly after phage display, the use of ribosome display and related methods have been much less widespread. Since this is in part due to the complexity of the methods, Ribosome Display and Related Technologies: Methods and Protocols seeks to extend their use by collecting expert contributions describing these detailed protocols. The protocols described range from well-established methods that have been used for a decade to generate high affinity antibodies, which are already in the clinic, to methods that are in their early stages of application such as display of peptides incorporating non-canonical amino acids. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Invaluable and easy to use, Ribosome Display and Related Technologies: Methods and Protocols will be of great benefit to those with general molecular biology or protein engineering experience who wish to select peptides or proteins by display, those with phage display experience who would benefit from the application of ribosome display, as well as those with some ribosome display experience who would like to expand the range of applications to which they are applying the technology. |
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publisher: Academic Press, published: 1989-01-11 ASIN: 0121820653 EAN: 9780121820657 sales rank: 1003732 This volume includes a variety of methods involving electron microscopy and other biophysical methods, such as crystallography, neutron scattering, and NMR procedures for the analysis of protein-RNA or RNA-RNA interactions by cross-linking, the use of chemical, enzymatic, and immunological probes, as well as functional and genetic approaches for the study of this nucleoprotein. These methodologies will contribute to the progress toward the elucidation of the structure, function, and regulatory processes that affect this most important complex cellular component, the ribosome. |
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by: Cold Spring Harbor Laboratory publisher: Cold Spring Harbor Laboratory Press, published: 2002-05-01 ASIN: 0879696206 EAN: 9780879696207 sales rank: 3740699 This is the first book to contain the newly published findings on the structure of the ribosome and discuss their meaning for our understanding of how proteins are made and processed inside the cell. With over 60 contributions from the worlds most innovative ribosome biology laboratories, this is the latest volume in the annual series that for over 60 years has provided analysis and interpretation of the most interesting problems in biology. |
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by: Alexander S. Spirin publisher: Springer, published: 2000-02-01 ASIN: 0306461455 EAN: 9780306461453 sales rank: 5678261 Dr. Spirin is a world authority on ribosomes and has published two earlier books in this area in English. This text is for advanced undergraduates and beginning graduate students and will cover the structure, function, and biosynthesis of ribosomes. Ribosomes are important in protein synthesis, which is currently a hot topic in many different areas of research. |
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by: Icon Group International publisher: ICON Group International, Inc., published: 2010-03-10 ASIN: 1114435325 EAN: 9781114435322 Webster's bibliographic and event-based timelines are comprehensive in scope, covering virtually all topics, geographic locations and people. They do so from a linguistic point of view, and in the case of this book, the focus is on "Ribosome," including when used in literature (e.g. all authors that might have Ribosome in their name). As such, this book represents the largest compilation of timeline events associated with Ribosome when it is used in proper noun form. Webster's timelines cover bibliographic citations, patented inventions, as well as non-conventional and alternative meanings which capture ambiguities in usage. These furthermore cover all parts of speech (possessive, institutional usage, geographic usage) and contexts, including pop culture, the arts, social sciences (linguistics, history, geography, economics, sociology, political science), business, computer science, literature, law, medicine, psychology, mathematics, chemistry, physics, biology and other physical sciences. This "data dump" results in a comprehensive set of entries for a bibliographic and/or event-based timeline on the proper name Ribosome, since editorial decisions to include or exclude events is purely a linguistic process. The resulting entries are used under license or with permission, used under "fair use" conditions, used in agreement with the original authors, or are in the public domain. |
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publisher: American Society for Microbiology, published: 1990-10 ASIN: 1555810209 EAN: 9781555810207 sales rank: 4510629 "This book is recommended as a 'hitchhiker's guide to the ribosome' for everyone with an interest in translation, RNA-protein structures, and macromolecular structure-function relationships" Science. |
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by: A. A. Hadjiolov publisher: Springer-Verlag, published: 1984-12 ASIN: 0387817905 EAN: 9780387817903 sales rank: 10751056 |
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publisher: Oxford University Press, USA, published: 1990-08-30 ASIN: 0199631050 EAN: 9780199631056 sales rank: 3679610 The ribosome is a complex and fascinating organelle that occupies a central role in cell metabolism. Although specialist books concerning the ribosome appear frequently, there has been, up to now, a lack of concise, self-contained, introductory information dealing with this organelle at a practical level. This book has been designed to fill that gap with detailed (but not too technical) articles covering a wide range of topics within this vast domain. The initial chapters will enable the reader to construct cell-free protein-synthesizing systems from highly purified components. The subsequent chapters are intended to create an understanding of the methods which are now being used to elucidate structure and function. This fully illustrated volume will be of use to biochemists, geneticists, molecular biologists, and biophysical chemists, as well as graduate students and researchers in these fields. |
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publisher: Academic Press Inc, published: 1979-02 ASIN: 0124106501 EAN: 9780124106505 |