Related books on 'signal-transduction'
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by: Friedrich Marks publisher: Garland Science, published: 2008-11-14 ASIN: 0815342152 EAN: 9780815342151 sales rank: 436713 Cellular Signal Processing is intended for use in signal transduction courses for undergraduate and graduate students. It offers a unifying view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication. The content is guided by three major principles that are central to signal transduction: the protein network, its energy supply, and its evolution. It includes coverage of all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling. It also highlights the clinical aspects of cell signaling in health and disease. |
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by: MobileReference publisher: MobileReference, published: 2006-12-04 ASIN: B004L9LAC8 sales rank: 114240 Boost your grades with Biochemistry study guide, also known as "cheat sheet". FREE Biomolecules chapter and Periodic Table in the trial version. Audience Intended for everyone interested in Biochemistry, particularly undergraduate and graduate life science students. Features Fully illustrated. Complete lists of amino acids, functional groups, chemical classes. IUPAC nomenclature Periodic Table Navigate from Table of Contents or search for the words or phrases Use your down time to prepare for an exam. Always have the guide available for a quick reference. Table of Contents Chapters:I. BiomoleculesII. Chemical PropertiesIII. Structural CompoundsIV. Enzymes V. Membranes And Transport VI. Energy Pathways VII. Signal Transduction VIII. Techniques Appendices:General IndexCommon AtomsHydrocarbons Standard Amino Acids Functional groups Chemical classes IUPAC nomenclature Periodic Table Setup and Navigation About I. Biomolecules Carbohydrates: Monosaccharides | Sugar | Disaccharide | Oligosaccharide | Polysaccharide | Starch | Glycogen | Gluconeogenesis Lipids: Fatty Acids | Fatty Acid Degradation | Fatty Acid Synthesis | Triglyceride | Waxes | Lipoprotein | Phospholipids | Cholesterol Nucleic acids: DNA | DNA replication | Mitochondrial DNA | RNA | mRNA | tRNA | Non-coding RNA | siRNA | RNA Degradation | Codon | Adenin | Cytosine | Guanine | Thymine | Uracil | Oligonucleotides Proteins: Amino acid | Peptide | Primary structure | Secondary structure | Tertiary structure | Protein folding | Protein Degradation II. Chemical Properties Bonds: Covalent | Non-covalent | Ionic bond | Hydrogen bond | Van der Waals attractions | Hydrophobic forces Hydrophilicity: Hydrophilic | Hydrophobic | Polarity pH: pH | Acid | Alkaline | Base Redox: Reduction and oxidation | Citric acid cycle | Hydrolysis III. Structural Compounds In cells: Actin | Intermediate filament | Microtubule | Flagellin | Peptidoglycan | Myelin | Myosin In animals: Chitin | Keratin | Collagen | Silk In plants: Cellulose | Lignin | Cell wall IV. Enzymes Enzymes: Etymology and history | 3D Structure | Thermodynamics | Kinetics | Inhibition | Metabolic pathways and allosteric enzymes | Enzyme-naming conventions Examples: Ubiquitin | Kinase | Dehydrogenase | Proteasome V. Membranes And Transport Structure: Fluid mosaic model | Detailed Structure Membrane Components: Phospholipids | Sphingomyelin | Glycolipid Movement of Molecules: Diffusion | Osmosis | Electrochemical gradient | Membrane permeability Passive transport: Facilitated diffusion | Ion channel Active transport: ATP-Dependent Na/K Pump | V-ATPase | Proton pump | Electron transport | Antiporter | Symporter | Exocytosis | Endocytosis VI. Energy Pathways Cellular respiration: Aerobic respiration | Theoretical yields | Anaerobic respiration | Adenosine triphosphate (ATP) 1. Glycolysis: Preparatory phase | Pay-off phase | Entry of sugars | Control of flux | Energy pay-off | Follow-up | Intermediates for other pathways | High aerobic glycolysis | Alternative nomenclature | Oxidative decarboxylation 2. Krebs cycle/Citric Acid cycle 3. Oxidative Phosphorylation and much more... |
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by: Bastien D. Gomperts publisher: Academic Press, published: 2009-08-19 ASIN: 0123694418 EAN: 9780123694416 sales rank: 713004 Signal Transduction, 2e Bastien D. Gomperts University College, London, United Kingdom Ijsbrand M. Kramer University of Bordeaux, Talence, France Peter E.R. Tatham University College, London, United Kingdom Miranda Gomperts KEY FEATURES: * Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention * In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and adaptive immunity; and intracellular calcium * Extensive conceptual colour artwork to assist with comprehension of key topics * Instrumental margin notes highlight milestones in signalling mechanisms DESCRIPTION: Signal Transduction is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. RELATED TITLES: Latchman: EUKARYOTIC TRANSCRIPTION FACTORS, 3E (1998; ISBN: 0-12-437176-0; $62.95) · In-depth insight into a subject central to cell biology and fundamental to biomedicine, including drug development · Extensive conceptual colour artwork to assist with comprehension of key topics · Special emphasis on the integration of how molecular (domain) structure determines protein function · Comprehensive referencing of both core and historical literature · Guided access and inclusion of Protein Data Bank and Swiss-Prot accession codes and URLs |
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by: MobileReference publisher: MobileReference, published: 2006-12-06 ASIN: B004L9KY0W sales rank: 402539 Boost grades with this illustrated Quick-Study Guide. You will use it from an undergraduate school all the way to medical school. FREE Neurocellular Anatomy chapter in trial version. Audience: Intended for everyone interested in Neurophysiology, particularly undergraduate and graduate life science students, medical students, and nursing students. Features: - Fully illustrated. - Written in clear, concise format. - Difficult concepts are explained in simple terms. Table of Contents I. Neurocellular Anatomy Neuron: Axon | Dendrite | Apical dendrite | Dendritic spine | Afferent nerve | Efferent nerve | Sensory nerve | Motor nerve Axonal Transport and Growth: Axoplasmic transport | Kinesin | Dynein | Myosin | Growth cone | Axon guidance Synapse: Synaptic Vesicles | Exocytosis | Endocytosis | Synaptic plasticity | SNARE | Synaptobrevin | Synapsin | NSF | Excitatory synapse | Inhibitory synapse | Electrical synapse | Gap junction Types of neurons: Pyramidal cell | Betz cell | Purkinje cell | Neuromuscular junction | Muscle spindle | Golgi organ | Motor neuron | Sensory neuron Glial cell: Astrocyte | Oligodendrocyte | Schwann cell | Myelin | Nodes of Ranvier Cytoskeleton: Actin | Intermediate filament | Microtubule II. Membranes And Transport Membrane Structure: Fluid mosaic model | Detailed Structure Membrane Components: Phospholipids | Sphingomyelin | Glycolipid | Glycocalix | Cholesterol Movement of Molecules: Diffusion | Osmosis | Electrochemical gradient Passive transport: Facilitated diffusion | Ion channel Active transport: ATP-Dependent Na/K Pump | Proton pump | Antiporter | Symporter III. Ion Channels Channels: Ion channel | Gap junction Voltage-gated: Potassium channel | Sodium channel | BK channel | Inward-rectifier potassium ion channel | Resting channels | Calcium channel Ligand-gated: NMDA receptor | AMPA receptor | Kainate receptor | Nicotinic acetylcholine receptor | Glycine receptor | GABA receptor Other ion channels: Cyclic nucleotide-gated | Stretch-activated | G-protein-gated | Light-gated | Gap junction IV. Electrical Phenomena Review: Electrical charge | Resistance | Capacitance Resting Membrane Potential: Ionic Basis | Number of ions involved in generating the resting potential | Equilibrium potential | Other values of membrane potential | Implications | Nernst equation | Goldman equation | Depolarization | Hyperpolarization Action Potential: Threshold and initiation | Circuit model | Propagation | Refractory period | Evolutionary purpose | Nodes of Ranvier | Reflex arc Postsynaptic Potential: Excitatory postsynaptic potential | Inhibitory postsynaptic potential | Spatial summation | Temporal summation | Shunting V. Signal Transduction Extracellular Signalling - Neurotransmitters and receptors: Acetylcholine | Degradation by acetylcholinesterase | Ach Receptors ... More Medical e-Books from MobileReference: Anatomy and Physiology, Human Nervous System, Neurophysiology, Neurochemistry, Biochemistry, Biology, Cell Biology, Organic Chemistry, Pharmacology, Medical Abbreviations and Terminology, Acupressure Guide, and more - search keyword MobileReference |
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by: John Hancock publisher: Oxford University Press, USA, published: 2010-03-26 ASIN: 0199232105 EAN: 9780199232109 sales rank: 194260 Signalling within and between cells is an essential part of many biological processes, from the development of the body to the activity of our immune system. Cell Signalling, Third Edition, presents a carefully structured introduction to this intricate subject, introducing those conserved features that underlie many different extra- and intracellular signalling systems. Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms before examining how these components come together to create signalling pathways, which are so crucial to the survival of many living organisms. The text is enhanced by two-color artwork and 3-D protein models. A Companion Website provides resources for students and instructors. New to this edition: * Expanded coverage of the role of cell signalling during development, experimental techniques, and the control of gene expression * New "Literature Links" encourage students to engage with primary literature and to develop critical thinking and reading skills * New four-part structure organizes the subject according to its conceptual basis, the mechanisms of signalling, and their role in natural phenomena |
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by: Gerhard Krauss publisher: Wiley-VCH, published: 2008-04-15 ASIN: 3527313974 EAN: 9783527313976 sales rank: 1005571 This all-new edition of a best-selling text has been thoroughly updated to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity, the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis is made transparent for everyone with a basic knowledge in biochemistry or molecular biology. "Valuable up-to-date information on biochemistry of signal transduction and regulation" (AFS) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research) |
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by: Ari Sitaramayya publisher: Birkhäuser Boston, published: 1998-12-31 ASIN: B000WNBQVW The mechanism of information transfer between cells is the subject of Introduction to Signal Transduction. Until recently various aspects of signaling by hormones were studied (and taught) under the subject of endocrinology, and signaling by neurotransmitters was the subject of neurochemistry. With growing awareness of the many similarities between hormonal and neurotransmitter signalling, recent years have witnessed the emergence of Signal Transduction as an independent discipline covering all aspects of information transfer between cells irrespective of the nature and source of the signals. This book is designed for senior undergraduate/graduate-level students interested in a basic understanding of the major participants in the cellular Signal Transduction pathways. The book covers the major topics in Signal Transduction: receptors, which recognize the signals at the cell surface; G-proteins, which transduce the signals; and adenylate cyclases, guanlate cyclases, and phospholipases, which generate second messengers. Chapters also focus on ion channels, phosphodiesterases, protein kinases, phosphoprotein phosphatases and nitric oxide, which participate in the cellular response to signals; the health consequences of defects in Signal Transduction proteins; and the central role Signal Transduction plays in drug abuse. The book is suitable for an introductory course in Signal Transduction as well as for self-study and review. It is recommended for biology and medical students, as well as for interdisciplinary science majors and pharmaceutical researchers. |
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by: Robert K. Ockner publisher: Springer, published: 2012-03-31 ASIN: 1441934502 EAN: 9781441934505 sales rank: 11097879 This book demonstrates how metabolism and energetics are directly linked to those signal transduction pathways that are essential to survival of the cell, the organism, and the species. Recurring patterns of interaction among metabolism, energetics, and signal transduction are fundamental in diverse aspects of human health and disease. This book explores these phenomena in relation to cell growth and death, cancer, atherosclerosis and Alzheimer disease. Part I of the book explores the origins and theory of integration. Topics covered in Part II include: nutrient and energy metabolism in cell proliferation; fatty acids and growth regulation; mitochondrial function in cell growth and death; metabolic effects of antiproliferative agents; fatty acids and mitochondria, cell growth and injury; metabolism and gene expression. Part III of the book deals with energetics of neuronal activation; utilization of oxidizable substrates in the brain; astrocyte metabolism and astrocyte-neuron interaction; neuronal energy metabolism in the brain; astroctyes as metabolic buffer and mediator of neuronal injury; and metabolic factors in the pathogenesis of Alzheimer Disease. |
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by: John Nelson publisher: Wiley, published: 2008-08-26 ASIN: 0470025506 EAN: 9780470025505 sales rank: 3672181 "This book contains extremely detailed and informative content on structure and function of ligands, receptors, and signalling intermediates plus interactions … the extent of detail and appropriate referencing is impressive." –Microbiology Today, July 2009 "A very well-written book suitable for use as a reference or textbook for an undergraduate subject in cell signalling. For researchers interested in the molecular basis of cell signalling and how aberrant regulation of cell signalling proteins causes diseases, this is an excellent resource of biochemical and structural information." –Australian Biochemist, August 2009 "From basics to details, this is an elegantly written and carefully edited book. The chapters on cell cycle control and oncogenesis are particularly fascinating and valuable to biomedical research. This is the book to have if you are interested in molecular mechanisms of signal transduction. It is a great introduction to the literature that will be welcomed by students and experts alike." –Doody's, January 2009
With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding.
Structure and Function in Cell Signalling is an invaluable resource to students across a range of life science degree programmes including biochemistry, cell and molecular biology, physiology, biomedicine and oncology. This book provides a clear, accessible introduction to this rapidly expanding field. |
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publisher: Academic Press, published: 2011-04-26 ASIN: 0123838622 EAN: 9780123838629 sales rank: 1156313 Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences.
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