Related books on 'stem-cell'

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by: Jonathan Slack
publisher: Oxford University Press, USA, published: 2012-04-01
ASIN: 0199603383
EAN: 9780199603381
sales rank: 81386
Embryonic stem cells have been hot-button topics in recent years, generating intense public interest as well as much confusion and misinformation. In this Very Short Introduction, leading authority Jonathan Slack offers a clear and informative overview of stem cells--what they are, what scientists do with them, what stem cell therapies are available today, and how they might be used in the future. Slack explains the difference between embryonic stem cells, which exist only in laboratory cultures, and tissue-specific stem cells, which exist in our bodies, and he discusses how embryonic stem cells may be used in the future to treat such illnesses as diabetes, Parkinson's disease, heart disease, spinal trauma, and retinal degeneration. But he stresses that, despite important advances, the clinical applications of stem cells are still in their infancy and that most real stem cell therapy today is some form of bone marrow transplantation. Slack concludes by analyzing how medical innovation has occurred in this area in recent years and he draws out some of the lessons for the development of new therapies in the future.

by: Alice Park
publisher: Hudson Street Press, published: 2011-06-09
ASIN: 159463078X
EAN: 9781594630781
sales rank: 192872
A landmark book by the senior science writer at Time magazine introduces us to a medical breakthrough that can save our lives.

Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science that will revolutionize medicine and change the way we think about and treat disease.

Alice Park takes us from stem cell's controversial beginnings to the recent electrifying promise of being able to create the versatile cells without using embryos at all. She shows us how stem cells give researchers an unprecedented ability to study disease while giving patients the promise of replacing diseased cells with healthy new ones. And she profiles the scientists and leaders-many with their own compelling stories-who have fueled the quest and will continue to shape the field in years to come.




by: Lawrence S.B. Goldstein
publisher: For Dummies, published: 2010-02-02
ASIN: 0470259280
EAN: 9780470259283
sales rank: 86659

The first authoritative yet accessible guide to this controversial topic

Stem Cell Research For Dummies offers a balanced, plain-English look at this politically charged topic, cutting away the hype and presenting the facts clearly for you, free from debate. It explains what stem cells are and what they do, the legalities of harvesting them and using them in research, the latest research findings from the U.S. and abroad, and the prospects for medical stem cell therapies in the short and long term.

  • Explains the differences between adult stem cells and embryonic/umbilical cord stem cells
  • Provides both sides of the political debate and the pros and cons of each side's opinions
  • Includes medical success stories using stem cell therapy and its promise for the future

Comprehensive and unbiased, Stem Cell Research For Dummies is the only guide you need to understand this volatile issue.


publisher: Academic Press, published: 2009-07-06
ASIN: 0123747295
EAN: 9780123747297
sales rank: 169399
First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered.

* Contributions by Nobel Laureates and leading international investigators
* Includes two entirely new chapters devoted exclusively to iPS written by the scientists who made the breakthroug
* Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate

by: Christine Mummery
publisher: Academic Press, published: 2011-01-14
ASIN: 0123815355
EAN: 9780123815354
sales rank: 410375

In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues of which everyone presumed were unable to regenerate in adults; these include particularly the heart and the brain. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson, diabetes and spinal cord lesions based on the use of stem cells and entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies.

As is often the case in science, many early claims turned out to be different from those expected. Embryonic stem cell therapies have not moved rapidly into clinical practice. Adult stem cells certainly have given certain degrees of success but not nearly to the extent that advocates would have wished for. Some claims of early successes in adult stem cell therapies have not been sustained in double-blinded, randomized clinical trials. Some claims are now close to routine therapy. Some of the claims not supported by evidence have nevertheless reached private clinical practice so that "stem cell tourism" is beginning to reach exaggerated proportions.

This book provides the reader background information on stem cells in a clear and well-organized manner. It provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. It distinguishes itself from the multiplicity of websites on the subject of stem cells by being scientifically, politically and ethically neutral, explaining pros and cons for stem cells of every sort with the intention of reaching a wide readership ranging from advanced students and patient advocacy groups to clinicians, specialists and early phase medics in training. By providing the background scientific and social information, it provides readers with the information they require to form their own opinions on the use of stem cells on the basis of facts rather than hype.

*  Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy

*  Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice

* Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice


by: Bruce Alberts
publisher: Garland Science, published: 2007-11-16
ASIN: 0815341059
EAN: 9780815341055
sales rank: 6016

For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter).

The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features.

It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as PDF files on the free Media DVD-ROM which accompanies the book.* And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and they will help students review and extend their knowledge derived from reading the textbook. The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint® presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies—animations, videos, and molecular models—all with voice-over narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well.

By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology.

* There is also a reference edition of Molecular Biology of the Cell, Fifth Edition (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format.


by: Joseph H. Antin MD
publisher: Cambridge University Press, published: 2009-03-02
ASIN: 0521699754
EAN: 9780521699754
sales rank: 446682
Over the past 35 years, stem cell and bone marrow transplantation have evolved from experimental therapies to well-established and widely used treatments for a variety of malignant and nonmalignant conditions. This is a practical pocket manual for all members of the stem cell and bone marrow transplant team, based on a popular in-house handbook used at the Dana-Farber Cancer Institute. The manual covers all aspects of the transplantation process, from stem cell processing through management of transplant-related complications. Evaluation and counseling of patients and donors, preventative care, and conditioning regimens are also covered, making this an ideal resource for nurses as well. The text is handily arranged in outline format to maximize the usefulness and convenience of this resource.

publisher: Academic Press, published: 2007-06-15
ASIN: 0123704650
EAN: 9780123704658
sales rank: 584260
Stem cells are self-replicating and undifferentiated, meaning their function is not yet cell, tissue, or organ-specific. Due to the unique nature of these cells, research into their biology and function holds great promise for therapeutic applications through replacement or repair of diseased and damaged cells. This reader-friendly manual provides a practical "hands on" guide to the culture of human embryonic and somatic stem cells. By presenting methods for embryonic and adult lines side-by-side, the authors lay out an elegant and unique path to understanding the science of stem cell practice. The authors begin with a broad-based introduction to the field, and also review legal and regulatory issues and patents. Each experimental strategy is presented with an historical introduction, detailed method, discussion of alternative methods, and common pitfalls. This lab guide for researchers also serves as a textbook for undergraduate and graduate students in laboratory courses.

by: Michael Bellomo
publisher: AMACOM, published: 2006-08-11
ASIN: B003YCQFKU
sales rank: 379210
There has been much recent debate about the merits, dangers, and nature of stem cell research. Some see in it the answer to every debilitating disease known to man, while others see it as a step away from human cloning.

While the battle has raged, research is moving ahead, and California has already passed a measure that will give $3 billion in support to stem cell research. But as politics, religion, and the media weigh in on this complex issue, more and more of the scientific reality of stem cell research is getting lost. In the search for the truth about stem cell science, the author has interviewed the scientists whose cutting-edge research is at the very heart of this hot-button issue. The book explains what they have accomplished so far, what they're currently doing, and what they see on the horizon.

The Stem Cell Divide does not take sides, and the author debunks the distortions and exaggerations that come from every camp. This book does not tell readers what to think, but gives them the facts necessary to form their own opinions about one of the most divisive, complex, and potentially life-changing developments in history.


by: Jeremy W. Dale
publisher: Wiley, published: 2012-02-14
ASIN: 0470683856
EAN: 9780470683859
sales rank: 76684
The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation.
The new edition features:
  • Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics.
  • Clear, two-colour diagrams throughout.
  • A dedicated website including all figures.

Noted for its outstanding balance between clarity of coverage and level of detail, this book provides an excellent introduction to the fast moving world of molecular genetics.

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