Related books on 'dna-methylation'
Return to life science book listNumber of products: 6226
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by: Roger L.P. Adams publisher: Springer, published: 1985-11-22 ASIN: 0387961615 EAN: 9780387961613 sales rank: 8673175 |
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by: H. P. Saluz publisher: Birkhauser, published: 1990-08 ASIN: 0817623698 EAN: 9780817623692 sales rank: 8952327 |
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by: Moshe Szyf publisher: Springer, published: 2010-12-06 ASIN: 1441934162 EAN: 9781441934161 This book provides a comprehensive analysis of implications of DNA methylation on cancer diagnosis and cancer therapy. This unique volume focuses on cancer therapy by thoroughly dissecting the basic principles of DNA methylation in cancer from molecular mechanisms to clinical trials. The chapters are written by leading experts in the field and are designed to provide the reader with the necessary background to evaluate critically the potential of DNA methylation in cancer therapy. Key features of this book include discussions of the following topics: The molecular machinery responsible for DNA methylation and their impact on gene expression and tumorigenesis. The emerging relation between DNA methylation and chromatin modifying proteins. How the relationship between DNA methylation and chromatin modifying proteins might clarify the mechanisms and therapeutic implications of aberrant DNA methylation in cancer. Illustrations of the diagnostic potential of methylation in cancer and novel tools for using methylation profiling of cancers. The therapeutic potential of the DNA methylation machinery and novel attempts to target the DNA methylation enzymes in anticancer therapy. This book will be of interest to a wide audience, including oncologists, researchers and clinicians, and graduate students in the fields of oncology, molecular biology, and cancer therapy, as well as researchers and decision-makers in industry focusing on anticancer drugs and diagnosis. |
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by: Suzanne Somers publisher: Crown Archetype, published: 2012-05-08 ASIN: 0307588548 EAN: 9780307588548 sales rank: 109 Are you ready to rethink and redefine your approach to aging? This powerhouse book tells you how to go from dreading it to making it the greatest passage of your life! Dubbed a health pioneer by the Wall Street Journal and called “crazy smart” by Dr. Mehmet Oz, Suzanne Somers has repeatedly opened up new terrain to health seekers worldwide. And now, with Bombshell, she does it again. Acting like your personal medical detective, she has found the most advanced scientists, doctors, and health professionals and gotten them to share jaw-dropping advances that will stop deterioration and set you on the path to restoration and healthy longevity. By taking advantage of these new bombshell advancements, you can live longer than ever with great quality of life, and experience a different way to age: with great health, strong bones, vitality, a working brain, and sizzling sexuality. All of it is yours for the taking if you are willing to make some simple, effective changes. In Bombshell you will learn about explosive medical secrets utilizing the groundbreaking technologies of today, or the very near future, that will allow us all to truly maintain the fountain of youth, including: • How nanobots, small “robots” the size of blood cells, will be injected into the human bloodstream to clean the blood supply and literally wipe out today’s most feared diseases• How stem cell procedures, using one’s own adult stem cells, can be used to prevent disease and even regrow body parts; including how Suzanne’s breast was reconstructed after cancer with no implant in the first clinical trial of its kind in the United States • How balancing hormones with bioidentical hormone replacement therapy can improve your internal health, well-being, vitality, looks, and sex drive • How the “cure” to cancer might be just around the corner by preventing it at the source with injections of human, cancer-resistant white blood cells • How a supplement to regrow telomeres at a cellular level will restore the human body to a younger internal age and reverse signs of aging such as disease, baldness, wrinkles, and loss of hearing and eyesight. And it’s available now! One after another, she shares the breakthroughs that you can use today to keep you in top shape so you can embrace the near future and all it will have to offer. |
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by: Frank H. Stephenson publisher: Prometheus Books, published: 2007-01-30 ASIN: 159102482X EAN: 9781591024828 sales rank: 647467 In the fall of 2005, leading scientists from the National Cancer Institute announced the beginning of the cancer genome atlas project, a large-scale endeavour to map every gene implicated in cancer and the first step toward development of new therapies for treating this still baffling disease. This spin-off of the human genome project is only the latest exciting research advance in a decades-long quest to fully understand the biochemistry of the human body and thereby gain insights into the secrets of health, disease, and ageing. Biochemist and veteran lab researcher Frank H. Stephenson tells the compelling story of how scientists on many fronts are succeeding in the battle against disease. With a gift for making the complexities of genetics and biochemistry understandable to the average reader, Stephenson offers a fascinating tour of the mechanisms of our body and the therapeutic techniques that are gaining in sophistication and effectiveness every year. From heart disease to AIDS and cancer, he helps you understand how the tools of biotechnology are being used to combat our most common afflictions. Stephenson examines a wide variety of health threats and illnesses: HIV infection, the many forms of cancer, asthma, diabetes, Alzheimer's, obesity, and even erectile dysfunction. Each is discussed in terms of its root cause and treatment in plain, jargon-free language that not only educates but also entertains. This is the ideal primer on the biotechnology revolution for the layperson. Stephenson offers many insights into both the diseases that destroy health and the great promises that biotechnology offers for preserving and prolonging a healthy life. |
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by: Chris R. Calladine publisher: Academic Press, published: 2004-04-13 ASIN: 0121550893 EAN: 9780121550899 sales rank: 1027459 The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth. The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication. Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA. * Describes the basic units of DNA and how these form the double helix, and the various types of DNA double helix * Outlines the methods used to study DNA structure * Contains over 130 illustrations, some in full color, as well as exercises and further readings to stimulate student comprehension |
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publisher: Springer, published: 2011-01-11 ASIN: 9048169178 EAN: 9789048169177 sales rank: 3527712 This book provides a broad and rich outline of the epigenetic mechanisms involved in cancer progression and the generation of metastasis. It describes the tumor suppressor genes undergoing transcriptional silencing by CpG island promoter hypermethylation in the different tumor types of the human anatomy and their association with tumoral behaviour. It also provides a comprehensive insightful look at the molecular players involved in DNA methylation, histone modification and chromatin remodelling complexes causing epigenetic lesions linked to the metastasic phenotypes. Finally, it explains how epigenetic lesions associated with cancer spreading can be targeted using new and potent chemotherapy drugs. The book is a state-of-the-art reference to all scientific researchers and clinicians interested in the understanding of the biological processes leading to tumor dissemination and to those that are keen to translate this knowledge to a better management of cancer patients. Each contributor is a specialist in their epigenetic area and their joint effort has created a unique view of the DNA methylation, histone and chromatin changes that define cancer metastasis. |
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by: Sorin Drghici publisher: Chapman and Hall/CRC, published: 2011-12-06 ASIN: 1439809755 EAN: 9781439809754 sales rank: 84413 Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that teaches students the basics of R and microarray technology as well as how to choose and apply the proper data analysis tool to specific problems. New to the Second Edition With all the necessary prerequisites included, this best-selling book guides students from very basic notions to advanced analysis techniques in R and Bioconductor. The first half of the text presents an overview of microarrays and the statistical elements that form the building blocks of any data analysis. The second half introduces the techniques most commonly used in the analysis of microarray data. |
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publisher: CRC Press, published: 2009-05-07 ASIN: 1420063545 EAN: 9781420063547 sales rank: 265787 Explores the Newly Discovered Link Between Nutrition and Epigenetics Current research suggests that nutrients are more than just food components and that certain nutrients can impact the expression of genes that lead to the development of chronic diseases. With contributions from experts in both fields, Nutrients and Epigenetics examines the epigenetic phenomena and the fascinating implications of diet on this largely uncharted field. Generously laden with tables and illustrations, many in color, this book addresses how nutrients alter physiologic and pathologic processes in the human body through epigenetic changes without affecting the DNA sequence. It also explains the detailed molecular structures of epigenetic phenomena and closely examines the current knowledge surrounding the biology of aging and embryonic growth regulation. Assesses the Likelihood of Clinical Applicability In one single compendium, this resource delineates the nutritional factors that further much-studied aberrant epigenetic patterns, such as DNA methylation, histone modifications, and chromatin remodeling. The book spotlights the influence of nutrition on epigenetic gene regulation, opening the way for counteracting future disease processes associated with epigenetic phenomena—a step that could potentially change the face of disease prevention and development. |
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by: Dr. Peter J. D'Adamo publisher: Three Rivers Press, published: 2009-12-29 ASIN: 0767925254 EAN: 9780767925259 sales rank: 22108 “D'Adamo's engaging writing style, enthusiasm for his subject, and personalized advice will appeal to those who enjoy taking a hands-on approach to their health and exploring new theories.” –Publishers Weekly With over five million copies sold worldwide of Eat Right 4 Your Type and additional books in the Blood Type Diet series, Dr. Peter J. D’Adamo pioneered a new, revolutionary approach to dieting–one linked to a person’s blood type. In Change Your Genetic Destiny, he takes his groundbreaking research to the next level by identifying six unique genetic types. Whether you are a Hunter, Gatherer, Teacher, Explorer, Warrior, or Nomad, Dr. D’Adamo offers a customized program that complements your genetic makeup to maximize health and weight loss, as well as prevent or even reverse disease. In simple, concise prose, Dr. D’Adamo explains how a host of environmental factors, including diet and lifestyle, dictate how and when your genes express themselves. He goes on to demonstrate precisely how, with the right tools, you can alter your genetic destiny by turning on the good genes and silencing the bad ones. Your health risks, weight, and life span can all be improved by following the GenoType Diet that’s right for you. Using family history and blood type, as well as simple diagnostic tools like fingerprint analysis, leg length measurements, and dental characteristics, Dr. D’Adamo shows you how to map out your genetic identity and discover which of the six GenoType plans you should follow. Without expensive tests or a visit to the doctor, Change Your Genetic Destiny reveals previously hidden genetic strengths and weaknesses and provides a precise diet and lifestyle plan for every individual. Based on the latest and most cutting-edge research, this is a twenty-first-century plan for wellness and weight loss from a renowned healthcare pioneer. |