Related books on 'laboratory-mice'
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by: Lee M. Silver publisher: Oxford University Press, USA, published: 1995-04-13 ASIN: 0195075544 EAN: 9780195075540 sales rank: 442631 Mouse Genetics offers for the first time in a single comprehensive volume a practical guide to mouse breeding and genetics. Nearly all human genes are present in the mouse genome, making it an ideal organism for genetic analyses of both normal and abnormal aspects of human biology. Written as a convenient reference, this book provides a complete description of the laboratory mouse, the tools used in analysis, and procedures for carrying out genetic studies, along with background material and statistical information for use in ongoing data analysis. It thus serves two purposes, first to provide students with an introduction to the mouse as a model system for genetic analysis, and to give practicing scientists a detailed guide for performing breeding studies and interpreting experimental results. All topics are developed completely, with full explanations of critical concepts in genetics and molecular biology. As investigators around the world are rediscovering both the heuristic and practical value of the mouse genome, the demand for a succinct introduction to the subject has never been greater. Mouse Genetics is intended to meet the needs of this wide audience. |
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publisher: Academic Press, published: 2006-12-14 ASIN: 0123694566 EAN: 9780123694560 sales rank: 2162949 Diseases, the second volume in the four volume set, The Mouse in Biomedical Research, departs from the first edition, by discussing specific disease causing microorganisms, rather than the format used in the first edition which discussed infectious diseases affecting specific organs and tissues. As such, the volume consists of 26 chapters subdivided into RNA viruses and DNA viruses, as well as bacterial, mycotic, and parasitic infections. These chapters not only provide updates on pathogenesis, epidemiology and prevention of previously recognized murine pathogens, but also include information on newly recognized disease-causing organisms: mouse parvovirus, cilia associated respiratory bacilli and Helicobacter spp. A separate category, consisting of 3 chapters, discusses zoonoses, tumor pathology of genetically engineered mice, and spontaneous diseases in commonly used mouse strains. |
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publisher: Academic Press, published: 2006-12-19 ASIN: 0123694582 EAN: 9780123694584 sales rank: 2227284 Immunology, the third volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is known about the immune system in mice than any other species except man. In large part this is due to the power of genetic engineering to delineate molecular mechanisms. In this volume we present an Overview to mouse immunology, including both the innate and adaptive immune systems, followed by 15 chapters, each dealing with a specific area of immunology in the mouse. These chapters illustrate the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells. |
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publisher: Academic Press, published: 2006-12-18 ASIN: 0123694558 EAN: 9780123694553 sales rank: 2231248 History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research. |
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by: Douglas Wahlsten publisher: Academic Press, published: 2010-11-05 ASIN: 012375674X EAN: 9780123756749 sales rank: 629255 This book presents the essentials of behavioral test methodology needed for effective study planning and high quality behavioral data collection on laboratory mice. The broad scope of behavioral testing in relation to the neurosciences is discussed, as are the fine details of various test situations. Mistakes made in past research are scrutinized and lessons are drawn about how to avoid them in future work. Diverse factors that can influence the results of behavioral experiments are discussed, ranging from the specific parameters employed in a test to the laboratory environment outside the test situation itself. Throughout the book, emphasis is placed on special issues that arise when testing genetically different mice, including inbred strains and mice with targeted mutations. This knowledge will assist an investigator who lacks formal training in behavioral psychology to build a behavioral testing lab and insure that its output meets current standards of good practice in behavioral neuroscience research. The book will be a convenient manual of procedures for daily use in studies of mouse behavior. It will be of interest even to experienced behavioural researchers, but of particular value to scientists just beginning work with mice, including undergraduate and graduate students as well as postdoctoral investigators who want to collect phenotypic data with knockout and other genetically defined mice. Constructed from materials used in a long running course on Advanced Animal Behavior at University of North Carolina-Greensboro, the book is an ideal text for a course on behavioral testing. * A guide to running a behavioral testing lab, including the many aspects of mouse research beyond the confines of the specific test. * Diagrams and photographs are shown for many kinds of apparatus and test situations with sufficient details such as dimensions to enable building of replicas * Provides step-by-step instructions on planning and executing behavioral experiments in order to run them successfully * A companion website will provide: access to statistical utilities in Excel and test protocols; examples of real documents used for published studies; video clips of the mice behaviors resulting from various tests |
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by: John J. Bogdanske publisher: CRC Press, published: 2010-11-19 ASIN: 1439850445 EAN: 9781439850442 sales rank: 235572 This combination manual and DVD provides much-needed training on the proper handling of rats used in biomedical research. The DVD includes narrated video clips that demonstrate and describe each procedural technique. The manual contains handouts with color illustrations and descriptive text for each technique, including the purpose and application of the procedure, recommended skills, and necessary supplies. It can be used as a training resource and refresher for lab animal veterinarians, veterinary technicians, animal care staff, trainers, and research investigators and staff who work with rats. |
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by: Virginia Papaioannou publisher: Cold Spring Harbor Laboratory Press, published: 2004-11-01 ASIN: 0879696400 EAN: 9780879696405 sales rank: 438758 The generation of mutant mice raises many questions about the best means of phenotypic analysis, breeding, and maintenance. The answers are now available from two experts with a wealth of detailed knowledge never previously assembled in one volume. Informal and highly practical, this handbook provides step by step methods for troubleshooting experiments, from the basics of gene targeting through the analysis of postnatal effects. |
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by: Roscoe B Jackson Memorial Laboratory publisher: Dover Publications, published: 1975-01 ASIN: 0486631850 EAN: 9780486631851 sales rank: 3296531 |
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by: Ada Graham publisher: Atheneum, published: 1981-12 ASIN: 0684171503 EAN: 9780684171500 sales rank: 2329838 Describes the work of scientists at Jackson Laboratory, where mice are bred for laboratories and medical institutions all over the world and studied in connection with research in genetics and hereditary disease. |
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publisher: CRC Press, published: 1999-07-23 ASIN: 0849319056 EAN: 9780849319051 sales rank: 2126220 Experts from The Jackson Laboratory and around the world provide practical advice on everything from how to establish a colony to where to go for specific mutations. Systematic Approach to Evaluation of Mouse Mutations includes information on medical photography, grafting procedures, how to map the genes and evaluate the special biological characteristics of the mice. |