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publisher: Springer, published: 2010-12-01
ASIN: 1441938079
EAN: 9781441938077
sales rank: 3909196
The function of the heart is highly dependent on oxidative energy that is generated in mitochondria. Defects in mitochondrial structure and function can be found in association with cardiovascular diseases. Mitochondria and the Heart discusses the role that mitochondria plays in cardiovascular disease, including biogenesis and function of cardiac mitochondria during normal growth, development and aging. In addition, nonbioenergetic, biogenesis and degradation pathways are explored. Understanding these pathways and the effects that mitochondrial defects have in cardiac pathology is extremely important in establishing the diagnosis and treatment of mitochondrial-based cardiac diseases.
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publisher: Springer, published: 2010-12-01
ASIN: 0387897801
EAN: 9780387897806
sales rank: 2858460
Mitochondria are the product of a long evolutionary history. It is now a well established fact that mitochondria did evolve from free living bacteria being the common ancestor of both, eukaryotic mitochondria and α-proteobacteria. Advances in genome sequencing, the establishment of in organello and in vitro assays to name only a few, contributed significantly to advances in plant mitochondrial research. Second generation sequencing and the ability to directly sequence and analyse the whole plant transcriptome certainly will help to develop the research on plant mitochondria to another level in the future. In this book the current knowledge about plant mitochondria is presented in a series of detailed chapters, which have been organized in five main sections: (i) dynamics, genes and genomes; (ii) transcription and RNA processing; (iii) translation and import; (iv) biochemistry, regulation and function; and (v) mitochondrial dysfunction and repair. These sections consist of two to five chapters, each written by well-known specialists in the field. This book thus provides a comprehensive inside in the field of plant mitochondria for the specialist. The addition of a glossary and text boxes to each chapter provides easy access for readers from other subjects and hopefully will attract young scientist to the fascinating and exiting field of plant mitochondria.
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publisher: Springer, published: 2005-02-24
ASIN: 1402027133
EAN: 9781402027130
sales rank: 3692095
Plant organelles have intrigued biologists since the discovery of their endosymbiontic origin and maternal inheritance. The first application of organelle biotechnology was the role of cytoplasmic male sterility in hybrid seed production and "Green Revolution". In modern times, plant organelles are again leading the way for the creation of genetically modified crops. On a global scale, 75% of GM crops are engineered for herbicide resistance and most of these herbicides target pathways that reside within plastids. Several thousand proteins are imported into chloroplasts that participate in biosynthesis of fatty acids, amino acids, pigments, nucleotides and numerous metabolic pathways including photosynthesis. Thus, from green revolution to golden rice, plant organelles have played a critical role in revolutionizing agriculture. This book details not only basic concepts and current understanding of plant organelle genetics and molecular biology but also focuses on the synergy between basic biology and biotechnology. Forty four authors from nine countries have contributed twenty four chapters containing many figures and tables. Section 1 on organelle genomes and proteomes discusses molecular features of plastid and mitochondrial genomes, evolutinary origins, somatic and sexual inheritance, proteomics, bioinformatics and functional genomics. Section 2 on organelle gene expression and signalling discusses transcription, translation, RNA processing/editing, introns and splicing, protein synthesis, proteolysis, import of proteins into chloroplast and mitochondria and their regulation. Section 3 on organelle biotechnology discusses chloroplast and nuclear genetic engineering for biotic/abiotic stress tolerance, improved fatty acid/amino acid biosynthesis, biopharmaceuticals, biopolymers and biomaterials, cytoplasmic male sterility for hybrid seed production, plant improvement and restoration of fertility. This book is designed to serve as a comprehensive volume and reference guide for teachers, advanced undergraduates and graduate students and researchers in plant molecular biology and biotechnology.
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publisher: Springer, published: 2001-05-31
ASIN: 0306464330
EAN: 9780306464331
sales rank: 4334953
Mitochondria are organelles in each cell outside the nucleus and are the energy source of all cells. As such, they are crucial to the healthy functioning of cells. Recent research has shown that mitochondrial dysfunction underlies a broad spectrum of disease, from maternally inherited genetic disorders to metabolism defects, aging, stroke, and neurodegenerative diseases such as Parkinson's, Alzheimer's, and Lou Gehrig's disease. This book brings together top researchers whose work in examining the pathophysiologic processes will lead to new strategies for prevention and treatment.
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publisher: Academic Press, published: 1986-05-12
ASIN: 0121820254
EAN: 9780121820251
sales rank: 3789376
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.
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publisher: Academic Press Inc, published: 1970-03
ASIN: 0122979508
EAN: 9780122979507
sales rank: 4700706
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publisher: Wiley-Blackwell, published: 2007-05-08
ASIN: 1405149396
EAN: 9781405149396
sales rank: 4442184
Mitochondria are critical organelles in the metabolic regulation of almost all eukaryotic organisms. Knowledge of their biochemistry and molecular biology in plants has been fuelled over recent years by the rapid progress made in genome sequencing and the ability to manipulate gene expression.
Plant Mitochondria contains chapters written by many of the world’s leading researchers in this area, bringing together and reviewing for the first time many recent advances. Contents include coverage of mitochondrial dynamics, mitochondrial genome instability, expression of the plant mitochondrial genome, import of nuclear-encoded mitochondrial proteins, mitochondrial respiratory complex biogenesis, supramolecular structure of the OXPHOS system, mitochondrial electron transport and oxidative stress, mitochondrial metabolism, cytoplasmic male sterilities and mitochondrial gene mutations, and the mitochondrion in plant programmed cell death.
Plant Mitochondria is an extremely important and timely addition to Blackwell Publishing’s Annual Plant Reviews series. David Logan, well known and respected internationally for his work in this area, has brought together a truly valuable volume of great use and interest to plant scientists, cell and molecular biologists, and biochemists. Libraries in all universities and research establishments where biological sciences are studied and taught should have copies of this important book on their shelves.
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publisher: Academic Press, published: 1983-09-11
ASIN: 0121819973
EAN: 9780121819972
sales rank: 6188605
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.
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publisher: Academic Press, published: 1986-05-12
ASIN: 0121820262
EAN: 9780121820268
sales rank: 5533405
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.
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publisher: Academic Press Inc, published: 1970-01
ASIN: 0122412508
EAN: 9780122412509
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