mutation-analysis mutation-detection books

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Mutation Testing for the New Century (Advances in Database Systems) (v. 24)

publisher: Springer, published: 2001-06-30
ASIN: 0792373235
EAN: 9780792373230
sales rank: 5826766
Extensive research and development has produce mutation tools for languages such as Fortran, Ada, C, and IDL; empirical evaluations comparing mutation with other test adequacy criteria; empirical evidence and theoretical justification for the coupling effect; and techniques for speeding up mutation testing using various types of high performance architectures. Mutation has received the attention of software developers and testers in such diverse areas as network protocols and nuclear simulation. Mutation Testing for the New Century brings together cutting edge research results in mutation testing from a wide range of researchers. This book provides answers to key questions related to mutation and raises questions yet to be answered. It is an excellent resource for researchers, practitioners, and students of software engineering.

Microfluidic Technologies for Miniaturized Analysis Systems (MEMS Reference Shelf)

publisher: Springer, published: 2007-11-07
ASIN: 0387285970
EAN: 9780387285979
sales rank: 3150892
This book addresses Lab-on-a-Chip devices. It focuses on microfluidic technologies that have emerged in the past decade. Coverage presents a comprehensive listing of the most promising microfluidic technologies in the Lab-on-a-Chip field. It also details technologies that can be viewed as toolboxes needed to set up complex Lab-on-a-Chip systems.

The Handbook of Plant Mutation Screening (Molecular Plant Biology)

publisher: Wiley-VCH, published: 2010-03-30
ASIN: 3527326049
EAN: 9783527326044
sales rank: 2727062
Induced mutagenesis is a common and promising method for screening for new crops with improved properties. This title introduces the different methods and then focuses on the screening, detection and analysis of the novel mutations. Written by a global team of authors the book is an indispensable tool for all scientists working on crop breeding in industry and academia.

Mutation: The History of an Idea from Darwin to Genomics

by: Elof Axel Carlson
publisher: Cold Spring Harbor Laboratory Pr, published: 2011-06-03
ASIN: 1936113309
EAN: 9781936113309
sales rank: 560240
Today, most scientists regard the term "mutation" as a description of a change in an individual gene, and more precisely as some minute alteration of the DNA of that gene, especially a nucleotide substitution. But the idea of mutation has changed considerably from the pre-Mendelian concepts of Darwin's generation, who viewed "fluctuating variations" as the raw material on which evolution acted, to today's up-to-the-minute genomic context of mutation. History of Mutation: From Darwinian Fluctuations to Comparative Genomics explores six generations of mutation research, providing the background-the people and the ideas---for this biological journey. After exploring Darwin's and Francis Galton's concepts of mutation, Carlson shows how the 1900 rediscovery of Gregor Mendel's experiments let to a discontinuous model of evolution by mutation and how cytological investigations led to the chromosome theory of heredity of classical genetics in which there was random mutation in genes. Carlson details how Mendelian and biometric approaches to heredity and evolution were closely tied and how induction of mutations by radiation and chemical mutagens led to biochemical investigations of gene action, shifting attention to the chemistry of the gene. The interpretation of the gene as DNA and the deciphering of the genetic code then gave rise to molecular interpretations of mutation, views that also impacted evolutionary biology, population genetics, commercial development of plants and animals, and human genetics. This book shows how generational definitions or assessments of mutation have responded to the technologies added to science and the experiments that abounded with the inquiries of each successive generation. These observations are combined with an exploration of how the nonscientific public has shifted its understanding and concern about mutations over the past 150 or more years. Carlson's historical approach in this book-examining the evolution of a concept-reveals the way science works, incrementally by small steps of additions and replacements rather than by dramatic, and rare, paradigm shifts.

Principles of Genome Analysis and Genomics

by: Sandy B. Primrose
publisher: Wiley-Blackwell, published: 2003-01-06
ASIN: 1405101202
EAN: 9781405101202
sales rank: 1685603
With the first draft of the human genome project in the public domain and full analyses of model genomes now available, the subject matter of 'Principles of Genome Analysis and Genomics' is even 'hotter' now than when the first two editions were published in 1995 and 1998. In the new edition of this very practical guide to the different techniques and theory behind genomes and genome analysis, Sandy Primrose and new author Richard Twyman provide a fresh look at this topic. In the light of recent exciting advancements in the field, the authors have completely revised and rewritten many parts of the new edition with the addition of five new chapters. Aimed at upper level students, it is essential that in this extremely fast moving topic area the text is up to date and relevant.

Completely revised new edition of an established textbook.
Features new chapters and examples from exciting new research in genomics, including the human genome project.
Excellent new co-author in Richard Twyman, also co-author of the new edition of hugely popular Principles of Gene Manipulation.
Accompanying web-page to help students deal with this difficult topic at www.blackwellpublishing.com/primrose

Polymorphism Detection & Analysis Techniques

publisher: Eaton Pub Co, published: 2000-12-15
ASIN: 1881299473
EAN: 9781881299479
sales rank: 9739823
(BioTechniques Books) Amersham Pharmacia Biotech, Piscataway, NJ. A collection of 47 key papers taken from BioTechniques journal, providing a complete overview of the science and applications of polymorphism. Includes an array of methods for detecting and analyzing mutations in nucleic acids. Primarily for molecular biologists interested in mutation science. Softcover.

High Performance Liquid Chromatography in Phytochemical Analysis (Chromatographic Science Series)

publisher: CRC Press, published: 2010-11-08
ASIN: 142009260X
EAN: 9781420092608
sales rank: 758379

The powerful, efficient technique of high performance liquid chromatography (HPLC) is essential to the standardization of plant-based drugs, identification of plant material, and creation of new herbal medicines. Filling the void in this critical area, High Performance Liquid Chromatography in Phytochemical Analysis is the first book to give a complete description of the techniques, materials, and instrumentation of column HPLC and its application to essentially all primary and secondary plant metabolites. Hailing from around the world and with vast expertise in HPLC phytochemical analysis, the contributors present a global, authoritative view of the field.

The book looks at the role of HPLC in the analysis of herbal drugs, quality control of plant products in dietary supplements, and chemosystematics. It also covers the phytochemistry, pharmacology, and biological role of plant metabolites as well as various modes and techniques of HPLC analysis. The book then focuses on HPLC separation, identification, and quantification of particular classes of compounds in a variety of sample types, including plants, plant extracts, and plant-derived products.

Along with its companion volume Thin Layer Chromatography in Phytochemistry, this comprehensive book presents the most important analytical approaches used in phytochemical analysis. It will help in solving problems connected with practical separations and the analyses of plant extract fractions of active metabolites.

Introduction to Statistics and Data Analysis (Available Titles Aplia)

by: Roxy Peck
publisher: Brooks/Cole, published: 2011-01-01
ASIN: 0840054904
EAN: 9780840054906
sales rank: 55095
INTRODUCTION TO STATISTICS AND DATA ANALYSIS, 4th Edition, introduces you to the study of statistics and data analysis by using real data and attention-grabbing examples. The authors guide you through an intuition-based learning process that stresses interpretation and communication of statistical information. Simple notation--including the frequent substitution of words for symbols--helps you grasp concepts and cement your comprehension. You'll also find coverage of the graphing calculator as a problem-solving tool, plus hands-on activities in each chapter that allow you to practice statistics firsthand.

An Introduction to Statistical Methods and Data Analysis

by: R. Lyman Ott
publisher: Duxbury Press, published: 2008-12-30
ASIN: 0495017582
EAN: 9780495017585
sales rank: 24895
Ott and Longnecker's AN INTRODUCTION TO STATISTICAL METHODS AND DATA ANALYSIS, Sixth Edition, provides a broad overview of statistical methods for advanced undergraduate and graduate students from a variety of disciplines who have little or no prior course work in statistics. The authors teach students to solve problems encountered in research projects, to make decisions based on data in general settings both within and beyond the university setting, and to become critical readers of statistical analyses in research papers and in news reports. The first eleven chapters present material typically covered in an introductory statistics course, as well as case studies and examples that are often encountered in undergraduate capstone courses. The remaining chapters cover regression modeling and design of experiments.

PCR Mutation Detection Protocols (Methods in Molecular Biology)

publisher: Humana Press, published: 2010-11-10
ASIN: 1617371009
EAN: 9781617371004
1Bimal D. Theophilus and Ralph Rapley provide biological and clinical investigators with a comprehensive collection of new, recent, and updated PCR-based screening methods suitable for detecting the presence of both known and novel mutations. The methods cover point mutations (e.g., ASO-PCR, SSCP, DGGE, chemical cleavage), deletions (multiplex PCR, FISH, blotting), non-sense mutations (PTT), and more. The new and exciting techniques of DNA array analysis, along with such recently developed experimental methods as conformation-sensitive gel electrophoresis, are also included. Each chapter explains the basic theory behind the technique and provides valuable notes essential for its successful execution.

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	Mutation Testing for the New Century (Advances in Database Systems) (v. 24) publisher: Springer, published: 2001-06-30 ASIN: 0792373235 EAN: 9780792373230 sales rank: 5826766 Extensive research and development has produce mutation tools for languages such as Fortran, Ada, C, and IDL; empirical evaluations comparing mutation with other test adequacy criteria; empirical evidence and theoretical justification for the coupling effect; and techniques for speeding up mutation testing using various types of high performance architectures. Mutation has received the attention of software developers and testers in such diverse areas as network protocols and nuclear simulation. Mutation Testing for the New Century brings together cutting edge research results in mutation testing from a wide range of researchers. This book provides answers to key questions related to mutation and raises questions yet to be answered. It is an excellent resource for researchers, practitioners, and students of software engineering.
	Microfluidic Technologies for Miniaturized Analysis Systems (MEMS Reference Shelf) publisher: Springer, published: 2007-11-07 ASIN: 0387285970 EAN: 9780387285979 sales rank: 3150892 This book addresses Lab-on-a-Chip devices. It focuses on microfluidic technologies that have emerged in the past decade. Coverage presents a comprehensive listing of the most promising microfluidic technologies in the Lab-on-a-Chip field. It also details technologies that can be viewed as toolboxes needed to set up complex Lab-on-a-Chip systems.
	The Handbook of Plant Mutation Screening (Molecular Plant Biology) publisher: Wiley-VCH, published: 2010-03-30 ASIN: 3527326049 EAN: 9783527326044 sales rank: 2727062 Induced mutagenesis is a common and promising method for screening for new crops with improved properties. This title introduces the different methods and then focuses on the screening, detection and analysis of the novel mutations. Written by a global team of authors the book is an indispensable tool for all scientists working on crop breeding in industry and academia.
	Mutation: The History of an Idea from Darwin to Genomics by: Elof Axel Carlson publisher: Cold Spring Harbor Laboratory Pr, published: 2011-06-03 ASIN: 1936113309 EAN: 9781936113309 sales rank: 560240 Today, most scientists regard the term "mutation" as a description of a change in an individual gene, and more precisely as some minute alteration of the DNA of that gene, especially a nucleotide substitution. But the idea of mutation has changed considerably from the pre-Mendelian concepts of Darwin's generation, who viewed "fluctuating variations" as the raw material on which evolution acted, to today's up-to-the-minute genomic context of mutation. History of Mutation: From Darwinian Fluctuations to Comparative Genomics explores six generations of mutation research, providing the background-the people and the ideas---for this biological journey. After exploring Darwin's and Francis Galton's concepts of mutation, Carlson shows how the 1900 rediscovery of Gregor Mendel's experiments let to a discontinuous model of evolution by mutation and how cytological investigations led to the chromosome theory of heredity of classical genetics in which there was random mutation in genes. Carlson details how Mendelian and biometric approaches to heredity and evolution were closely tied and how induction of mutations by radiation and chemical mutagens led to biochemical investigations of gene action, shifting attention to the chemistry of the gene. The interpretation of the gene as DNA and the deciphering of the genetic code then gave rise to molecular interpretations of mutation, views that also impacted evolutionary biology, population genetics, commercial development of plants and animals, and human genetics. This book shows how generational definitions or assessments of mutation have responded to the technologies added to science and the experiments that abounded with the inquiries of each successive generation. These observations are combined with an exploration of how the nonscientific public has shifted its understanding and concern about mutations over the past 150 or more years. Carlson's historical approach in this book-examining the evolution of a concept-reveals the way science works, incrementally by small steps of additions and replacements rather than by dramatic, and rare, paradigm shifts.
	Principles of Genome Analysis and Genomics by: Sandy B. Primrose publisher: Wiley-Blackwell, published: 2003-01-06 ASIN: 1405101202 EAN: 9781405101202 sales rank: 1685603 With the first draft of the human genome project in the public domain and full analyses of model genomes now available, the subject matter of 'Principles of Genome Analysis and Genomics' is even 'hotter' now than when the first two editions were published in 1995 and 1998. In the new edition of this very practical guide to the different techniques and theory behind genomes and genome analysis, Sandy Primrose and new author Richard Twyman provide a fresh look at this topic. In the light of recent exciting advancements in the field, the authors have completely revised and rewritten many parts of the new edition with the addition of five new chapters. Aimed at upper level students, it is essential that in this extremely fast moving topic area the text is up to date and relevant. Completely revised new edition of an established textbook. Features new chapters and examples from exciting new research in genomics, including the human genome project. Excellent new co-author in Richard Twyman, also co-author of the new edition of hugely popular Principles of Gene Manipulation. Accompanying web-page to help students deal with this difficult topic at www.blackwellpublishing.com/primrose
	Polymorphism Detection & Analysis Techniques publisher: Eaton Pub Co, published: 2000-12-15 ASIN: 1881299473 EAN: 9781881299479 sales rank: 9739823 (BioTechniques Books) Amersham Pharmacia Biotech, Piscataway, NJ. A collection of 47 key papers taken from BioTechniques journal, providing a complete overview of the science and applications of polymorphism. Includes an array of methods for detecting and analyzing mutations in nucleic acids. Primarily for molecular biologists interested in mutation science. Softcover.
	High Performance Liquid Chromatography in Phytochemical Analysis (Chromatographic Science Series) publisher: CRC Press, published: 2010-11-08 ASIN: 142009260X EAN: 9781420092608 sales rank: 758379 The powerful, efficient technique of high performance liquid chromatography (HPLC) is essential to the standardization of plant-based drugs, identification of plant material, and creation of new herbal medicines. Filling the void in this critical area, High Performance Liquid Chromatography in Phytochemical Analysis is the first book to give a complete description of the techniques, materials, and instrumentation of column HPLC and its application to essentially all primary and secondary plant metabolites. Hailing from around the world and with vast expertise in HPLC phytochemical analysis, the contributors present a global, authoritative view of the field. The book looks at the role of HPLC in the analysis of herbal drugs, quality control of plant products in dietary supplements, and chemosystematics. It also covers the phytochemistry, pharmacology, and biological role of plant metabolites as well as various modes and techniques of HPLC analysis. The book then focuses on HPLC separation, identification, and quantification of particular classes of compounds in a variety of sample types, including plants, plant extracts, and plant-derived products. Along with its companion volume Thin Layer Chromatography in Phytochemistry, this comprehensive book presents the most important analytical approaches used in phytochemical analysis. It will help in solving problems connected with practical separations and the analyses of plant extract fractions of active metabolites.
	Introduction to Statistics and Data Analysis (Available Titles Aplia) by: Roxy Peck publisher: Brooks/Cole, published: 2011-01-01 ASIN: 0840054904 EAN: 9780840054906 sales rank: 55095 INTRODUCTION TO STATISTICS AND DATA ANALYSIS, 4th Edition, introduces you to the study of statistics and data analysis by using real data and attention-grabbing examples. The authors guide you through an intuition-based learning process that stresses interpretation and communication of statistical information. Simple notation--including the frequent substitution of words for symbols--helps you grasp concepts and cement your comprehension. You'll also find coverage of the graphing calculator as a problem-solving tool, plus hands-on activities in each chapter that allow you to practice statistics firsthand.
	An Introduction to Statistical Methods and Data Analysis by: R. Lyman Ott publisher: Duxbury Press, published: 2008-12-30 ASIN: 0495017582 EAN: 9780495017585 sales rank: 24895 Ott and Longnecker's AN INTRODUCTION TO STATISTICAL METHODS AND DATA ANALYSIS, Sixth Edition, provides a broad overview of statistical methods for advanced undergraduate and graduate students from a variety of disciplines who have little or no prior course work in statistics. The authors teach students to solve problems encountered in research projects, to make decisions based on data in general settings both within and beyond the university setting, and to become critical readers of statistical analyses in research papers and in news reports. The first eleven chapters present material typically covered in an introductory statistics course, as well as case studies and examples that are often encountered in undergraduate capstone courses. The remaining chapters cover regression modeling and design of experiments.
	PCR Mutation Detection Protocols (Methods in Molecular Biology) publisher: Humana Press, published: 2010-11-10 ASIN: 1617371009 EAN: 9781617371004 1Bimal D. Theophilus and Ralph Rapley provide biological and clinical investigators with a comprehensive collection of new, recent, and updated PCR-based screening methods suitable for detecting the presence of both known and novel mutations. The methods cover point mutations (e.g., ASO-PCR, SSCP, DGGE, chemical cleavage), deletions (multiplex PCR, FISH, blotting), non-sense mutations (PTT), and more. The new and exciting techniques of DNA array analysis, along with such recently developed experimental methods as conformation-sensitive gel electrophoresis, are also included. Each chapter explains the basic theory behind the technique and provides valuable notes essential for its successful execution.