Related books on 'mutation-analysis'

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by: Karl Keegan
publisher: Wiley, published: 2009-01-06
ASIN: 0470511788
EAN: 9780470511787
sales rank: 283774
* The first book to provide a simple and practical means of valuing biotech companies
* The book begins with a short history of the biotechnology industry; this is important as although it is about 30 years old, the first company went public only in 1996, so it is possible to plot the course of investment waves and dips
* It examines the European industry and its evolvement, and draws parallels between the similarities and differences between that and the US
* Looks at the various companies which make up the biotech industry (therapeutic; life sciences; and the medical technology company) and gives tools for the investor to properly evaluate them

by: Ralph Weissleder MD PhD
publisher: Pmph Usa, published: 2010-06-30
ASIN: 1607950057
EAN: 9781607950059
sales rank: 835402
The field of molecular imaging of living subjects has evolved considerably and has seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: Molecular Imaging technologies , Chemistry , Molecular Imaging in Cell and Molecular Biology , Applications of Molecular Imaging , Molecular Imaging in Drug Evaluation with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

by: Shiyi Shen
publisher: Springer, published: 2010-11-19
ASIN: 3642094295
EAN: 9783642094293
sales rank: 4626422
This monograph addresses, in a systematic and pedagogical manner, the mathematical methods and the algorithms required to deal with the molecularly based problems of bioinformatics. Prominent attention is given to pair-wise and multiple sequence alignment algorithms, stochastic models of mutations, modulus structure theory and protein configuration analysis. Strong links to the molecular structures of proteins, DNA and other biomolecules and their analyses are developed.

by: R. Scott Hawley
publisher: Wiley-Blackwell, published: 2003-01
ASIN: 1405103361
EAN: 9781405103367
sales rank: 460648
Advanced Genetic Analysis brings a state-of-the-art, exciting new approach to genetic analysis. Focusing on the underlying principles of modern genetic analysis, this book provides the 'how' and 'why' of the essential analytical tools needed. The author's vibrant, accessible style provides an easy guide to difficult genetic concepts, from mutation and gene function to gene mapping and chromosome segregation. Throughout, a balanced range of model organisms and timely examples are used to illustrate the theoretical basics.

  • Basic principles - Focuses students attention on the 'how' and 'why' of the essential analytical tools.
  • Vibrant, accessible style provides an easy guide through difficult genetic concepts and techniques.
  • Text boxes highlight key questions and timely examples.
  • Boxes of key information in each chapter, chapter summaries and extensive references - prompt the student to synthesise and reinforce the chapter material.
  • Special reference section addressing a range of model organisms to help provide a particularly relevant context for students' research interests.

by: Mauro Pezze
publisher: Wiley, published: 2007-04-13
ASIN: 0471455938
EAN: 9780471455936
sales rank: 563132
The first comprehensive book on software test and analysis

You can't "test quality into" a software product, but neither can you build a quality software product without test and analysis. Software test and analysis is increasingly recognized, in research and in industrial practice, as a core challenge in software engineering and computer science. Software Testing and Analysis: Process, Principles, and Techniques is the first book to present a range of complementary software test and analysis techniques in an integrated, coherent fashion. It covers a full spectrum of topics from basic principles and underlying theory to organizational and process issues in real-world application. The emphasis throughout is on selecting a complementary set of practical techniques to achieve an acceptable level of quality at an acceptable cost.

Highlights of the book include
* Interplay among technical and non-technical issues in crafting an approach to software quality, with chapters devoted to planning and monitoring the software quality process.
* A selection of practical techniques ranging from inspection to automated program and design analyses to unit, integration, system, and regression testing, with technical material set in the context of real-world problems and constraints in software development.
* A coherent view of the state of the art and practice, with technical and organizational approaches to push the state of practice toward the state of the art.

Throughout, the text covers techniques that are suitable for near-term application, with sufficient technical background to help you know how and when to apply them. Exercises reinforce the instruction and ensure that you master each topic before proceeding.

By incorporating software testing and analysis techniques into modern practice, Software Testing and Analysis: Process, Principles, and Techniques provides both students and professionals with realistic strategies for reliable and cost-effective software development.

by: Robert Terkeltaub
publisher: Saunders, published: 2011-09-23
ASIN: 1437728642
EAN: 9781437728644
sales rank: 1298372

Gout and Other Crystal Arthropathies, by Dr. Robert Terkeltaub, presents the state-of-the-art, clinically-focused coverage you need to manage these increasingly prevalent diseases. Diagnose the full range of crystal arthropathies-including pseudogout, intercritical gout, hyperuricemia, and gouty arthritis-and treat your patients effectively with discussions of recently-approved drugs like Uloric and those currently under review, such as Kristexxa and Colcryst. With coverage of the latest therapies, preventions, and imaging studies, along with access to the fully searchable text online at www.expertconsult.com, this comprehensive resource is ideal for any physician who diagnoses, treats, and manages gout and crystal-induced arthropathies.

  • Access the fully searchable contents online at www.expertconsult.com.
  • Stay current on recent developments such as uricosuric therapy and inhibitor therapy; gout flare prophylaxis and colchicines; ultrasound in the diagnosis of crystal deposition diseases; imaging of gout, CPPD, and hydroxyapatitie deposition diseases; and uricase therapy of gout.
  • Manage the full range of crystal arthropathies with 25 clinically-focused chapters on pseudogout, intercritical gout, hyperuricemia, gouty arthritis, and more.
  • Treat your patients effectively using the latest information on drug treatments, from the recently-approved Uloric to Kristexx and Colcryst, which are still under review.

The tools to you need to diagnose, treat, and manage gout and other crystal arthropathies


publisher: Elsevier Science, published: 2001-07-24
ASIN: 044450740X
EAN: 9780444507402
sales rank: 5306641
Rapid molecular identification and typing of micro-organisms is extremely important in efforts to monitor the geographical spread of virulent, epidemic or antibiotic-resistant pathogens. It has become a mainstay of integrated hospital infection control service. In addition, numerous industrial and biotechnological applications require the study of the diversity of organisms. Conventional phenotypic identification and typing methods have long been the mainstay of microbial population and epidemiological studies, but such methods often lack adequate discrimination and their use is normally confined to the group of organisms for which they were originally devised. Molecular fingerprinting methods have flourished in recent years and many of these new methods can be applied to numerous different organisms for a variety of purposes. Standardisation of these methods is vitally important. In addition, the generation of large numbers of complex fingerprint profiles requires that a computer-assisted strategy is used for the formation and analysis of databases. The purpose of this book is to describe the best fingerprinting methods that are currently available and the computer-assisted strategies that can be used for analysis and exchange of data between laboratories.


This book is dedicated to the memory of Jan Ursing (1926 - 2000), Swedish microbiologist, taxonomist and philosopher.


"...taxonomy is on the borders of philosophy because we do not know the natural continuities and discontinuities..."


publisher: Springer, published: 2001-06-30
ASIN: 0792373235
EAN: 9780792373230
sales rank: 5826766
Extensive research and development has produce mutation tools for languages such as Fortran, Ada, C, and IDL; empirical evaluations comparing mutation with other test adequacy criteria; empirical evidence and theoretical justification for the coupling effect; and techniques for speeding up mutation testing using various types of high performance architectures. Mutation has received the attention of software developers and testers in such diverse areas as network protocols and nuclear simulation. Mutation Testing for the New Century brings together cutting edge research results in mutation testing from a wide range of researchers. This book provides answers to key questions related to mutation and raises questions yet to be answered. It is an excellent resource for researchers, practitioners, and students of software engineering.

by: John M. Butler
publisher: Academic Press, published: 2009-09-03
ASIN: 0123749999
EAN: 9780123749994
sales rank: 103284

John Butler, bestselling author of Forensic DNA Typing, now applies his expertise on the subject of DNA analysis into an introductory textbook. Fundamentals of Forensic DNA Typing walks students step-by-step through the DNA analysis process beginning with collection of evidence at a crime scene to the statistical interpretation of the results. Also included are brief discussions of such news worthy topics as victim identification from the September 11, 2001 attacks, the identification of the remains of the Romanovs, the last Russian Royal family, and the O.J. Simpson case. New applications, such as genetic genealogy and tracing domestic pet hairs to perpetrators, are also detailed. With its clear and understandable style and extensive list of online ancillaries and study aids, this textbook will make the subject accessible to students in forensic science courses worldwide.

  • Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect
  • Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout
  • Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key


by: Richard J. Reece
publisher: Wiley, published: 2004-01-26
ASIN: 0470843802
EAN: 9780470843802
sales rank: 967779
This beautifully illustrated textbook provides a clear guide to the tools and techniques of genetic engineering, gene cloning and molecular biology. All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Using an example-driven approach, the fundamentals of creating mutations in DNA, cloning in bacteria, yeast, plants and animals are all clearly presented.

Strong emphasis is placed on the latest, post genomic technologies including DNA macro and microarrays, genome-wide two hybrid analysis, proteomics and bioinformatics.

  • A modern post-genome era introduction to key techniques used in genetic engineering.
  • An example driven past-to-present approach to allow the experiments of today to be placed in an historical context
  • The book is beautifully illustrated in full-colour throughout.
  • Associated website including updates, additional content and illusions 
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