Related books on 'single-nucleotide-polymorphisms snp-analysis'
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publisher: Oxford University Press, USA, published: 2003-09-11 ASIN: 0198526156 EAN: 9780198526155 sales rank: 2286039 The Valencia International Meetings on Bayesian Statistics, held every four years, provide the main forum for researchers in the area of Bayesian Statistics to come together to present and discus frontier developments in the field. The resulting proceedings provide a definitive, up-to-date overview encompassing a wide range of theoretical and applied research. This Seventh Proceedings containing 23 invited articles and 30 contributed papers is no exception and will be an indispensable reference to all statisticians. |
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publisher: Springer, published: 2002-10-17 ASIN: 1402010095 EAN: 9781402010095 sales rank: 11110344 Volume contains the proceedings of the International Conference on Miniaturized Chemical and Biochemical Analysis Systems (uTAS), held in Nara, Japan, November 3-7, 2002. Collection of all invited and contributed papers represents the latest state-of-the-art in devices and microsystems for chemical and biochemical applications. |
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by: Dimitri Semizarov publisher: Wiley, published: 2008-11-03 ASIN: 0470096047 EAN: 9780470096048 sales rank: 2341964 Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative advantages and disadvantages, including microarray data analysis, Genomics in Drug Discovery and Development introduces readers to the biomarker, pharmacogenomic, and toxicogenomics toolbox. The authors provide a valuable resource for pharmaceutical discovery scientists, preclinical drug safety department personnel, regulatory personnel, discovery toxicologists, and safety scientists, drug development professionals, and pharmaceutical scientists. |
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by: Royal Society of Chemistry publisher: Royal Society of Chemistry, published: 2010-10-18 ASIN: 1847559115 EAN: 9781847559111 sales rank: 2801130 This unique introduction to the growing field of microfluidics applied to genomics provides an overview of the latest technologies and emphasizes its potential in answering important biological questions. Written by a physicist and a biologist, it offers a more comprehensive view than the previous literature. The book starts with key ideas in molecular biology, developmental biology and microtechnology before going on to cover the specifics of single cell analysis and microfluidic devices for single cell molecular analysis. Review chapters discuss the state-of-the art and will prove invaluable to all those planning to develop microdevices for molecular analysis of single cells. Methods allowing complete analysis of gene expression in the single cell are stressed - as opposed the more commonly used techniques that allow analysis of only a few genes at a time. As pioneers in the field, the authors understand how critical it is for a physicist to understand the biological issues and questions related to single cell analysis, as well for biologists to understand what microfluidics is all about. Aimed predominantly at graduate students, this book will also be of significant interest to scientists working in or affiliated with this field.
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by: Robert S. Matson publisher: CRC Press, published: 2009-01-20 ASIN: 1420046659 EAN: 9781420046656 sales rank: 2768682 A Step-by-Step Guide to Present and Future Uses of Microarray Technology Microarray technology continues to evolve, taking on a variety of forms. From the spotting of cDNA and the in situ synthesis of oligonucleotide arrays now come microarrays comprising proteins, carbohydrates, drugs, tissues, and cells. With contributions from microarray experts in both academia and industry, Microarray Methods and Protocols is a turn-by-turn roadmap through the processes necessary to perform a successful microarray experiment. This easy to use book addresses the fundamental aspects of preparing and processing microarrays and bead arrays, labeling, and detection. It also includes a detailed How it Works section that discusses the underlying principles of a number of techniques. Troubleshooting guides offer additional advice for the successful performance of more than 100 protocols in 10 chapters that cover work involving nucleic acids, proteins, carbohydrates, and lectins. --Concise and Well-Organized-- With a focus on the preparation and use of microarrays of biomedical relevance, the text describes a variety of microarray formats useful in the assessment of human disease and in genomic and proteomic research. This authoritative resource provides detailed information regarding sample preparation, labeling, array construction processes, substrate chemistry, array printing, and quality control. Originating with the glass microscope slide and biochip, microarray technology is now pressing onward into the nanotechnology frontier. This book is the all-inclusive manual scientists need to take microarray research to the next level of discovery. |
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by: Susanne Hummel publisher: Springer, published: 2010-12-08 ASIN: 3642077056 EAN: 9783642077050 sales rank: 4008962 This is the definitive source of information on techniques for the identification and sequencing of old DNA (pieces) and their use in biological and medical research and application. Application of aDNA techniques are useful tools for investigations reaching from evolutionary studies to law enforcement approaches. What brings them together is the interest in specific methods of handling aDNA, i.e. elaborated PCR and sequencing techniques and the interpretation of the results. This books serves as an ideal guideline for it demonstrates how problem-solving strategies can be applied in various areas. |
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publisher: Springer, published: 2006-02-07 ASIN: 0387293426 EAN: 9780387293424 sales rank: 4526171 This third volume in the serial Reviews in Fluorescence is a collection of up to 10 invited reviews on current trends and emerging hot topics in fluorescence. This new annual series compliments the other fluorescence titles published by Springer, while feeding the requirement from the fluorescence community for annual informative updates and developments. |
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by: Michael J. Corey publisher: Wiley, published: 2008-12-10 ASIN: 0470108835 EAN: 9780470108833 sales rank: 3856106 This book highlights the applications of coupled bioluminescence assay techniques to real-world problems in drug discovery, environmental and chemical analysis, and biodefense. It separates theoretical aspects from the applied sections in a clear and readable way. Coupled Bioluminescent Assays, explains the uses of CB technologies across drug discovery to analyze toxicity, drug receptors, and enzymes. It covers applications in environmental analysis and biodefense, including cytotoxicity, fertilizer and explosives analysis, and nerve agent and pesticide detection. This is the premier reference on coupled bioluminescent assays for chemists, biochemists, and molecular biologists. |
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publisher: Springer, published: 2010-10-27 ASIN: 9048193818 EAN: 9789048193813 sales rank: 3899584 DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients. Recent developments are presented concerning the isolation, quantification and analysis of these molecules and their use in the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis. |
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publisher: Springer, published: 2004-03-05 ASIN: 3540207791 EAN: 9783540207795 This book constitutes the refereed proceedings of the 30th Conference on Current Trends in Theory and Practice of Computer Science, SOFSEM 2004, held in Merín, Czech Republic, in January 2004. The volume presents 10 invited lectures and 22 full papers selected from 136 submissions. Among the topics covered are computer science theory, programming theory, database systems, information systems, cognitive technologies and Web technologies. |