Related books on 'single-nucleotide-polymorphisms'
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publisher: Biotech Patent News, published: 2001-01-01 ASIN: B0008HPNRK This digital document is an article from BIOTECH Patent News, published by Biotech Patent News on January 1, 2001. The length of the article is 435 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Promega receives genomics patent for innovative Snp scoring method.(single nucleotide polymorphism)(Brief Article) Publication: BIOTECH Patent News (Newsletter) Date: January 1, 2001 Publisher: Biotech Patent News Volume: 15 Issue: 1 Page: NA Article Type: Brief Article Distributed by Thomson Gale |
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publisher: Biotech Patent News, published: 2001-05-01 ASIN: B0008HYHFO This digital document is an article from BIOTECH Patent News, published by Biotech Patent News on May 1, 2001. The length of the article is 449 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser. Citation Details Title: Genome Therapeutics presents high-throughput SNP assay.(Exo-Proofreading single-nucleotide polymorphism Assay)(Brief Article) Publication: BIOTECH Patent News (Newsletter) Date: May 1, 2001 Publisher: Biotech Patent News Volume: 15 Issue: 5 Page: NA Article Type: Brief Article Distributed by Thomson Gale |
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by: H. Kinoshita publisher: Elsevier ASIN: B000RR71DK This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser. Description: The principle of hybridizing oligonucleotides is employed with single nucleotide polymorphisms (SNPs) typing, but that typing frequently failed. We investigated the SNPs typing of multi-alleles on a chip. Two bases adjacent to the SNPs on the immobilized oligonucleotide probes were substituted for the 2'-deoxyinosine (dI) residues. The biotinylated probes containing the partial sequence of CYP2C9, CYP2C19, GLC1A and ApoE alleles were applied to the streptavidin-embedded plasma-polymerized (PP) DNA microarrays. For the probes containing dI, up to a 2-5-fold difference in the match to a mismatch oligonucleotide fluorescence intensity was found as the probes without dI were 1.5-fold or less. According to the substitution for dI, the hybridization accuracy was enhanced, and then several single-base mismatches were detected on a chip. |
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by: Marco A.B. Mansur publisher: Biomedical Informatics Publishing Group, published: 2008-01-01 ASIN: B0026BXB34 This digital document is an article from Bioinformation, published by Biomedical Informatics Publishing Group on January 1, 2008. The length of the article is 732 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser. From the author: Keywords: software; single nucleotide polymorphisms; multiple sequence alignment; ClustalW Citation Details Title: SNUFER: a software for localization and presentation of single nucleotide polymorphisms using a Clustal multiple sequence alignment output file.(Software) Author: Marco A.B. Mansur Publication: Bioinformation (Magazine/Journal) Date: January 1, 2008 Publisher: Biomedical Informatics Publishing Group Page: 63(2) Distributed by Gale, a part of Cengage Learning |
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by: Eric Christian Rouchka publisher: Biomedical Informatics Publishing Group, published: 2008-01-01 ASIN: B0026BXBH0 This digital document is an article from Bioinformation, published by Biomedical Informatics Publishing Group on January 1, 2008. The length of the article is 4042 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser. From the author: Keywords: Affymetrix HG-U133A; single nucleotide polymorphism; microarray; probe; mismatch Citation Details Title: Effect of single nucleotide polymorphisms on Affymetrix[R] match-mismatch probe pairs.(Hypothesis) Author: Eric Christian Rouchka Publication: Bioinformation (Magazine/Journal) Date: January 1, 2008 Publisher: Biomedical Informatics Publishing Group Page: 405(7) Distributed by Gale, a part of Cengage Learning |
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publisher: CRC Press, published: 2006-12-05 ASIN: 0849396689 EAN: 9780849396687 sales rank: 2555969 Since the last major compendium dedicated to cyclic nucleotide phosphodiesterases (PDEs) was published over 15 years ago, an enormous amount of progress has occurred in the field. There is great need for a centralized source for key information in this burgeoning and therapeutically important area of medical research. Cyclic Nucleotide Phosphodiesterases in Health and Disease provides an integrated volume covering PDE biology from genes to organisms. It examines phosphodiesterases as pharmacological targets as well as the development of specific PDE inhibitors as therapeutic agents. With contributions from pioneers in the field, individual chapters describe one of the 11 known mammalian PDE families including the molecular characteristics, structure, function, and traits unique to each. Characteristics of PDEs from lower organisms are also the subject of other chapters since they provide key insights into PDE functions and are also pharmacological targets for treatment of a variety of diseases in humans and domestic animals. Chapters on the current biomedical and therapeutic research on PDEs include studies on gene-targeted knockout strategies and compartmentation in cyclic nucleotide signaling. By unraveling the unique cellular roles for different PDEs, scientists are beginning to open the door to the therapeutic use of PDE inhibitors for the treatment of a number of pathological conditions including asthma and inflammation, pulmonary hypertension, erectile dysfunction, and stroke. By collating current information into a coherent and coordinated perspective, Cyclic Nucleotide Phosphodiesterases in Health and Disease provides an invaluable reference for industry and clinical scientists and points toward future directions of research and therapeutic advancements in developing selective inhibitors for these various enzymes. |
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publisher: CRC Press, published: 2005-06-23 ASIN: 0824753429 EAN: 9780824753429 sales rank: 4452234 While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing analytical technology that has permitted us entry into the genomic era and a whole new level of scientific understanding. Analytical Techniques in DNA Sequencing takes a look at the various DNA sequencing techniques that were developed and put to use during and after the Human Genome Project. Nunnally makes a special effort to trace the development of this branch of research since the early days of radioisotope sequencing. Special attention is paid to the breakthrough Sanger Method (1977), as well as to several other techniques that improved the accuracy, improved the detection limits, and in a variety of ways dramatically reduced the time needed to generate a DNA sequence. This comprehensive volume describes the improvements in DNA separation based on advanced capillary electrophoresis and microchip sequencing. It also looks at the use of mass spectrometry and single molecule detection, and takes an in-depth look at the use of various fluorescence methods for the detection of sequencing fragments. One chapter is dedicated to chip-based microfabricated sequencing systems, which could well be the future of DNA sequencing. The book’s ten chapters, authored by a variety of leading experts in the field, include many of the far-reaching applications of DNA sequencing. Entire chapters are dedicated to DNA typing for forensics, a reevaluation of ancient DNA, and genome analysis. |
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publisher: World Scientific Pub Co Inc, published: 2000-07-04 ASIN: 1860941966 EAN: 9781860941962 sales rank: 9278966 This volume uses selected molecules expressed on erythrocytes, lymphocytes, platelets and granulocytes to illustrate how genetic polymorphisms and variations in these molecules can affect their structure and function in mature human blood cells. Examples given and described tend to have a clinical association. |
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by: Peter Libby MD publisher: Saunders, published: 2007-10-19 ASIN: 1416041060 EAN: 9781416041061 sales rank: 457410 Dr. Braunwald's masterwork returns ... bringing you the definitive guidance you need to overcome any challenge in clinical cardiology today, using the best approaches available! Hundreds of world authorities, many of them new to this edition, synthesize all of the recent developments that are revolutionizing practice - from the newest findings in molecular biology and genetics to the latest imaging modalities, interventional procedures, and medications. The expertise of the book's contributors, the scope of its coverage, and its richly illustrated, user-friendly format all make this the ultimate reference for the practicing cardiologist.
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by: Anthony S. Fauci publisher: McGraw-Hill Professional, published: 2008-03-06 ASIN: 0071466339 EAN: 9780071466332 sales rank: 47988 Introducing the most dramatically revised edition of Harrison's ever! Now with NEW bonus DVD with 37 chapters and more than 500 brand new images and video clips! A Doody's Core Title ESSENTIAL PURCHASE! 5 STAR DOODY'S REVIEW MORE THAN TRUSTED, BEYOND ESSENTIAL . . . The #1 selling medical textbook worldwide, Harrison's has defined internal medicine for millions of clinicians and students. The new 17th Edition retains Harrison's acclaimed balance of pathobiology, cardinal signs and manifestations of disease, and best approaches to patient management, yet has been massively updated to give you an innovative array of bold new features and content. If ever there was one must-have resource for clinicians and students -- this is it! UNMATCHED EXPERTISE AT YOUR FINGERTIPS As an unprecedented amount of medical information bombards you and your patients, where do you go to sort it out and make sense of it all? When your patients request clarification on something they've “printed off,” where do you turn for expert explanations? The same trusted resource physicians and students have turned to for more than fifty years: Harrison's Principles of Internal Medicine. Now more than ever, trust Harrison's to filter and clarify the exploding knowledge base, to highlight the breakthroughs, and to deliver a clear, balanced distillation of the best and most current information on which to base clinical decisions. THE MOST EXCITING AND EXTENSIVELY REVISED EDITION EVER! Here are just a few of the reasons why the new 17th Edition of Harrison's is the best edition yet:
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