Related books on 'tissue-microarray'
Return to life science book listNumber of products: 1358
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publisher: Humana Press, published: 2010-11-19 ASIN: 1617376639 EAN: 9781617376634 sales rank: 6518286 Microarray Technology, Volumes 1 and 2, present information in designing and fabricating arrays and binding studies with biological analytes. This is done while providing the reader with a broad description of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments. Microarray Technology, Volumes 1 and 2, provide ample information to all levels of scientists from novice to those intimately familiar with array technology. |
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by: Noreen Clancy publisher: Rand Publishing, published: 2003-12-16 ASIN: 0833035274 EAN: 9780833035271 sales rank: 2520772 Case studies of twelve existing human biospecimen repositories performed to evaluate their utility for genomics- and proteomics-based cancer research and to identify "best practices" in collection, processing, annotation, storage, privacy, ethical concerns, informed consent, business plans, operations, intellectual property rights, public relations, marketing, and education that would be useful in designing a national biospecimen network. |
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publisher: Springer, published: 2006-12-04 ASIN: 0387399771 EAN: 9780387399775 sales rank: 4163893 Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated. This book, written by leading experts, discusses the technical features characterizing the powerful laboratory tool of microarray technology, and reviews applications in the field of oncology. |
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by: Gary Hardiman PhD publisher: Dna Press, published: 2003-06 ASIN: 0966402766 EAN: 9780966402766 sales rank: 3256677 The confluence of robotics, biotechnology, computer sciences and the completion of genome sequencing efforts for several organisms have resulted in revolutionary changes in how biomedical research is carried out. In recent years high-density arrays of specified DNA sequences have gained in popularity. Genomics and informatics are playing increasingly important roles as discovery tools in the basic biological sciences, and as diagnostic and rational therapeutic aids in the clinical arena. The genesis of this publication was a microarray workshop organized by Dr. Gary Hardiman and The Department of Bioscience at The University of California San Diego Extension. Gary Hardiman is the Director of BIOGEM (an organized research unit and core facility) specializing in high throughput genomic approaches, including DNA microarray technology and bioinformatics. He also teaches at the University of California San Diego Extension (Bioscience) Drug Discovery and Development Professional Certificate Program. The combination of his experience at a core facility and teaching obligations has contributed to the publication of a book that serves both as a practical laboratory manual and a class reference for teaching microarray technology. The book provides both an introduction and detailed overview of microarray technologies in academic and industrial settings. It examines evolving technology standards for microarray research, explores automation and instrumentation in the array laboratory, and discusses in detail the set up and operation of a microarray core facility. |
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by: Hans-Joachim Müller publisher: Academic Press, published: 2005-12-06 ASIN: 0120885433 EAN: 9780120885435 sales rank: 3455552 Microarrays is an invaluable laboratory manual for anyone conducting experiments in the field of molecular biology or medical biochemistry who needs to understand and use microarray technologies. These technologies are especially appropriate in genome analysis, diagnostics, and studies involving differential gene expression. Providing straightforward explanations, the authors demonstrate proven methods for biochip application and an overview of presently available instruments, biochips, and software. Chapters cover the different requirements for DNA and protein chips, as well as spotters and scanners. The book also covers high throughput screening, patent research, and the minimum requirements for setting up or expanding a microarray laboratory. · Covers microarray applications, technology, and execution · Written in an approachable yet informative tone · Includes more than 100 detailed figures and graphs · Examines the history of microarrays and their future potential · Defines key terms from related disciplines · Contains a full chapter on the importance of database research and patents · Describes how to develop or improve one's own microarray laboratory |
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by: Steen Knudsen publisher: Wiley-Liss, published: 2006-09-11 ASIN: 0471784079 EAN: 9780471784074 sales rank: 3672857 Authored by an international authority in the field,Cancer Diagnostics with DNA Microarrays is a complete reference work on the rapidly growing use of DNA microarray data in the diagnosis of and treatment planning for a large number of human cancers.
Replete with examples and mini-cases, Cancer Diagnostics with DNA Microarrays offers cancer researchers in private, pharmacologic, and governmental institutions, biomedical statisticians, and practicing oncologists concise, thoughtfully authored guidance on the use of microarray data and analysis as clinical tools. The text carefully addresses the needs of end users – researchers and physicians – using microarrays as a tool to be applied in common clinical situations, and is of interest for students in medicine and biology and professionals in health care as well. |
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publisher: Springer, published: 2011-01-24 ASIN: 3642095100 EAN: 9783642095108 sales rank: 4367394 Multimodal treatment lies at the heart of the improvement in cancer cure rates. However, the more aggressive the treatment, the more adverse effects in normal tissues can be anticipated. Against this background, a major paradigm shift has taken place in that there is a new focus on cancer survivorship and quality of life: the life worth saving must be worth living. This volume is based on the CURED II conference held in May 2007, which was attended by scientists from many leading institutions. The volume comprises 18 chapters by leading experts who address a variety of important topics relating to late treatment effects, such as mechanisms and evolution of injury, risk factors, the role of screening, options for interventions, second malignancies, and prevention. It is hoped that it will assist the reader in understanding how to prevent and treat the long-term side-effects of irradiation, thus improving the quality of life of long-term survivors of cancer. |
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publisher: Springer, published: 2010-11-10 ASIN: 9048176387 EAN: 9789048176380 sales rank: 6233190 This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways. |
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publisher: Academic Press, published: 2006-09-11 ASIN: 0121828158 EAN: 9780121828158 sales rank: 1986180 Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician. · Provides an overview of platforms · Includes experimental design and wet bench protocols · Presents statistical and data analysis methods, array databases, data visualization and meta analysis |
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by: Wei Zhang publisher: Wiley-Liss, published: 2004-03-04 ASIN: 0471453447 EAN: 9780471453444 sales rank: 4086374 Microarray technology provides researchers in the life sciences with a revolutionary tool for measuring gene expression. However, this highly developed process involves multiple steps, from sample selection to data analysis, each susceptible to potentially costly errors. Without sound quality control, experimental microarrays may produce useless or, even worse, misleading results. Microarray Quality Control provides a comprehensive resource for ensuring quality control in every step of this complex process. From experimental design to data processing, analysis, and interpretation, the emphasis in this text remains on practical advice for each stage of planning and running a microarray study. Chapters cover: * Quality of biological samples * Quality of DNA * Hybridization protocols Scanning * Data acquisition * Image analysis * Data analysis Written for the broad group of workers-biologists, mathematicians, statisticians, engineers, physicians, and computational scientists-involved in microarray studies, Microarray Quality Control features a straightforward style easily accessed by various disciplines. Useful checklists and tips help ensure the integrity of results, and each chapter contains a thorough review of pertinent literature. The only complete, systematic treatment of the topic available, Microarray Quality Control offers students and practitioners an invaluable resource for improving experimental quality and efficiency. |