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by: Andrea L. Bonnicksen
publisher: Georgetown University Press, published: 2009-09-21
ASIN: 1589015746
EAN: 9781589015746
sales rank: 1680270
In his 2006 State of the Union speech, President George W. Bush asked the U.S. Congress to prohibit the "most egregious abuses of medical research," such as the "creation of animal--human hybrids." The president's message echoed that of a 2004 report by the President's Council on Bioethics, which recommended that hybrid human--animal embryos be banned by Congress. Discussions of early interspecies research, in which cells or DNA are interchanged between humans and nonhumans at early stages of development, can often devolve into sweeping statements, colorful imagery, and confusing policy. Although today's policy advisory groups are becoming more informed, debate is still limited by the interchangeable use of terms such as chimeras and hybrids, a tendency to treat all forms of interspecies alike, the failure to distinguish between laboratory research and procreation, and not enough serious policy justification. Andrea Bonnicksen seeks to understand reasons behind support of and disdain for interspecies research in such areas as chimerism, hybridization, interspecies nuclear transfer, cross-species embryo transfer, and transgenics. She highlights two claims critics make against early interspecies studies: that the research will violate human dignity and that it can lead to procreation. Are these claims sufficient to justify restrictive policy? Bonnicksen carefully illustrates the challenges of making policy for sensitive and often sensationalized research -- research that touches deep-seated values and that probes the boundary between human and nonhuman animals.
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publisher: Springer, published: 2010-11-25
ASIN: 3642068812
EAN: 9783642068812
Tree improvement is necessary to meet the growing demand for renewable wood resource and the time is ripe for a critical evaluation of the chances and challenges of tree transgenesis. This book provides an up-to-date review of the present state of genetic engineering of trees. Biosafety and risk assessment are treated in detail, and future experimental tasks are discussed. The book provides a sound basis for decision-making processes in politics.
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publisher: Springer, published: 1998-05-15
ASIN: 3540637125
EAN: 9783540637127
sales rank: 9802767
This book presents the latest in mammary gland transgenesis, the exploitation of transgenic technology for the production of therapeutic proteins by routine or conventional methods. Following a section with an overview of all relevant methodologies, readers will find relevant information on the regulation of milk gene expression and bioreactor species such as cattle, rabbits and pigs.
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by: David Murphy
publisher: Humana Press, published: 1993-01-15
ASIN: 0896032450
EAN: 9780896032453
sales rank: 8773201
Practical methods for the generation and analysis of transgenic animals, covering a comprehensive range of species, from invertebrates to lower vertebrates to higher vertebrates. Chapters examine ways in which transgenic techniques can be used to address many problems in biological systems present in-depth descriptions of analytical methods, and give step-by-step techniques that can be easily performed in your lab.
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publisher: Humana Press, published: 2009-06-29
ASIN: 1603270183
EAN: 9781603270182
sales rank: 143812
One of the major challenges currently facing the scientific community is to understand the function of the multitude of protein-coding genes that were revealed when the human genome was fully sequenced. In Transgenesis Techniques: Principles and Protocols, Third Edition, experts in the field fully update and expand upon the previous edition in order to detail the transgenic techniques currently used to modify the genome. The volume explores classic procedures to genetically modify mice and other model organisms, as well as cutting-edge practices involving microinjection, site-specific recombination systems, cryopreservation, and many other topics. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes sections, highlighting tips on troubleshooting and avoiding known pitfalls. Comprehensive and state-of-the-art, Transgenesis Techniques: Principles and Protocols, Third Edition is a comprehensive practical guide to the generation of transgenic animals and an invaluable source of information in any lab currently involved in transgenic techniques.
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publisher: Birkhäuser Basel, published: 2003-07-09
ASIN: 3764352620
EAN: 9783764352622
sales rank: 7148392
This selected collection of contributions focuses on the modification of organisms through genetic manipulation. Scientists from various disciplines assess the quality of our knowledge on which risk assessment of gene technology methods is currently based. Molecular biology and ecology, but also aspects of evolutionary and population genetics, human genetics and genetically modified food are among the topics covered. The book analyzes the impetus behind, and progress in, research methods which have been introduced into gene-technology risk assessment procedures over the last three years, and, in so doing, reveals gaps in our understanding of evolutionary processes. The history of risk assessment and ethical implications with respect to the deliberate release of GMOs are considered. Finally, the transfer of knowledge from the laboratory to the public, and the role of the media in this process are discussed. This monograph will be of great interest to all those concerned with the risk assessment of genetechnology methods.
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publisher: Springer, published: 1999-08-13
ASIN: 3540651209
EAN: 9783540651208
sales rank: 9741566
Comprising 26 chapters, this volume deals with the genetic transformation of medicinal plants. It describes methods to obtain plants resistant to insects, diseases, herbicides, and plants with an increased production of compounds of medicinal and pharmaceutical importance. The plant species included are Ajuga reptans, Anthemis nobilis, Astragalus spp., Atropa belladonna, Catharanthus roseus, Datura spp., Duboisia species, Fagopyrum spp., Glycyrrhiza uralensis, Lobelia spp., Papaver somniferum, Panax ginseng, Peganum harmala, Perezia spp., Pimpinella anisum, Phyllanthus niruri, Salvia miltiorrhiza, Scoparia dulcis, Scutellaria baicalesis, Serratula tinctoria, Solanum aculeatissimum, Solanum commersonii, Swainsona galegifolia, tobacco, and Vinca minor. This book is of special interest to advanced students, teachers, and researchers in the field of pharmacy, plant tissue culture, phytochemistry, molecular biology, biomedical engineering, and plant biotechnology in general.
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publisher: Springer, published: 2010-11-10
ASIN: 3642071805
EAN: 9783642071805
This volume presents the current knowledge of plant biotechnology as an important tool for crop improvement. It covers cereals, vegetables, root crops, herbs and spices. This volume is an invaluable reference for plant breeders, researchers and graduate students in the fields of plant biotechnology, agronomy, horticulture, genetics and both plant cell and molecular biology.
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publisher: Springer, published: 2009-08-11
ASIN: 3540938680
EAN: 9783540938682
National, European and international concepts and strategies concerning the legal and ethical framework of chimera and hybrid research are still largely missing, even though they are absolutely necessary in order to use the potential of chimera and hybrid research effectively and efficiently for the benefit of science and society. The outcome of the CHIMBRIDS-Project successfully sheds light on the chances and risks of this research and provides legal solutions to existing problems in order to help decision-makers fulfil their tasks in an informed and efficient manner. This comprehensive volume details the complete results, contributed by 40 scholars from 10 member states of the European Union, Canada, China, Israel, Japan, Switzerland and the US, with descriptive reports of the legal situation in specific countries and in-depth analysis of all scientific, medical, ethical and legal implications of chimera and hybrid research.
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by: Carl A. Pinkert
publisher: Academic Press, published: 2002-12-02
ASIN: 0125571666
EAN: 9780125571661
sales rank: 2464630
Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions. This well-illustrated handbook covers the technical aspects of gene transfer - from molecular methods to whole animal considerations - for important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a tool for training technicians and students. This second edition incorporates updates on a variety of genetic engineering technologies ranging from microinjection and ES cell transfer to nuclear transfer in a broad range of animal modeling systems.
Contains a comprehensive collection of transgenic animal and gene transfer methods Discusses background and introduction to techniques and animal systems Teaches practical step-by-step protocols New section on analysis
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