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publisher: Taylor & Francis, published: 1996-03-12
ASIN: 0748404449
EAN: 9780748404445
sales rank: 7257522
In apoptosis in the mammalian system, cells have a finite life - they develop, are used and then die. Cancer cells escape this programmed routine but, from an understanding of apoptosis, they can be programmed to die. This book addresses the
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publisher: CRC, published: 1999-12-02
ASIN: 0748408150
EAN: 9780748408153
sales rank: 5781415
Apoptosis in Toxicology is the first book to focus on the molecular regulation of apoptosis with particular emphasis on toxicant action. Cell survival signalling and its perturbation is addressed at the genetic and biochemical level, including key survival and death genes, survival signalling, commitment to apoptosis and recruitment of the initiator and executioner caspases. Emphasis is given to the role apoptosis plays in the action of toxicants in the brain, the immune system, the reproductive organs, the kidney and the liver. The ability of drugs to regulate apoptosis either as a target or as an adverse effect is discussed with particular reference to cancer chemotherapy. The many methods that can be employed to quantify apoptosis are compared and their application to different tissues is discussed. This timely and comprehensive volume has been written by leading authorities and active researchers in their respective fields. It will have broad appeal to toxicologists, physicians and biologists across many disciplines.
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publisher: Humana Press, published: 1997-04-15
ASIN: 0896034518
EAN: 9780896034518
sales rank: 5548938
An indispensable compendium of state-of-the-art theory and detailed how-to instruction essential for understanding and studying apoptosis. The expert contributors cover such important topics as the histological, biological, and molecular criteria for apoptosis and programmed cell death; necrosis and apoptosis in the CNS; and cellular, invertebrate, animal, and human models of apoptosis in Alzheimer's disease, AIDS, and stroke. The techniques they describe examine the critical steps involved in the apoptosis process, and include PCR analysis of cell-cycle-regulated proteins, histochemical analysis of DNA regulation, DNA laddering analysis, and cytochemical alterations of living cells.
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by: Icon Group International
publisher: ICON Group International, Inc., published: 2009-07-10
ASIN: 111401530X
EAN: 9781114015302
Webster's bibliographic and event-based timelines are comprehensive in scope, covering virtually all topics, geographic locations and people. They do so from a linguistic point of view, and in the case of this book, the focus is on "Apoptosis-Inducing," including when used in literature (e.g. all authors that might have Apoptosis-Inducing in their name). As such, this book represents the largest compilation of timeline events associated with Apoptosis-Inducing when it is used in proper noun form. Webster's timelines cover bibliographic citations, patented inventions, as well as non-conventional and alternative meanings which capture ambiguities in usage. These furthermore cover all parts of speech (possessive, institutional usage, geographic usage) and contexts, including pop culture, the arts, social sciences (linguistics, history, geography, economics, sociology, political science), business, computer science, literature, law, medicine, psychology, mathematics, chemistry, physics, biology and other physical sciences. This "data dump" results in a comprehensive set of entries for a bibliographic and/or event-based timeline on the proper name Apoptosis-Inducing, since editorial decisions to include or exclude events is purely a linguistic process. The resulting entries are used under license or with permission, used under "fair use" conditions, used in agreement with the original authors, or are in the public domain.
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publisher: Gazelle Distribution, published: 2006-09-06
ASIN: 160021424X
EAN: 9781600214240
sales rank: 9828211
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer.Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book presents exciting research in this related field.
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publisher: Gazelle Distribution, published: 2006-10-29
ASIN: 1600214509
EAN: 9781600214509
sales rank: 10003735
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer.A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. The aim of this book is to provide new studies in the field of apoptosis research.
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publisher: Nova Science Pub Inc, published: 2007-10-29
ASIN: 1600215653
EAN: 9781600215650
sales rank: 6240678
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer s disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book focuses on cell apoptotic signalling.
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publisher: Springer, published: 1996-04-12
ASIN: 354058756X
EAN: 9783540587569
sales rank: 10736758
This book covers apoptosis or programmed cell death of B and T lymphocytes and their precursors, providing recent conceptual insights into the complex field of apoptosis regulation in normal and pathological situations. Written by leading experts in the field, each chapter offers a succinct state-of-the-art review, emphasizing the conceptual integration of data over their mere accumulation. The reader will profit from a collection of outstanding surveys that cover both fundamental and practical aspects of lymphocyte apoptosis. In the era of molecular biology, the immunologically interested public should be aware of the enormous importance of apoptosis for immune homeostasis. This volume provides an ideal introduction.
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publisher: Springer, published: 2000-02-29
ASIN: 3540661212
EAN: 9783540661214
sales rank: 6260017
This book is concernced with the process of cell death in human cells by programmed cell death or apoptosis, and the modulation of this process by drugs. This is a new field of study and this volume represents the first comprehensive treatment of this subject matter. Its focus is on human biology and medicine. Apoptosis is a very prevalent type of cell death with importance in human diseases such as cancer, Alzheimer's disease and autoimmune disorders. The book combines the expertise of leading scientists and writers from fields as diverse as neurosciences, immunology, pathology and cancer research. There is detailed analysis of the molecular and cellular aspects of apoptosis including the specific genes and molecules involved in the regulation of this special form of programmed cell death. Scientists, clinicians and researchers involved in studies of human biology and medicine will find this book an excellent resource.
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publisher: Birkhäuser Basel, published: 1999-07-30
ASIN: 3764357959
EAN: 9783764357955
sales rank: 7889662
Apoptosis is a form of cell death that occurs in a controlled manner and is generally noninflammatory in nature. Apoptosis, or programmed cell death, implies a cell death that is part of a normal physiological process of pruning of unneeded cells. However, many disease conditions utilize apoptosis for pathological ends, resulting in inappropriate cell death and tissue destruction. This book starts with an introduction that reviews the general characteristics of apoptosis, its regulation and its role in physiology and disease. Next, the book focuses on three areas as they relate to inflammatory cells and diseases. The first area consists of chapters on signals for apoptosis important to inflammatory cells, namely growth factors and arachidonic acid metabolism. The next area that the book focuses on are effects at the cellular level, on cell survival versus cell death and signals critical for cell function in both normal and disease states. These topics are covered in chapters on lymphocytes, granulocytes, chondrocytes and keratinocytes. The last area that the book focuses on are events at the level of tissue and disease, looking at the evidence for altered apoptosis and/or apoptotic processes in immune and inflammatory diseases. These topics are covered in chapters on rheumatoid arthritis, osteoarthritis, lupus, psoriasis and renal disease. Together, these chapters will provide the reader with the latest insight in the role of apoptosis in inflammatory cells and diseases. This book starts with an introduction that reviews the general characteristics of apoptosis, its regulation and its role in physiology and disease. Next, the book focuses on three areas as they relate to inflammatory cells and diseases. The first area consists of chapters on signals for apoptosis important to inflammatory cells, namely growth factors and arachidonic acid metabolism. The next area that the book focuses on are effects at the cellular level, on cell survival versus cell death and signals critical for cell function in both normal and disease states. These topics are covered in chapters on lymphocytes, granulocytes, chondrocytes and keratinocytes. The last area that the book focuses on are events at the level of tissue and disease, looking at the evidence for altered apoptosis and/or apoptotic processes in immune and inflammatory diseases. These topics are covered in chapters on rheumatoid arthritis, osteoarthritis, lupus, psoriasis and renal disease. Together, these chapters will provide the reader with the latest insight in the role of apoptosis in inflammatory cells and diseases.
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