Related books on 'epigenetics chromatin'
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publisher: Wiley, published: 2009-10-20 ASIN: 0470758619 EAN: 9780470758618 sales rank: 2447569 The role of epigenetic mechanisms in autoimmune disease is only now starting to become clear. Understanding these mechanisms, their effect on cellular function and the role of environmental factors is vital to determining how to manage these often debilitating and fatal diseases. Drawing on the research of leading experts, this book provides a valuable insight into this important new area of autoimmunity research and a clear, up-to-date view on the major advances in the field. Specific coverage includes:
This book is an essential resource for those actively involved in the field. It is also of interest to basic researchers interested in understanding the origin of autoimmunity and clinical specialists interested in gaining in-depth understanding of the pathogenesis of autoimmune diseases and their treatment. |
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publisher: Springer, published: 2005-05-25 ASIN: 3540233725 EAN: 9783540233725 sales rank: 1834266 Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence. This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other. |
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publisher: Academic Press, published: 2010-10-28 ASIN: 0123808642 EAN: 9780123808646 sales rank: 3165100 Genes interact with environment, experience, and the biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity. * Explores latest topics in neural circuits and behavior research in zebrafish, drosophila, c.elegans, and mouse models * Includes methods for testing with ethical, legal, and social implications * Critically analyzes prospects future prospects |
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publisher: Springer, published: 2003-02-12 ASIN: 3540442081 EAN: 9783540442080 sales rank: 4559234 This book provides timely reviews of several protein complexes that regulate gene expression and chromatin dynamics. Examples of such complexes include: nucleosome assembly complexes, ATP-dependent chromatin remodeling complexes, histone acetyltransferase complexes, histone deacetylase complexes, heterochromatin complexes, SMC complexes and transcription elongation complexes. These chapters will bring experts in the field up to date on several aspects of chromosome biology and will provide an exiting introduction to the field for new chromatin researchers. |
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publisher: Academic Press, published: 2011-03-11 ASIN: 0123820324 EAN: 9780123820327 sales rank: 978563 Reproductive toxicology is a complex subject dealing with three components-parent, placenta, and fetus-and the continuous changes that occur in each. Reproductive and Developmental Toxicology is a comprehensive and authoritative resource providing the latest literature enriched with relevant references describing every aspect of this area of science. It addresses a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, and metals, among others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, and is the only resource to include reproductive and developmental toxicity in domestic animals, fish, and wildlife. * Provides a complete, integrated source of information on the key risk stages during reproduction and development * Includes coverage of emerging science such as stem cell application, toxicoproteomics, metabolomics, phthalates, infertility, teratogenicity, endocrine disruption, surveillance and regulatory considerations, and risk assessment * Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis |
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publisher: Wiley-VCH, published: 2010-01-19 ASIN: 3527324275 EAN: 9783527324279 sales rank: 1278250 "... The editors have succeeded in compiling some fascinating aspects of epigenetic control mechanisms. The book can be recommended to everyone enjoying a profound intellectual insight into facets of conventional genetics and molecular biology and varied influences of lifestyle and the environment." —Pharmazie in unserer Zeit (review in German) The consequences of hereditary factors on human health and their interaction with environmental, nutritional and life style factors are topics which are at the center of public, governmental and scientific interest. This handbook and ready reference work features an holistic introduction by Paolo Vineis and 19 contributions from leading scientists. After introducing the concept of epigenetics, the book provides a multidisciplinary overview of the main research on epigenetics. The volume includes transdisciplinary links between molecular epidemiology, nutrigenomics, biobank research, toxicology, environmental health, nutrition and medical progress in cancer and neurodgenerative diseases. It also covers methods, strategies and research developments in epigenetics. A special focus of the book is on disease prevention and treatment. This invaluable reference work is of interest to all healthcare-related professionals as well as nutritionists, and the medical community concerned with disease prevention. |
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by: George J. Febish publisher: Xlibris Corporation, published: 2011-08-30 ASIN: 1462847242 EAN: 9781462847242 sales rank: 1438854 |
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by: Cold Spring Harbor Laboratory publisher: Cold Spring Harbor Laboratory Press, published: 2005-06-01 ASIN: 0879697318 EAN: 9780879697310 sales rank: 3816380 The importance of epigenetic regulation of gene expression, particularly in higher organisms, is now clear and the 2004 Cold Spring Harbor Annual Symposium provided many new examples as well as insights into the underlying mechanisms. The resulting volume with over 60 papers from experts across the field covers various aspects of nuclear organization and dynamics; genomic imprinting, chromosomal inactivation, and other examples of gene silencing; the histone and DNA modifications associated with these conditions; and the roles of RNA and protein regulators in establishing and maintaining these states. The paperback version does not offer online access. |
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publisher: Cambridge University Press, published: 2010-04-07 ASIN: 0521895030 EAN: 9780521895033 sales rank: 1216084 This interdisciplinary book offers a unique exploration of the formative effects of children's early life experiences, with an emphasis on interactions among neurodevelopmental, behavioral, and cultural dynamics. The authors draw on insights from psychobiological, clinical, and cross-cultural comparative research that maps the robustness of these developmental dynamics across species and societies. Multidisciplinary case studies focus on specific periods of development, or windows of susceptibility, during which caregiving and other cultural practices potentially have a long-lasting impact on brain and behavior. Chapters describe in detail: how social experience interacts with neurodevelopmental disorders; how epigenetic mechanisms mediate the effects of early environment; the interaction of temperament and environmental influences; the implications of early life stress or trauma for mental health and well-being; and the cultural shaping of sexual development and gender identity. The authors also explore key aspects of and common experiences associated with modern childhood, including teasing, bullying, the function of social play, emotional regulation, and management of attention disorders. The final section translates insights from this work into a fresh appraisal of child-rearing practices, clinical interventions, and global public health policy that affect the mental health and well-being of children around the world. |
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by: Satish Totey publisher: McGraw-Hill Professional, published: 2010-01-20 ASIN: 0071635726 EAN: 9780071635721 sales rank: 2672483 Cutting-edge coverage of stem cell biology and applicationsFeaturing contributions from leading global experts, this authoritative volume addresses all major areas of stem cell biology and their potential therapeutic applications. The first part of the book covers embryonic stem cells and contains details on the emerging field of embryonic stem cell-based drug screening platforms. The second part deals with multipotent adult stem cells from different tissue types, and covers unique concepts such as cancer stem cells and tissue engineering-based approaches for designing microenvironments for tissue regeneration. Eighty pages of inserts with 113 color figures are included in this pioneering work. Coverage includes:
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