Related books on 'histopathology'
Return to life science book listNumber of products: 1207
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by: Jay H. Lefkowitch MD publisher: Churchill Livingstone, published: 1989-03-01 ASIN: 0443085668 EAN: 9780443085666 sales rank: 1579409 A text of core photomicrographs representing the spectrum of human disease. The pathology section provides overview for all organ systems and it includes an up-to-date pathology of AIDS. The emphasis is on light microscopy. |
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by: M. Trojani publisher: Lippincott Williams and Wilkins, published: 1990-11-01 ASIN: 0397583192 EAN: 9780397583195 sales rank: 9366971 |
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by: Webb Haymaker publisher: Charles C Thomas Pub Ltd, published: 1982-04 ASIN: 0398034826 EAN: 9780398034825 sales rank: 8333051 |
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by: Ching-Shen Lin publisher: Lin Pathology Publishing Company, published: 2011-05-16 ASIN: 0578078171 EAN: 9780578078175 Updated pathogenesis and mechanism of development of Preeclampsia and Eclampsia. Excerpted from Preface: Pregnancy-related convulsion (eclampsia) was recognized as early as 2,000 years ago when it was first recorded in Egyptian records and yet the pathogenesis of eclampsia (E), including preeclampsia (PE), is still not known despite two millennia of medical and scientific advancement. The proverb "To see is to believe" describes the approach of this book. Herein, I will lead you through a pathology adventure into the vascular system in PE/E to show you the real changes of PE/E through the experienced eyes of a pathologist in the 21st century. From this book, obstetricians will be able to update their knowledge of the histopathological changes of PE/E in order to understand these pregnancy-induced disease processes (pathogenesis) involved. The histopathology confirms clinical obstetrical observations, hypotheses and concepts. This book will be applicable, too, for ultrasound sonographers and radiologists to understand the changes of the uterine artery system, for women's health clinicians, cardiologists and non-physician researchers in these clinical specialties, and research pathologists who focus on current molecular biological methods or animal models to gain the pathologic basis and understanding of human hypertensive and atherosclerotic microvascular disease. This publication proposes a unifying concept that PE/E is a pregnancy-induced accelerated atherosclerotic and hypertensive microvascular disease, initiated by a maternal immune reaction and increase of placental hormones (in particular: renin, angiotensin, estrogen, and lactogen). Furthermore, PE/E is characterized by (1) atherogenic profile with hypertriglyceridemia from basal (physiological) and hypoxia-induced (pathological) lipolysis of abdominal adipose tissue, and (2) an increase of small dense low density lipoprotein (sdLDL) in maternal blood during pregnancy. From these conditions a chain of molecular biological changes occurs: endothelial activation/dysfunction, oxidative stress, inflammation, coagulopathy, and atherosis/atherosclerosis of systemic arteries and arterioles including uterine and decidual tissues that already develops prior to an onset of clinical hypertension and proteinuria defined after 20 weeks of gestation as preeclampsia. Progressive accelerated atherosclerosis first starts in the uterus which is vulnerable partly due to (a) uterine hypertension from pregnancy-induced hypervolemia, (b) trophoblast secretion of renin-angiotensin, and (c) hydrostatic pressure contributions of uterine arteries during upright posture adding approximately 20 mmHg blood pressure at uterus level, resulting in vasoconstriction and endothelial activation of uterine and decidual arterioles which leads to poor perfusion of the placenta beginning at 10 weeks gestation, and subsequently vasoconstriction of arterioles and atherosis and atherosclerosis in kidneys and other viscera. Atherosclerosis and hypertension accelerate and aggravate each other throughout the second and third trimesters resulting in clinically overt pregnancy-induced hypertensive disease, a preeclampsia syndrome, at the third trimester at an incidence of 3 to 7% of pregnancy in the USA. |
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by: E. A Marsland publisher: distributed by Yearbook Medical Publishers, published: 1975 ASIN: 0815157746 EAN: 9780815157748 sales rank: 7032300 |
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by: J. Arno publisher: Springer, published: 1980-01-31 ASIN: 0852002289 EAN: 9780852002285 sales rank: 9553775 |
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by: R.M. Marks publisher: Springer, published: 1986-10-31 ASIN: 0852003242 EAN: 9780852003244 sales rank: 10712681 |
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by: P. H. M. Schillings publisher: S Karger Pub, published: 1980-03-11 ASIN: 380550201X EAN: 9783805502016 sales rank: 5738714 |
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publisher: Kugler Pubns B V (Medical), published: 1997-01-17 ASIN: 9062991513 EAN: 9789062991518 |
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by: Paul R. Wheater publisher: Churchill Livingstone, published: 1985-10 ASIN: 0443022526 EAN: 9780443022524 sales rank: 3702367 |