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by: Philip M. Iannaccone
publisher: CRC Press, published: 1997-06-23
ASIN: 3718606127
EAN: 9783718606122
sales rank: 10724113
Animal models are critical to advancing the understanding of and intervention in human disease in almost all areas of the life sciences. This volume provides examples of how animal experimentation leads to data applicable to human disease. The ethics of animal use is explored, and details of the advantages of animal models over alternate systems are presented. The text guides the thought processes of students and scientists as they evaluate the potential use of animals in their own biomedical research.

publisher: Humana Press, published: 2010-12-01
ASIN: 1617377678
EAN: 9781617377679
sales rank: 3791596
For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy. In this essential book, leaders in the field were assembled to contribute detailed methodologies for the isolation and characterization of human and rodent MSCs. Cutting edge and easy to use, this book is the perfect resource for scientists attempting to pursue this important and ever-developing field of research.

publisher: Springer, published: 2009-08-27
ASIN: 3540881492
EAN: 9783540881490
sales rank: 4183839
Stem cell research has the potential to affect the lives of millions of people around the world. This research is now regularly front-page news, and realizing the promise of mesenchymal stem cells for yielding new medical therapies will require us to grapple with more than just scientific uncertainties. "Mesenchymal Stem Cells for the Heart - From Bench to Bedside" presents the cytobiological characteristics of mesenchymal stem cells from the isolation, culture, transmembrane ion currents, migration and differentiation in vitro to the repairing of injured myocardium and tissue reconstruction in vivo, including the results of basic research and the real possibility for treatments and ultimately for cures for cardiac diseases for which adequate therapies do not exist. The book is intended for clinical stem cell researchers in cardiovasology, hematology, cytobiology, molecular biology, cell and tissue engineering, and other related fields. Jian-an Wang, MD, PhD, Professor of Cardiology at Zhejiang University and investigator at Loma Linda University, Southern California, has broad expertise in the molecular and cellular biological processes underlying cardiovascular disease. He has won the Chinese Medical Science and Technology Medal of Honor.

publisher: Academic Press, published: 2000-08-25
ASIN: 0124014968
EAN: 9780124014961
The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines. The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.

by: Brian W.J Mahy
publisher: Academic Press, published: 2001
ASIN: 0124653278
EAN: 9780124653276
sales rank: 3758071
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