Related books on 'signal-transduction'
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publisher: Springer, published: 2001-12-01 ASIN: 0306466716 EAN: 9780306466717 sales rank: 5012859 An understanding of the mechanisms by which plants perceive environmental cues, both physical and chemical, and transduce the signals that influence specific expression of genes, is an area of intensive scientific research. With the completion of the genome sequence of Arabidopsis it is understood now that a larger number of genes encode for proteins involved in signalling cascades and transcription factors. In this volume, different chapters deal with plant receptors, second messengers like calcium ions, phosphoinositides, salicylic acid and nitrous oxide, calcium binding proteins and kinases. In addition to dealing with the response of plants to light, hormones, pathogens, heat, etc. on cellular activity, work currently going on in apoptosis, cell division, and plastid gene expression is also covered in this book. |
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publisher: Springer, published: 2006-05-24 ASIN: 0387313354 EAN: 9780387313351 sales rank: 6240592 This is the third workshop on this topic that took place in Crete from May 27 to June 1, 2005. Similar to the two previous workshops, held in Santorini October 2000 and 2002 respectively, the purpose of this workshop is to bring together scientists from all over the world to discuss their latest findings on the various aspects of lymphocyte signal transduction. The participants represented academia, industry, foundation and governmental laboratories. |
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publisher: Springer, published: 1999-05-15 ASIN: 0387986251 EAN: 9780387986258 sales rank: 5286405 Focussing on the molecular mechanisms that govern mast cell and basophil cell biology and function, this book also provides a comprehensive summary of the field of signal transduction, giving insights into areas that have therapeutic potential. It gives detailed insights into mast cell and basophil growth and development, their activation by allergens, including details of receptor activation and downstream events, and the regulators of morphology and degranulation. The metabolic pathways involved in prostaglandin and leukotriene production are discussed as is the role of transcription factors in mast cell growth and cytokine production. Written by leaders in the field, this volume will provide readers with an up-to-date account of a topic whose rapid progress makes conventional information gathering difficult. |
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by: H.J. Forman publisher: Springer, published: 1997-07-31 ASIN: 0412076810 EAN: 9780412076817 sales rank: 5756976 In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constituents. There is now evidence that reactive oxygen species (ROS) can alter cell function by acting upon the intermediates, or second messengers, in signal transductions. Such effects on signaling mechanisms probably account for the role of oxidative stress in inflammation, aging, and cancer. This volume brings together internationally recognized researchers in both the major areas covered by the book, oxidative stress and signal transduction. The work is organized in three sections. The first deals with the immediate cellular responses to oxidative stress and the production of second messengers. The second details the connection between second messengers and the gene. The third part looks more closely at the level of the gene. |
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publisher: Springer, published: 1995-02-28 ASIN: 0792333640 EAN: 9780792333647 sales rank: 11360339 Plants offer exciting opportunities to understand major biological questions, i.e. the regulation of development and morphogenesis. How are changes of the environment, developmental cues, and other signals perceived and transduced in physiological responses? What are the elements of plant signalling pathways and what is their organization? The panoply of molecular tools and techniques as well as the blossoming field of plant genetics are providing an exciting ground for major breakthroughs in unravelling the fundamental mechanisms of plant signalling. The present book establishes a state-of-the-art framework spanning the wide spectrum of perception, signal transduction events and transport processes, including cell proliferation and cell cycle regulation, embryogenesis, and flowering. Moreover, the volume emphasizes the role of the major plant signalling substances known to date (the phytohormones and more recently studied substances) and summarizes what we know on their molecular mechanisms of action. The book emphasizes how the use of molecular technology has made plant signalling processes accessible to experimental test. |
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publisher: CRC Press, published: 2006-08-15 ASIN: 084933165X EAN: 9780849331657 sales rank: 8060527 Developmental biologists have been driven to investigate growth factor signaling in embryos in order to understand the regulatory mechanisms underlying a given developmental process. Thus, it is critical to explore the technical methods and experimental designs for growth factor signaling in embryos. Focusing on specific pathways or pathway components, Analysis of Growth Factor Signaling in Embryos provides the methods and guidelines for experimental design to study major aspects of cell signaling in vertebrate embryos. The book covers a broad range of topics in signaling and a variety of current model organisms. Section I explores specific signaling pathways or pathway components. In this section, some chapters highlight the biochemistry of signaling pathways during development, which is often distinctive from that observed in cell culture systems. Section II discusses ionic regulatory mechanisms and the two chapters in Section III examine ways of investigating gene regulation in response to extracellular signals. Finally, Section IV addresses emerging strategies that facilitate integrated analyses of cell signaling in vivo in embryonic systems. Featuring contributions from expert researchers, Analysis of Growth Factor Signaling in Embryos will provide a foundation for further explorations of the cellular regulatory mechanisms governing vertebrate embryonic development. |
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by: Dallice Mills publisher: Amer Phytopathological Society, published: 1996-10-15 ASIN: 0890542155 EAN: 9780890542156 sales rank: 10800507 This volume brings together articles written by participants in the seventh seminar in the U.S.-Japan Cooperative Science Seminar series on the molecular and physiologic aspects of interactions between plants and their pathogens. The contributors examine the mechanisms that facilitate communication between the cells ofplants and pathogens and within individual cells, and the role that these mechanisms play in plant-pathogen interactions. Topics include signal transduction pathways, genic interactions, sensingof plant signals, plant disease resistance genes, and plant signal responses. |
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publisher: Humana Press, published: 1997-10-10 ASIN: 0896034739 EAN: 9780896034730 sales rank: 4917388 Prominent researchers and clinicians dissect the signaling pathways of an array of neuroprotective factors, ranging from neurotrophins (NGF, BDNF, NT-3, and NT-4/5) to growth factors (bFGF, IGF-1, GDNF), to cytokines (TNF, IL-1b, and TGFb), to secreted amyloid precursor proteins, to protease nexin-1. Also treated are cytoprotective signaling events that occur with injured neurons independently of intercellular signals. In elucidating the molecular cascades evolved by the nervous system to protect itself, the contributors lay the basis for powerful new drug discovery and gene therapy strategies, and shed light on potential effective strategies for preventing neuron degeneration in such conditions as stroke, traumatic brain injury, Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis. |
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publisher: Springer, published: 2004-04-30 ASIN: 1402078226 EAN: 9781402078224 sales rank: 8114243 Our limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of molecular cancer medicine. These signaling components are likely to be used in diagnosis, prognosis, and as novel targets for therapeutic development. This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general. |
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publisher: Amer Society for Microbiology, published: 1990-05 ASIN: 1555810217 EAN: 9781555810214 sales rank: 9506459 |