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publisher: Springer, published: 1999-01-31
ASIN: 0412838605
EAN: 9780412838606
sales rank: 7194609
This useful work presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. While there are several books written on apoptosis, this one deals specifically with its regulation.
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publisher: Wiley-Liss, published: 1995-01-15
ASIN: 0471012513
EAN: 9780471012511
sales rank: 7815936
Apoptosis and the Immune Response
Edited by Christopher D. Gregory
In this timely and important work, an international group of leading investigators takes a close and critical look at programmed cell death and its role in the development, function, and maintenance of the immune system. Along with covering the primary actions of apoptosis, the contributors probe its role in carcinogenesis and HIV-induced pathogenesis. By offering a broad range of views, Apoptosis and the Immune Response presents a current and complete picture of the various aspects and consequences of this phenomenon.
Apoptosis and the Immune Response begins with the theories surrounding apoptosis and then covers its basic mechanisms including the morphologic, biochemical, and genetic features. The book offers authoritative discussions on the role of apoptosis in the deletion of self-reactive lymphocytes, prevention of autoimmunity, termination of the immune response, death of T cells infected by the HIV virus, neoplasia, and the homeostatic regulation of the hematopoietic system.
In particular, this excellent reference critiques such topics as: * Apoptosis in thymocytes in vivo and in vitro * Bcl-2/T-cell transgenics * The role of c-myc * Fas/APO-1 antigens and their roles * Transgenic models of B-cell tolerance and autoimmunity * How apoptosis affects the pathogenesis of AIDS and the implications for therapy * Triggers for apoptosis and survival * Recognition of apoptotic cells by phagocytes * Apoptosis in peritoneal autoreactive CD5+ B cells * and more
With its diverse expertise and timely, clear-cut insights, Apoptosis and the Immune Response will prove to be an invaluable resource for immunologists, cell and developmental biologists, hematologists, and oncologists--as well as graduate students.
Cover Design: Janice Noto-Helmers
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publisher: Springer, published: 1999-10-01
ASIN: 0792386485
EAN: 9780792386483
sales rank: 8664479
Apoptosis or programmed cell death is increasingly considered to be a major factor in the development and progression of cardiovascular disease. In patients with heart failure the activation of apoptosis may result in the loss of irreplaceable cardiac myocytes promoting the clinical course of the syndrome. Moreover, in the coronary arteries inflammation and apoptosis may weaken critical structures of the vessel wall leading to plaque rupture and, subsequently, to myocardial infarction. Given these deleterious consequences, it seems almost paradoxical that programmed cell death is an active process that, if initiated under physiological circumstances, is essential for both coordinated tissue growth or destruction of malignant cells. Apoptosis in Cardiac Biology, written by a team of internationally renowned researchers, gives a timely synopsis of basic mechanisms, cellular and structural targets and, finally, clinical implications of programmed cell death in the heart. The expert authors of this volume give concise overviews on general and cell-specific aspects of programmed cell death in cardiac myocytes and fibroblasts, as well as in vascular smooth muscle and endothelial cells. Furthermore, novel therapeutic options arising from the outstanding pathophysiological significance of cardiac apoptosis are presented. This comprehensive review of Apoptosis in Cardiac Biology will be of interest to both clinicians and basic researchers who are active in the fields of cardiology and atherosclerosis.
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by: L. David Tomei
publisher: Cold Spring Harbor Laboratory Press, published: 1994-01
ASIN: 0879693959
EAN: 9780879693954
sales rank: 9044391
LXR Biotechnology, Inc., Richmond, California. Current Communications in Cell and Molecular Biology, Volume 8. Research on the genetic control of this form of programmed cell death. Companion to the 1991 volume Apoptosis: The Molecular Basis of Cell Death.
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publisher: New York Academy of Sciences, published: 2004-03
ASIN: 1573314749
EAN: 9781573314749
sales rank: 6752001
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by: Toshio Hata
publisher: University of Rochester Press, published: 1999-11-15
ASIN: 158046064X
EAN: 9781580460644
sales rank: 7670726
This work, the 13th Volume of Trophoblast Research series, comprises collected papers presented at the 4th Conference of the International Federation of Placenta Association in conjunction with the 6th Japan Placenta Association and the 16th Annual Meeting of Trophoblastic Disease (Japan), held at the Tokyo Medical Center in 1998. The papers all relate to the general theme: 'The Control Mechanisms of Proliferation and Invasive Function for Placental Trophoblastic Cells.'
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publisher: NOVA SCIENCE PUBLISHERS, published: 2006-09-06
ASIN: 1600214304
EAN: 9781600214301
sales rank: 11129593
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer.A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. The aim of this book is to provide new studies in the field of apoptosis research.
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publisher: Gazelle Distribution, published: 2006-09-06
ASIN: 1600214339
EAN: 9781600214332
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer.A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. The aim of this book is to provide untouched studies in this new and exciting field.
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publisher: Gazelle Distribution, published: 2006-10-29
ASIN: 1600214533
EAN: 9781600214530
sales rank: 10013940
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer s disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. The aim of this book is to provide new studies in the field of apoptosis research.
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publisher: Nova Science Publishers, published: 2006-10-25
ASIN: 1600215068
EAN: 9781600215063
sales rank: 7814558
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. Cancer and cell apoptosis is the central focus of this significant book.
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