Technique / Molecular Biology / DNA analysis techniques


method of choice to identify DNA bending, kinking or any other deformation?



method of choice to identify DNA bending, kinking or any other deformation?

I have a DNA binding protein(mw 6100), presumed to be a dimer and not to need any cofactors. It suppresses the replication of a certain gene by binding to its binding sequence overlaped by the promoter site of the gene. Its binding DNA sequence is much highly AT-rich.

I have some questions in studying its protein-induced DNA defomation:

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Last update 24-Feb-2002, Rating of 0 votes.

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