Technique / Molecular Biology / RNAi siRNA gene silencing / siRNA design
siRNA selector tool from wistar institute
siRNA selector tool from wistar institute
Computing tool provided by Wistar Institute, University of Pennsylvania.
A set of rules was used for evaluating siRNA functionality based on thermodynamics parameters (Khvorova A et al., 2003, Schwarz et al 2003) and sequence-related determinants developed by Dharmacon . (Reynolds et al 2004) . Specificity is determined using BLAST against UniGene databases.
Last update 29-Apr-2007, Rating of 0 votes.
