siRNA selector tool from wistar institute

Computing tool provided by Wistar Institute, University of Pennsylvania.

A set of rules was used for evaluating siRNA functionality based on thermodynamics parameters (Khvorova A et al., 2003, Schwarz et al 2003) and sequence-related determinants developed by Dharmacon . (Reynolds et al 2004) . Specificity is determined using BLAST against UniGene databases.

Last update 29-Apr-2007, Rating n/a of 0 votes.