Technique / Genetics / Genetic Screening / Heteroduplex analysis
Heteroduplex and SSCP Analysis
Heteroduplex and SSCP Analysis
In heteroduplex analysis, the conformational properties of the double stranded molecules are used to distinguish different base pairing (i.e. mutations), based on the differing mobilities.
Single Stranded Conformational Polymorphism (SSCP) refers to the differing migration properties of single stranded molecules affected by variations in base sequence (from Serva electrophoresis).
Last update 19-Dec-2006, Rating of 1 votes.
