Technique / Proteomics and protein biochemistry / Protein expression, protein extraction and protein purification / Baculovirus expression system
PERSPECTIVES ON BACULOVIRUS EXPRESSION SYSTEMS
PERSPECTIVES ON BACULOVIRUS EXPRESSION SYSTEMS
A mini review by Dr. Bart Frank, Arthritis and Immunology Program, Oklahoma state University.
In a previous session, advantages of expressing heterologous genes in E. coli were discussed. While high levels of expression in bacterial systems are common, problems of proper folding and lack of post-translational processing may produce functionally inactive molecules. The baculovirus expression system can be used to circumvent these problems.
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